Basal cell papilloma of the external auditory canal: a case report

<p class="abstract">Basal cell papilloma are benign neoplastic lesion affecting skin, oral mucosa, trunk and genital organs. However it is uncommon to originate in the external auditory canal.We present a 32-year old female presented with otalgia, reduced hearing and bleeding intermittently from the left ear. Clinically it showed multilobulated, blackish mass obliterating the external auditory canal. The mass was friable and bleed to touch. Excision biopsy was done under general anaesthesia and she had uneventful recovery. The histopathology reported as seborrhoeic keratosis or Bbasal cell papilloma. No dysplasia or malignancy seen. In conclusion, basal cell papilloma of the external auditory canal is rare and complete excision of the lesion ensures good outcome and recovery.</p>

Lesions of pinna in a tertiary care hospital in Dakshina Kannada

Introduction and Aim: Most of the lesions affecting pinna are cutaneous conditions. Those arising from the cartilage are extremely rare, whereas those from the soft tissue like vascular, stromal and adnexal components are relatively common. The present study aims at analysing the proportion, types, and categories of lesions affecting the pinna. Methods: Following institutional ethics committee approval, a retrospective analysis of medical records of 40 patients who underwent surgical excision of pinna lesions from 2006 to 2018 was conducted at a tertiary care hospital in Dakshina Kannada, India. Lesions were grouped as benign adnexal, benign soft tissue, malignant lesions, and infection/inflammation. Results: Median age was 47.5 years and mode was 59 years. There were thirty (75%) males and ten (25%) females. The commonest lesions included epidermal cyst (25%), followed by seborrhoeic keratosis (17.5%), and squamous cell carcinoma (10%). Conclusion: A wide spectrum of entities affecting the pinna were encountered in the present study. Superficial cystic lesions are the most frequent type found in pinna and are amenable to simple excision. Benign neoplasms require surgical intervention; malignancy is also to be kept in mind while making a clinical diagnosis, necessitating wide clearance with or without neck dissection. Early intervention and confirmation of diagnosis by histopathological examination helps not only in successful management but also in preventing disfigurement and psychosocial complications.

Panitumumab-Induced Eruptive Seborrhoeic Keratosis in a Patient with Metastatic Colorectal Cancer

Objectives: Agents targeting the epidermal growth factor receptor (EGFR)-mediated signalling pathway are increasingly being used for the treatment of advanced lung, pancreatic, colorectal and head and neck cancers. Case presentation: Here, we report the first case of eruptive seborrhoeic keratosis following panitumumab treatment, an anti-EGFR monoclonal antibody, in a 73-year-old patient with stage 4 (IV) colorectal cancer with hepatic metastasis. Conclusion: While panitumumab is an emerging therapy for RAS wild-type metastatic colorectal cancer, physicians should consider panitumumab as a potential cause of eruptive seborrhoeic keratosis.