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2021 ◽  
Vol 2 (1) ◽  
pp. 43-50
Author(s):  
Dara Prameswari ◽  
Nita Parisa ◽  
Muhammad Totong Kamaluddin

Rationality of Diclofenac Use in Osteoarthritis Outpatient Case at RSUP MHPalembang in January-March 2018. Osteoarthritis (OA) is the most common diseasein joints that affects people in their middle until late years. In Indonesia the prevalenceof OA is relatively high and disturbs their daily activity. Diclofenac is one of the drug ofchoice in treating OA. To avoid multiple side effects from Diclofenac use, the usagemust be in accordance to rationality indicators which are correct dose, correctfrequency, and correct length of use. This study is aimed to know the rationality ofDiclofenac use in Osteoarthritis outpatient cases at RSUP Mohammad HoesinPalembang. This study is a descriptive observational with a cross-sectional approachto know the rationality of Diclofenac use in outpatient cases of osteoarthritis at RSUPMohammad Hoesin Palembang. Samples were medical records of OA patients inoutpatient setting from January to March 2018 which fulfilled the inclusion andexclusion criteria. Sampling technique used was total sampling. The amount ofsamples fulfilling the inclusion criteria were 201 patients, with the most were aged 46-65 years (60.2%), female (55.7%), and has a history of comorbidity which includes lowback pain (22.8%). The result of this study shows pattern of Diclofenac use with dosageof 2 x 25mg (73.6%), length of use about <7 days (57.2%). In combination with otherdrugs there were no interaction to be found (84.4%), or synergistic interaction (8.5%)and antagonistic interaction (7.1%). The use of diclofenac in osteoarthritis cases atoutpatient setting in RSUP Dr Mohammad Hoesin Palembang is rational and needs tobe maintained.


2021 ◽  
Vol 2 (1) ◽  
pp. 43-50
Author(s):  
Dara Prameswari ◽  
Nita Parisa ◽  
Muhammad Totong Kamaluddin

Rationality of Diclofenac Use in Osteoarthritis Outpatient Case at RSUP MHPalembang in January-March 2018. Osteoarthritis (OA) is the most common diseasein joints that affects people in their middle until late years. In Indonesia the prevalenceof OA is relatively high and disturbs their daily activity. Diclofenac is one of the drug ofchoice in treating OA. To avoid multiple side effects from Diclofenac use, the usagemust be in accordance to rationality indicators which are correct dose, correctfrequency, and correct length of use. This study is aimed to know the rationality ofDiclofenac use in Osteoarthritis outpatient cases at RSUP Mohammad HoesinPalembang. This study is a descriptive observational with a cross-sectional approachto know the rationality of Diclofenac use in outpatient cases of osteoarthritis at RSUPMohammad Hoesin Palembang. Samples were medical records of OA patients inoutpatient setting from January to March 2018 which fulfilled the inclusion andexclusion criteria. Sampling technique used was total sampling. The amount ofsamples fulfilling the inclusion criteria were 201 patients, with the most were aged 46-65 years (60.2%), female (55.7%), and has a history of comorbidity which includes lowback pain (22.8%). The result of this study shows pattern of Diclofenac use with dosageof 2 x 25mg (73.6%), length of use about <7 days (57.2%). In combination with otherdrugs there were no interaction to be found (84.4%), or synergistic interaction (8.5%)and antagonistic interaction (7.1%). The use of diclofenac in osteoarthritis cases atoutpatient setting in RSUP Dr Mohammad Hoesin Palembang is rational and needs tobe maintained.


2019 ◽  
pp. 96-100
Author(s):  
E. P. Sharapova ◽  
L. I. Alekseeva

Knee and hip joint pain is the first and most common symptom that forces a patient to visit the doctor. Osteoarthritis (OA) treatment is aimed «primarily» at managing symptoms of the disease, i.e. reducing pain, improving the functional state of the joints, and finally at improving the patients’ quality of life. The Russian and international organizations have developed numerous guidelines for the treatment of OA, which include non-pharmacological and pharmacological methods, among which symptomatic slow-acting drugs are of special interest. These drugs are currently recommended to prescribe as the first-line drugs to treat OA. Analgesics and NSAIDs that rarely cause adverse effects, especially in older people and in patients with co-morbidities, who receive concomitant medications, are the most commonly prescribed medications for pain relief. This creates a problem when the drugs affect one another’s exposure and can limit the prescription of a range of drugs, which determines an increase in interest in other drugs called sustained-release symptomatic drugs, which are widely recognized in arthrology.The article presents the results of studies of Artra and Artra MSM Forte in patients with hip and knee OA, which were conducted in Russia.


2019 ◽  
Vol 7 (1) ◽  
pp. 55-66
Author(s):  
Tyas Sari Ratna Ningrum

Pendahuluan. Orang dewasa biasanya mulai memasuki masa lansia sehingga terjadi penurunankemampuan fungsional tubuh akibat proses degeneratif terutama pada penjahit dikarenakan posisikerja yang tidak ergonimis dalam jangka waktu yang lama sehingga rentang terkena penyakit lowback pain myogenic. Tujuan Penelitian ini bertujuan untuk mengetahui pengaruh pemberianwilliam’s flexion exercisedanmckenzie exerciseterhadap peningkatan aktivitas fungsional. william’s flexion exercise Metode. Penelitian ini menggunakan metode QuasiExperimental dengan pre and post two groupdesign. Sebanyak 28 sampel yang ditentukan dengan menggunakan teknik purposive sampling.Sampel dibagi menjadi 2 kelompok yaitu kelompk 1 dengan perlakuan william’s flexion exercise dankelompok 2 dengan perlakuanmckenzie exercise . Latihan dilakukan selama 4 minggu denganfrekuensi latihan selama 3 kali dalam seminggu baik untuk william’s flexion exercise maupunmckenzie exercise. Alat ukur yang di gunakan Oswesty Disability Index (ODI). Teknik analisa datayang digunakan adalah paired sample T-Testuntuk hipotesis I dan II dan Independent sample T-Testuntuk hipotesis III karena data berdistribusi normal.Hasil. Hasil uji hipotesis I menggunakan Paired Sample T-test diperoleh nilai p=0,000 ( p<0,05) danhasil uji hipotesis II menggunakan Paired Sample t-testdiperoleh nilai p=0,002(p<0,05) yang berartibahwa kedua perlakuan memiliki pengaruh terhadap peningkatan keseimbangan dinamis lansia padamasing-masing kelompok. Hasil hipotesis III menggunakan Independent Sample T-test diperolehnilaip=0,503(p>0,05)yang berarti tidak ada perbedaan pengaruh pemberian intervensi william’sflexion exercisedanmckenzie exercise terhadap peningkatan aktivits fungsional.Kesimpulan. Tidak ada perbedaan pengaruh william’s flexion exercise danmckenzie exercise terhadappeningkatan aktivitas fungsional. Penelitian selanjutnya harus lebih memperhatikan berbagai faktoryang dapat mengganggu aktivitas fungsional danmengontrol aktivitas yang dilakukan oleh respondendalam keseharian, diluar waktu pemberian intervensi.Kata Kunci : William’s flexion exercise,mckenzie exercise, Aktivitas Fungsional,Pembatik, Oswestry Disability Index(ODI).


Author(s):  
Okwuoma C Abanobi ◽  
Gabriel O Ayeni ◽  
Clifford C Ezeugwu ◽  
Oluwasegun A Ayeni
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