Grounded in scholarship regarding post-object fandom, parasocial break-ups and parasocial grief, this research explored tweets regarding the death of a long-running, central character on the TV show Grey’s Anatomy. A theory-driven thematic analysis revealed five major themes including: emotional expressions of grief, recovery and coping, advocating, not wanting to watch, and memorializing, each encompassing various subthemes. Fans expressed these responses with varying levels of intensity. The results suggest that there are fan responses to a parasocial break-up, especially a parasocial death, not suggested in prior studies that should be examined in future research. Furthermore, a parasocial break-up can be a powerful experience for fans even disrupting their everyday lives.