Prior studies have shown an ambiguous relationship between gas hydrate saturation and seismic attenuation in different regions, but the effect of gas hydrate morphology on seismic attenuation of hydrate-bearing sediments was often overlooked. Here we combine seismic data with rock physics modeling to elucidate how gas hydrate saturation and morphology may control seismic attenuation. To extract P-wave attenuation, we process both the vertical seismic profile (VSP) data within a frequency range of 30 – 150 Hz and sonic logging data within 10 – 15 kHz from three wells in the south Hydrate Ridge, offshore of Oregon (USA), collected during Ocean Drilling Program (ODP) Leg 204 in 2000. We calculate P-wave attenuation using spectral matching and centroid frequency shift methods, and use Archie's relationship to derive gas hydrate saturation from the resistivity data above the bottom simulating reflection (BSR) at the same wells. To interpret observed seismic attenuation in terms of the effects of both gas hydrate saturation and morphology, we employ the Hydrate-Bearing Effective Sediment (HBES) rock physics model. By comparing the observed and model-predicted attenuation values, we infer that: (1) seismic attenuation appears to not be dominated by any single factor, instead, its variation is likely governed by both gas hydrate saturation and morphology; (2) the relationship between seismic attenuation and gas hydrate saturation varies with different hydrate morphologies; (3) the squirt flow, occurring at different compliances of adjacent pores driven by pressure gradients, may be responsible for the significantly large or small attenuation over a broad frequency range.