scholarly journals Clinical Significance of Health Status Assessment Measures in Head and Neck Cancer

2004 ◽  
Vol 130 (7) ◽  
pp. 825 ◽  
Author(s):  
Gerry F. Funk ◽  
Lucy H. Karnell ◽  
Russell B. Smith ◽  
Alan J. Christensen
Keyword(s):  
Head And Neck Cancer ◽  
Health Status ◽  
Head And Neck ◽  
Clinical Significance ◽  
Neck Cancer ◽  
Health Status Assessment ◽  
Status Assessment ◽  
Assessment Measures

scholarly journals Clinical significance of tumor-stroma ratio in head and neck cancer: a systematic review and meta-analysis

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alhadi Almangush ◽  
Rasheed Omobolaji Alabi ◽  
Giuseppe Troiano ◽  
Ricardo D. Coletta ◽  
Tuula Salo ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Clinical Significance ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Disease Free Survival ◽  
Tumor Stroma ◽  
Free Survival ◽  
Hematoxylin And Eosin ◽  
Meta Analyses

Abstract Background The clinical significance of tumor-stroma ratio (TSR) has been examined in many tumors. Here we systematically reviewed all studies that evaluated TSR in head and neck cancer. Methods Four databases (Scopus, Medline, PubMed and Web of Science) were searched using the term tumo(u)r-stroma ratio. The preferred reporting items for systematic reviews and meta-analyses (PRISMA) were followed. Results TSR was studied in nine studies of different subsites (including cohorts of nasopharyngeal, oral, laryngeal and pharyngeal carcinomas). In all studies, TSR was evaluated using hematoxylin and eosin staining. Classifying tumors based on TSR seems to allow for identification of high-risk cases. In oral cancer, specifically, our meta-analysis showed that TSR is significantly associated with both cancer-related mortality (HR 2.10, 95%CI 1.56–2.84) and disease-free survival (HR 1.84, 95%CI 1.38–2.46). Conclusions The assessment of TSR has a promising prognostic value and can be implemented with minimum efforts in routine head and neck pathology.

Antibody responses to survivin and their clinical significance in patients with head and neck cancer

Head & Neck ◽  
2007 ◽  
Vol 29 (12) ◽  
pp. 1128-1135 ◽  
Author(s):  
Mayumi Eto ◽  
Satoru Kodama ◽  
Naoki Uemura ◽  
Masashi Suzuki
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Clinical Significance ◽  
Neck Cancer ◽  
Antibody Responses

scholarly journals Management of radiation therapy-induced mucositis in head and neck cancer patients. Part I: Clinical significance, pathophysiology and prevention

2011 ◽  
pp. 102-113
Author(s):  
Wei Cheong Ngeow ◽  
Wen Lin Chai ◽  
Rosnah Binti Zain
Keyword(s):  
Radiation Therapy ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Neck Cancer ◽  
Neck Region ◽  
Clinical Problem ◽  
Important Clinical Problem ◽  
Oropharyngeal Mucositis

Oropharyngeal mucositis is the acute inflammatory and ulcerative reaction of the oral mucosa following radiation therapy to the head and neck region. It is such a common problem that nearly all head and neck cancer patients develop some degree of mucositis. This complication is usually transient in nature but it also represents an important clinical problem as it is a painful, debilitating, dose-dependent side effect for which there is no widely acceptable prophylaxis or effective treatment. As several authoritative groups have recently either undertaken systematic reviews or issued guidelines on the management of mucositis, it is the aim of this review to provide instead an overview of all the possible remedies available, as well as highlighting to researchers the gaps that need to be filled. The first part of this review outlines the clinical significance and pathophysiology of radiation-induced mucositis, and looks into some of the preventive approaches available.

Sign in / Sign up

Export Citation Format

Share Document