Abstract
BackgroundTranslational medicine(TM)is a bridge between basic science and clinical medicine. The purpose of this study is to systematically review the literature with respect to fracture mapping(FM) in orthopedics, to clarify what insights and challenges facing FM. MethodsA systematic review was conducted according to PRISMA guidelines. We systematically searched the PubMed, Scopus, IEEE Digital Library, Web of Science database and references of relevant studies, from the establishment of the database through December 2020, for any and all data regarding the application of FM in orthopedics. ResultsA total of 2777 articles were retrieved, and 28 articles met the inclusion criteria. The application of fracture FM in orthopaedics was as follows: upper limbs (n=10, 35.71%), lower limbs (n=17, 60.71%), thoracolumbar spine (n=1, 3.58%). FM guided preoperative planning (n = 12, 42.86%), and conduce to identify the specific patterns of fractures (n=9, 32.14%), and illustrated the fracture morphology and guided clinical treatment (n=7, 25.00%). ConclusionFM represents a promising technique for describing the morphology of fracture. Moreover, potential promotion classification, preoperative planning, development of fixation concepts, and analysis of internal structure, but its clinical application is still limited. Thus, much further research is needed to determine the potential advantages of this new technique. If possible, guidelines are needed to facilitate the development of FM with regard to the required for developing this technic.