Information science is an interdisciplinary field that deals with the effective collection, storage, retrieval, and use of information for better decision making through related technologies. Today, healthcare organizations are looking for more efficient and sophisticated means of collecting, managing, analyzing data, and delivering medical information to physicians, clinicians, and nurses. The role of information science in the healthcare domain is to improve the quality of patient care, reduce operational cost, and make the entire internal management process well organized for better decision making. Through the application of technology, data analytics and information science practitioners help drive data-informed healthcare decisions. Hence, this chapter covers the techniques that are useful for data analytics and information management in healthcare such as data mining, machine learning, cloud computing, and data visualization.