Experimental Demonstration of a Stacked Hybrid Optoacoustic-Piezoelectric Transducer for Localized Heating and Enhanced Cavitation

Laser-generated focused ultrasound (LGFU) is an emerging modality for cavitation-based therapy. However, focal pressure amplitudes by LGFU alone to achieve pulsed cavitation are often lacking as a treatment depth increases. This requires a higher pressure from a transmitter surface and more laser energies that even approach to a damage threshold of transmitter. To mitigate the requirement for LGFU-induced cavitation, we propose LGFU configurations with a locally heated focal zone using an additional high-intensity focused ultrasound (HIFU) transmitter. After confirming heat-induced cavitation enhancement using two separate transmitters, we then developed a stacked hybrid optoacoustic-piezoelectric transmitter, which is a unique configuration made by coating an optoacoustic layer directly onto a piezoelectric substrate. This shared curvature design has great practical advantage without requiring the complex alignment of two focal zones. Moreover, this enabled the amplification of cavitation bubble density by 18.5-fold compared to the LGFU operation alone. Finally, the feasibility of tissue fragmentation was confirmed through a tissue-mimicking gel, using the combination of LGFU and HIFU (not via a stacked structure). We expect that the stacked transmitter can be effectively used for stronger and faster tissue fragmentation than the LGFU transmitter alone.

Analysis of Ultrasonic Pulse Generated by Piezoelectric Material (LiNbO3 Cut Y-X) Using SVM Classifier

In this paper, we propose a new numerical method for ultrasonic pulse detection of an acoustics microwaves signal during the propagation of acoustics microwaves generated by piezoelectric substrate LiNbO3 Cut Y-X in ultrasonic transducer. We have used the classifications by support vector machines (SVM) , the originality of this method is it provides the accurate values and help us to identify undetectable waves that we can not identify with the classical methods; in which we classify all the values of the real part and the imaginary part of the coefficient attenuation with the acoustic velocity in order to build a model from which we note the Ultrasonic Pulse or microwaves acoustics ( bulk waves ). By which we obtain accurate values for each of the coefficient attenuation and acoustic velocity. This study will be very interesting in modeling and realization of acoustics microwaves devices (ultrasound) based on the propagation of acoustics microwaves.

Strong electric field tuning of magnetism in self-biased multiferroic structures

A new type of multiferroic heterostructure has been proposed in this work with strong electric field tuning of magnetism. It is composed of a self-biased magnetic layered structure with perpendicular magnetic anisotropy (PMA) and one piezoelectric substrate. Two configurations were investigated by a modeling approach, Ni/Ni/Ni/PMN-PT with Cu as spacer and Terfenol-D/CoFeB/Ni/PMN-PT. Magnetic multilayers at their resonance exhibit multiple absorption peaks from acoustic and optical modes of spin interaction between adjacent magnetic layers. A piezoelectric substrate transfers electric field induced strain to adjacent magnetic layer and thus shifts resonance frequencies of the multiferroic structure by tuning magnetic effective fields through magnetoelastic coupling. It has been demonstrated computationally that the resonance frequencies for the simulated structures could be up to 76 GHz under zero magnetic bias field. A larger tunability (> 100%) is achieved with applied electric field to the PMN-PT [011] substrate. Resonance mode selectivity is present in the configuration Terfenol-D/CoFeB/Ni/PMN-PT wherein one desired mode exhibits a much higher tunability compared to other modes. This enables the total mode number to be tuned by merging or diverging different modes under E-field.