Early diagnosis of hydatidiform mole by ultrasound imaging

Hydatidiform mole belongs to the spectrum of gestational trophoblastic disorders in which abnormal conception leads to excess placental tissue formation in the absence of fetal development. The incidence of hydatidiform mole is quite rare so that not all experienced clinicians handle this case in clinical experience. Therefore, we present a case of hydatidiform mole in an adolescent patient. A 14-year-old primigravida woman, unemployed, with elementary school education, with a gestational age of 16 weeks went to the ER with complaints of vaginal bleeding for 2 days. Physical examination found the fundal height at umbilicus, abdominal tenderness, accompanied by vaginal bloody discharge. Complete blood count found mild normochromic anemia with increased levels of T3 and decreased TSH. Ultrasound imaging found a typical vesicular pattern of a hydatidiform mole. Treatment of molar evacuation by curettage and drainage was carried out one day after presentation and obtained 600 grams of molar tissue. The patient underwent 24 hours of post-operative observation before being discharged in a stable state. The patient presented with a typical clinical appearance of hydatidiform mole. Ultrasound imaging reveals a typical complete hydatidiform mole accompanied by anemia and hyperthyroxinemic which may accompany hydatidiform mole. Evacuation was carried out according to clinical guidelines and the patient was discharged in a good condition.

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COMORBIDADES ASSOCIADAS A MOLA HIDATIFORME: COMO DIAGNOSTICAR E TRATAR

Revista de Patologia do Tocantins ◽

10.20873/uft.2446-6492.2018v5n3p68 ◽

2018 ◽

Vol 5 (3) ◽

pp. 68-74

Author(s):

Isabela Borges Corrêa ◽

Mariana Rocha Machado de Carvalho ◽

Nayara Pettine Dias Soares ◽

Hanna Helena Lopes ◽

Luciana Zenóbio Quadra Vieira dos Santos

Keyword(s):

Early Diagnosis ◽

Hydatidiform Mole ◽

First Trimester ◽

Gestational Trophoblastic Disease ◽

Diagnosis And Treatment ◽

Uterine Perforation ◽

Vacuum Aspiration ◽

De Se ◽

Aspiration Technique ◽

Life Threatening

RESUMO A mola hidatiforme é uma forma benigna da doença trofoblástica gestacional pouco frequente na gravidez e com potencial para evoluir para formas que necessitam de tratamento sistêmico e podem ameaçar a vida. As apresentações com molas de grande volume, com eliminação de vesículas e anemia, são cada vez menos frequentes devido ao uso sistemático de ultrassonografia gestacional no primeiro trimestre de gestação que permite o diagnóstico precoce. Ainda assim, raramente podem ocorrer certas complicações, como hemorragia, hipertireoidismo, pré-eclâmpsia, insuficiência respiratória e cistos ovarianos, que exigem conduta imediata e encaminhamento das pacientes para centro de referências que realizem aspiração uterina, preferencialmente, pela técnica de vácuo-aspiração, a fim de se evitar possíveis intercorrências, dentre as quais a perfuração uterina. Deve ser realizado seguimento rigoroso, sistemático e pontual para diagnóstico precoce de NTG e preservação da fertilidade das mulheres acometidas. Enfatizar os métodos de diagnóstico e tratamento das principais comorbidades associadas a mola hidatiforme é o objetivo deste estudo, que foi realizado através de uma revisão de literatura , utilizando artigos dos últimos 15 anos, nacionais e internacionais arquivados nos bancos de dados MEDLINE, BIREME, PUBMED, SciELO e Livros periódicos analisados nas biblioteca do Instituto Presidente Antônio Carlos. Palavras-chave: Comorbidades associadas a gravidez molar. Mola hidatiforme – diagnóstico e tratamento. Neoplasia trofoblástica gestacional. ABSTRACT A hydatidiform mole is a benign form of infrequent gestational trophoblastic disease in pregnancy and it has the potential to evolve into forms that require systemic treatment and can be life-threatening. Presentations with large amounts of moles, with elimination of vesicles and anemia, are becoming less frequent due to the systematic use of gestational ultrasound in the first trimester of pregnancy that allows early diagnosis. Still, it could rarely occur certain complications, such as bleeding, hyperthyroidism, preeclampsia, respiratory failure and ovarian cysts, requiring immediate management and referral to the center of reference to perform a uterine aspiration, preferably by vacuum aspiration technique, in order to avoid possible complications, among them uterine perforation. It should be rigorous systematic and timely followed, for early diagnosis of NTG and preservation of affected women’s fertility. This paper aims to emphasize the methods of diagnosis and treatment of major comorbidities associated with hydatidiform mole. This course conclusion work was done through a literature review, using articles from the last 15 years, national and international, using the databases MEDLINE, BIREME, PUBMED, SciELO and periodicals Books analyzed in the library of the Instituto Presidente Antonio Carlos. Keywords: Comorbidities associated with molar pregnancy. Hydatidiform mole - Diagnosis and Treatment. Neoplasia gestational trophoblastic.

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Analysis and Evaluation of Ultrasound Imaging Features and Pathological Results of Ovarian Cancer

Journal of Medical Imaging and Health Informatics ◽

10.1166/jmihi.2021.3349 ◽

2021 ◽

Vol 11 (3) ◽

pp. 981-987

Author(s):

Yuqing Zhang ◽

Yan Li ◽

Mei Wu ◽

Feixue Zhang ◽

Guangrui Shao ◽

...

Keyword(s):

Ovarian Cancer ◽

Early Diagnosis ◽

Cancer Patients ◽

Ultrasound Imaging ◽

Malignant Tumors ◽

Maximum Diameter ◽

Pathological Examination ◽

Imaging Features ◽

Specificity And Sensitivity ◽

Different Ages

To compare and analyze the relationship between the characteristics of ultrasound images of ovarian cancer and the results of postoperative pathological examination. A retrospective analysis of 206 patients with suspected ovarian cancer confirmed by surgical pathology was taken as the research object. The location, size, morphology, partition and wall nodules, cystic solidity, and signal characteristics of the tumor were observed and compared with the results of postoperative pathological examination evaluation and analysis to improve the early clinical diagnosis of ovarian cancer patients. By regression analysis of the histological examination of patients with ovarian tumors of different ages and the proportion of cox postoperative recurrence risk regression models, 154 of 206 ovarian tumor patients were ovarian cancer. There were significant differences in pathological types, lesion locations, maximum diameter lengths, and internal echo in patients with ovarian malignant tumors at different ages (p < 0.05). Ultrasound of ovarian cancer shows that the tumor has large tumor body, strong echo, cyst wall has protrusions, and peripheral and internal blood flow that is mainly high-speed and low-resistance. The sensitivity, specificity, and accuracy of ultrasound for ovarian cancer diagnosis are 84.38%, 66.67%, 81.01%. The accuracy, specificity, and sensitivity of early diagnosis of clinical ovarian cancer patients by ultrasound imaging features provide sufficient imaging evidence to further promote the clinical judgment of benign and malignant tumors, which is beneficial to doctors’ clinical treatment of ovarian cancer patients. The early diagnosis and the higher clinical value were shown.

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