The issues of obtaining silica optical fibers with SiO2/SiO2-F composition (where SiO2 is a core, and SiO2-F is a light-reflecting cladding) with low optical losses for the near-IR spectral range are considered. This fiber type is widely used in various fields of science and technology, including laser medicine. The study results of the dependence of the numerical aperture and fluorine concentration in silica glass of the formed fiber preforms on the Freon (C3F8) consumption in the gas phase when using a waveguide-type microwave plasmotron at the H10 wavelength, are presented. It is showed that to increase the fluorimeters sensitivity in the near-IR spectral range as probe fibers for detecting luminescence, it is promising to use quartz-quartz fibers with the “Heraeus” glass core and the reflective SiO2-F cladding with an increased fluorine content in the glass (up to 7 wt. %). In this case, the numerical aperture of such fibers will reach values up to 0.32. For laser procedures in ophthalmology, surgery, phlebology and etc., optical fibers with a standard numerical aperture 0.20-0.24 can be used (with a fluorine concentration in the glass up to 3 wt. %).