Correction: Redox-active ligand based Mn(i)-catalyst for hydrosilylative ester reduction

Correction for ‘Redox-active ligand based Mn(i)-catalyst for hydrosilylative ester reduction’ by Soumi Chakraborty et al., Chem. Commun., 2021, 57, 12671–12674, DOI: 10.1039/D1CC05614J.

Tuneable photoluminescence of TBAPY-based Metal-Organic Complex

We report the synthesis of crystals of an organic metal complex based on a large redox-active ligand (tbapy) exhibiting luminescent properties. We have demonstrated the tuning of the luminescence of a Zn-based metal-organic complex, soaked in advance in dimethylformamide, with pumping light.

Advances in Magnetic Nanoparticle-Driven Delivery of Gene Therapies towards Prostate Cancer

Conventional treatment possibilities for one of the most common diseases among men, i.e., prostate cancer has several side effects. Gene-based therapy such as siRNA, CRISPR/Cas9, pDNA, and miRNA have emerged as an alternative, combating posttherapy side effects and drug resistance. Magnetic nanoparticles have been appropriately modified and functionalized to efficiently deliver the gene therapy-based active compounds to prostate tumor cells. The main purpose of this review article is to highlight the strategies currently being utilized for the treatment of prostate cancer using magnetic nanoparticles for delivery of genetic material using both the passive and active (ligand-based) targeting. It further discusses the challenges in efficient delivery of therapeutics to tumor sites and their remedial approaches. Finally, it provides a glimpse of future advances for tumor-specific modifications of magnetic nanoparticles to combat prostate cancer.

First d0 Metal-Catalyzed Alkyl–Alkyl Cross Coupling Enabled by a Redox-Active Ligand

Alkyl–alkyl cross coupling through well-defined mechanisms that allow for controlled oxidative addition, prevent beta-hydride elimination, and tolerate hindered electrophiles are still challenging. We describe the first report of a redox-active ligand-enabled alkyl–alkyl cross coupling using a d0 metal. This (tris)amido ScIII complex as well as the oxidized variant are thor-oughly characterized (NMR, X-ray, EPR, CV, UV-Vis, DFT). Insight into the likely radical nature of the mechanism is dis-closed. Additionally, a substrate scope that includes functional groups incompatible with late transition metal catalysis, and both coupling partners bearing beta-hydrogens is reported.