PROFIL PASIEN KO-INFEKSI TUBERCULOSE-HIV DI RSUD DOK II JAYAPURA Tuberculosis-HIV Co-infection Profile in DOK II Hospital Jayapura

AbstrakPapua adalah daerah yang memiliki angka prevalensi HIV-AIDS tertinggi di Indonesia. Infeksi TB adalah infeksi oportunistik terbanyak yang menyerang pasien HIV-AIDS. Tujuan penelitian ini adalah untuk mengetahui profil pasien koinfeksi TB-HIV yang mendapatkan pengobatan obat anti tuberculosis (OAT) di klinik VCT RSUD Dok II Jayapura selama periode Januari 2011 hingga September 2012. Penelitian ini merupakan penelitian retrospektif deskriptif. Data diambil dari rekam medik, kartu TB 01 dan hasil mikrobiologis pasien koinfeksi TB-HIV yang mengambil OAT di klinik VCT RSUD Dok II Jayapura. Hasil penelitian menunjukkan bahwa 35 dari 124 pasien adalah pasien default yang mengalami efek samping obat dan tidak memiliki Pengawas Minum Obat (PMO). Efek samping obat TB menjadi kendala selama pengobatan sehingga peranan PMO yang berasal dari keluarga inti mampu membantu pasien menyelesaikan pengobatan TB tersebut. Kata kunci: AIDS, pengawas minum obat (PMO), rifampisin, tuberculosis, AbstractPapua shows the highest prevalency rate of HIV-AIDS in Indonesia and almost 60% people who live with HIV develop tuberculosis (TB), hence TB is the most common opportunistic infection in HIV patients. This study was aimed to know and to describe the profile of TB-HIV co-infection patients among TB patients according to clinical symptoms and the side effects of FDC (Fixed Dose Combination) drugs. Methods used was descriptive study taken from medical record of 124 TB-HIV co-infection patients in Dok II Jayapura hospital, Papua during January 2011 – September 2012. Results showed that 35 of 124 patients indicated side effect of antituberculosis risk default when they did not undergo drug monitoring therapy. The patients should be controlled by his/her family to help them through all the side effects of antituberculose drugs to complete the treatment. Keywords: AIDS, drug monitoring therapy, rifampicin, tuberculosis

Respons Orang Hidup Dengan HIV AIDS (OHIDHA) Dalam Upaya Penanggulangan HIV AIDS di Kabupaten Sukoharjo dan Grobogan

ABSTRAKPenanggulangan HIV AIDS membutuhkan keterlibatan dari berbagai pihak. Salah satu pihak yang terlibat adalah OHIDHA. OHIDHA merupakan anggota keluarga yang hidup bersama ODHA dan memberikan dukungan kepada ODHA. Stigma di Kabupaten Sukoharjo dan Grobogan masih tinggi. Penelitian ini bertujuan untuk mengetahui faktor-faktor apakah yang menentukan respons OHIDHA dalam upaya penanggulangan HIV AIDS di Kabupaten Sukoharjo dan Grobogan.Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional. Teknik pengambilan data kuantitatif melalui wawancara dengan kuesioner. Penelitian ini didukung dengan penelitian kualitatif dengan teknik pengambilan data FGD. Jumlah responden adalah 92 OHIDHA, proporsi 50% dan selang kepercayaan 95%. Analisis data menggunakan analisis univariat dengan distribusi frekuensi, bivariat menggunakan Chi-Square dan multivariat menggunakan regresi logistik.Hasil penelitian menunjukkan bahwa variabel yang berhubungan dengan respons OHIDHA adalah hubungan dengan ODHA (p-value=0,001), lama hidup dengan ODHA (p-value=0,030), lama mengetahui status ODHA (p-value=0,001) dan sikap (p-value=0,005). Hasil analisis multivariat menunjukkan bahwa sikap (p-value=0,006) merupakan variabel yang mempunyai pengaruh paling signifikan dibanding variabel lainnya.Kata Kunci : OHIDHA, respons, Grobogan, Sukoharjo Respons of People Living With HIV AIDS to Control HIV and AIDS in Sukoharjo and Grobogan District; Controlling HIV and AIDS requird the involvement of various sector. One of the sector involved is People Living With HIV AIDS (PLWHA). PLWHA is a family member who lives with people living with HIV and provide support to people living with HIV. Stigma in Sukoharjo and Grobogan still high. This study aims to determine the factors that determine whether the PLWHA response in control to HIV and AIDS in Sukoharjo Grobogan. This research was a quantitative study with cross sectional approach. Quantitative data collection techniques through interviews with questionnaires . This research was supported by qualitative research with FGD. The number of respondents was 92 PLWHA, the proportion of 50% and 95% confidence interval . Analysis of the data using univariate analysis with frequency distribution, bivariate using Chi-Square and multivariate using logistic regression. The results showed that the variables related to the PLWHA response is a relationship with people living with HIV ( p = 0,001 ) , long life with people living with HIV ( p = 0.030 ) , longer know the status of PLWHA ( 0.001 ) and attitude ( p = 0.005 ). Multivariate analysis showed that the attitude (p value = 0,006) was a variable that has the most significant effect compared to other variables .Keywords : AIDS , response , Grobogan , Sukoharjo

Aids in Africa

AIDS (Acquired Immunization Deficiency Syndrome), first described in I 9 8 I in the United States, is at present ascertained on every continent. Since its description, our knowledge about AIDS has advanced with giant steps, with regard to its causal agent, clinical image, biological effects and epidemiology. Although it is everywhere the same disease, its epidemiology and impact on society vary from one continent to another depending on the human, social and economic conditions of the countries which are affected. The first African cases were noticed in 1983. Since then the presence of AIDS has been confirmed in numerous sub-Saharan African countries. Our goal is to present here some characteristic features of the AIDS-epidemic in Africa and to offer some points of reflection for future action. KEYWORDS : AIDS, Africa, diagnostics, epidemiology, treatment