This chapter describes the natural sources that produce background levels of chemical contaminants in environmental media and the generally much larger anthropogenic sources in terms of: primary releases; and secondary sources resulting from chemical reactions within environmental media. There are primary sources within residences (personal care products, pesticides, the smoking of cigarettes, and unvented kitchen and bathroom effluents and heaters), in and around communities (furnace, power plant, and motor vehicle effluents), and effluents from industrial and commercial activities. Secondary sources include reactions between primary pollutants and natural and anthropogenic components in the atmosphere, hydrosphere, and lithosphere.