In this study, fuzzy logic modeling was implemented to fuse the thematic layers derived from principal components analysis (PCA) in order to generate mineral prospectivity maps. Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and WorldView-3 (WV-3) satellite remote sensing data were used. A spatial subset zone of the Central Iranian Terrane (CIT), Iran was selected in this study. The PCA technique was implemented for the processing of the datasets and for the production of alteration thematic layers. PCA4, PCA5, and PCA8 were selected as the most rational alteration thematic layers of ASTER for the generation of a prospectivity map. The fuzzy gamma operator was used to fuse the selected alteration thematic layers. The PCA3, PCA4, and PCA6 thematic layers (most rational alteration thematic layers) of WV-3 were fused using the fuzzy AND operator. Field reconnaissance, X-ray diffraction (XRD) analysis, and Analytical Spectral Devices (ASD) spectroscopy were carried out to verify the image processing results. Subsequently, mineral prospectivity maps were produced showing high-potential zones of Pb-Zn mineralization in the study area.