The purpose of the study is to improve the adaptation system for personnel in a multidisciplinary hospital. Results: the problems of organizing the adaptation process were identified, the methods of analysis and assessment of the management of the adaptation process in a medical organization were adapted, the effectiveness of the existing system of adaptation of medical workers in the organization was assessed. Conclusion: the study proved the need for a more complete and high-quality adaptation process; the process is not static, a creative approach is needed, taking into account the characteristics of the organization (team) and the individual abilities of a specialist; to improve the organization, for the effective adaptation of medical personnel, it is necessary to develop the institution of mentoring.