Jean Piaget’s Genetic Epistemology as a Theory of Knowledge Based on Epigenesis

This article aims to highlight Jean Piaget’s theory of knowledge and situate it in this context since its beginnings in Ancient Greece where, in Plato, we already find this seminal idea: knowledge is acquired in successive and upward moments (dialektikê), starting from an opinion on the sensible world (doxa) towards the épistêmê of the intelligible world, the world of Ideas or concepts. Piaget’s Theory of Knowledge, we believe, was determined by four moments: 1) his research as a malacologist under the guidance of Godet and Raymond, 2) the acquaintance with Kant’s philosophy at age of 21, 3) his internship at the Binet/Simon laboratory, 4) his studies on the Limnaea Stagnalis. His core idea: it is possible for human beings to attain the necessary and universal knowledge due to the exchange processes of their organisms with the environment, which give rise to the epigenetic ontogenesis of their specific organic mental structures, framed for the specific act of knowing. Epigenetic ontogenesis begins with the infans first actions in the world, from the very moment of birth. Around two years of age, these actions will be represented and organized in groups linked to empirical experience, until the brain be able to perform the operations of the Abelian Group. The physiological development ends here, and the logico-mathematical knowledge becomes possible.

Interrelationships between Golgi, GERL and synaptic vesicles in the nerve cells of insect and gastropod ganglia

In addition to demonstrating synaptic vesicles, staining with the zinc-iodide-osmium tetroxide (ZIO) method reveals the presence of positively reacting GERL membranes in association with the Golgi complex and lysosomes in the nerve cell bodies within ganglia from the locust Schistocerca gregaria and the gastropod molluscs, Limnaea stagnalis and Helix aspersa. A positive response to ZIO occurs in certain Golgi vesicles and saccules, in GERL (Golgi-endoplasmic-reticulum-lysosomes), in multivesicular bodies as well as residual bodies and in small vesicles and cisternae of axonal smooth endoplasmic reticllum (ER). The interrelationships between these organelles are considered in view of the similarity of the ZIO localization to phosphatase-rich sites in the neuronal perikarya and with respect to the possibility that components of the synaptic vesicles are formed in the Golgi region of the cell and migrate via the axonal smooth ER to the synaptic regions.