Randomized approach to determine dynamic strength of ice

The randomized method of Sign-Perturbed Sums (SPS) is applied within the framework of the incubation time approach to evaluate the dynamic strength of ice. The experimental data of [Carney et al., 2006; Wu and Prakash, 2015; Saletti et al., 2019] is analysed in order to estimate strength parameters of ice and describe the observed strain-rate sensitivity curves. The independence of incubation time value on the ice temperature is established in contrast with the significant dependency of the critical stress parameter. The obtained confidence interval of the spalled ice is in good correspondence with the scatter observed experimentally.

Golub–Kahan vs. Monte Carlo: a comparison of bidiagonlization and a randomized SVD method for the solution of linear discrete ill-posed problems

Randomized methods can be competitive for the solution of problems with a large matrix of low rank. They also have been applied successfully to the solution of large-scale linear discrete ill-posed problems by Tikhonov regularization (Xiang and Zou in Inverse Probl 29:085008, 2013). This entails the computation of an approximation of a partial singular value decomposition of a large matrix A that is of numerical low rank. The present paper compares a randomized method to a Krylov subspace method based on Golub–Kahan bidiagonalization with respect to accuracy and computing time and discusses characteristics of linear discrete ill-posed problems that make them well suited for solution by a randomized method.

Correction of psychoemotional and vascular-autonomic dysfunction with patients suffering from endometrial disease under the influence of complex radon, laser, and drug treatment

The research objective is to develop a program to correct psycho-emotional and vascular-autonomic dysfunction with patients suffering from adenomyosis using complex radon, laser and drug treatment. Material and methods. There were 100 women with adenomyosis complicated by psycho-emotional and vascular-autonomic dysfunction from the age of 23 up to 37 years old who underwent treatment at a branch of Pyatigorsk Clinic of North Caucasian Federal Scientific and Clinical Centre of Federal Medical and Biological Agency of Russia. The patients were divided into 2 groups by a randomized method: the main group received radon, laser and drug therapy with Melaxen, the group of comparison received radon and laser therapy. Results. A comparative analysis showed the expediency of including adaptogens in the complex of sanatorium-and-spa treatment of patients with endometrial disease: the improvement of clinical symptoms in the main group compared to the group of comparison was more frequent by 1.36 times; normalization of vegetative management in the main group occurred with 72% of the patients compared to 52% in the group of comparison; in the main group the decrease in the intensity of anxious disorders was 2.64 times (p 0.01), against 1.46 times in the group of comparison (p 0.05); normalization of concentration of peptide and steroid hormones in blood serum in the main group was with 64% of the patients versus 42% in the group of comparison. Conclusion. Inclusion of Melaxen in the complex of traditional sanatorium-and-spa treatment of patients with adenomyosis (radon and laser therapy) provides significant improvement of neuroendocrine system, psycho-emotional, vegetative-vascular status.

Transpancreatic biliary sphincterotomy versus double guidewire in difficult biliary cannulation: a randomized controlled trial

Background Difficult biliary cannulation in endoscopic retrograde cholangiopancreatography (ERCP) increases the risk of post-ERCP pancreatitis (PEP). The purpose of this prospective, randomized, multicenter study was to compare two advanced rescue methods, transpancreatic biliary sphincterotomy (TPBS) and a double-guidewire (DGW) technique, in difficult common bile duct (CBD) cannulation. Methods Patients with native papilla and planned CBD cannulation were recruited at eight Scandinavian hospitals. An experienced endoscopist attempted CBD cannulation with wire-guided cannulation. If the procedure fulfilled the definition of difficult cannulation and a guidewire entered the pancreatic duct, randomization to either TPBS or to DGW was performed. If the randomized method failed, any method available was performed. The primary end point was the frequency of PEP and the secondary end points included successful cannulation with the randomized method. Results In total, 1190 patients were recruited and 203 (17.1 %) were randomized according to the study protocol (TPBS 104 and DGW 99). PEP developed in 14/104 patients (13.5 %) in the TPBS group and 16/99 patients (16.2 %) in the DGW group (P = 0.69). No difference existed in PEP severity between the groups. The rate of successful deep biliary cannulation was significantly higher with TPBS (84.6 % [88/104]) than with DGW (69.7 % [69/99]; P = 0.01). Conclusions In difficult biliary cannulation, there was no difference in PEP rate between TPBS and DGW techniques. TPBS is a good alternative in cases of difficult cannulation when the guidewire is in the pancreatic duct.

Application of Empty Fruit Bunches Compost and Types of P Fertilizer on the Growth and Phosphorus Uptake in Oil Palm Seedlings

<p>This research aimed to evaluate the effect of empty fruit bunches (efb) compost, phosphate-solubilizing bacteria (PSB), lime, and types of P fertilizer on the growth and availability of Phosphorus and P uptake in the pre-nursery (PN) oil palm seedlings in latosols. The pot experiments were arranged in a Factorial Completely Randomized method. The first factor was the application of efb compost: without efb compost, efb compost, without efb compost + PSB, and without efb compost + lime. The second factor was the types of P fertilizer: SP-36, RP, guano, and NPKMg + Urea as a control. The results showed that the combination of without efb compost +lime and RP fertilizer produces the highest number of leaves. The influence of a single factor showed that the application of without efb, efb compost, without efb compost +PSB, without efb compost + lime, resulted in the same growth of seedlings, except on plant height and the length of the leaf. The various types of P fertilizer led to the same growth of seedlings except for stem diameter. The highest available P was obtained in the combination of without efb compost + PSB with SP-36 fertilizer, which was 631.1% compared to control (without efb compost and NPKMg, Urea) and the lowest in the combination of without efb compost + lime with (NPKMg, Urea). The treatment without efb compost + lime with SP-36 fertilizer increased P uptake of leaves by 55.6% and stem by 47.1% compared to control.</p>

RESPON PERTUMBUHAN DAN HASIL JAMUR TIRAM PADA KONSENTRASI NPK DAN FREKUENSI PENYIRAMAN

This research to determine the concentration and frequency of watering on growth and yield of Oyster Mushrooms. The Research used a Randomized Method with two factors, The first factor was NPK concentration which consisted of 3 level : A1 = 0 %, A2 = 10%, A3 = 30 % and the second factor was the frequency of watering consisting of 3 level, B1 : 1 time, B2 : 2 time, B3 : 3time. The result showed that the NPK concentration treatment had a significant KONSENTRASI affected on mushroom 12 week after plant, significantly affected of mushroom/baglog and weight of mushroom/baglog 12 week after plant, but no significant effect weight on mushroom 8 week after plant. The frequency of watering had significant effect of amound mushroom/baglog and weigth mushroom 12 week after plant, significantly effect on the weigt mushroom/baglog 8 week after plant and had no significant effection other parameter. The interaction between the NPK concentration and frequency of watering only had significant effected the weight of mushroom 8 week after plant. Concentration NPK10 % (A2) and 2 times watering frequency (B2) showed the best oyster mushroom result.

Fast estimation of genetic correlation for Biobank-scale data

Genetic correlation is an important parameter in efforts to understand the relationships among complex traits. Current methods that analyze individual genotype data for estimating genetic correlation are challenging to scale to large datasets. Methods that analyze summary data, while being computationally efficient, tend to yield estimates of genetic correlation with reduced precision. We propose, SCORE, a randomized method of moments estimator of genetic correlation that is both scalable and accurate. SCORE obtains more precise estimates of genetic correlations relative to summary-statistic methods that can be applied at scale achieving a 50% reduction in standard error relative to LD-score regression (LDSC) and a 26% reduction relative to high-definition likelihood (HDL) (averaged over all simulations). The efficiency of SCORE enables computation of genetic correlations on the UK biobank dataset consisting of ≈ 300K individuals and ≈ 500K SNPs in a few hours (orders of magnitude faster than methods that analyze individual data such as GCTA). Across 780 pairs of traits in 291, 273 unrelated white British individuals in the UK Biobank, SCORE identifies significant genetic correlation between 200 additional pairs of traits over LDSC (beyond the 245 pairs identified by both).