1-Ethyl-3-(3′-dimethylaminopropyl)carbodiimide Hydrochloride

2017 ◽  
pp. 1-5
Author(s):  
Richard S. Pottorf ◽  
Peter Szeto ◽  
Madduri Srinivasarao
Keyword(s):  
Carbodiimide Hydrochloride

Enhancing the Strength of the Tendon–Suture Interface Using 1-Ethyl-3-(3-Dimethylaminopropyl) Carbodiimide Hydrochloride and Cyanoacrylate

2007 ◽  
Vol 32 (5) ◽  
pp. 606-611 ◽  
Author(s):  
Chunfeng Zhao ◽  
Yu-Long Sun ◽  
Mark E. Zobitz ◽  
Kai-Nan An ◽  
Peter C. Amadio
Keyword(s):  
Tendon Suture ◽  
Carbodiimide Hydrochloride

scholarly journals The effect of two cross-linking agents on dentin bond strength of resin-modified glass ionomer

2017 ◽  
Vol 11 (04) ◽  
pp. 486-490
Author(s):  
Fereshteh Shafiei ◽  
Maryam Firouzmandi ◽  
Moona Zamanpour
Keyword(s):  
Bond Strength ◽  
Shear Bond Strength ◽  
Analysis Data ◽  
Test Results ◽  
Glass Ionomer ◽  
Medium Term ◽  
Hybrid Layer ◽  
Carbodiimide Hydrochloride ◽  
Resin Modified Glass Ionomer ◽  
One Way Anova

ABSTRACT Objectives: The hybrid layer at the interface of resin-modified glass ionomer cements and dentin is prone to degradation by endogenous matrix metalloproteinases. We aimed to investigate the effect of two types of collagen crosslinkers, carbodiimide and proanthocyanidin (PA), on immediate and medium-term bond strength of a resin-modified glass ionomer to dentin. Materials and Methods: Seventy-two molars were flattened on the occlusal surface to expose dentin. The specimens were divided into control, 1-ethyl-3-(3-dimethylaminopropy) carbodiimide hydrochloride (EDC), and PA groups (n = 24). In the EDC and PA groups, carbodiimide and PA solutions were applied for 1 min, respectively. Resin-modified glass ionomer was bonded. Half of the specimens in each group were tested for shear bond strength after 24 h and the other half were tested after 6 months. Statistical Analysis: Data were analyzed with SPSS version 16 (SPSS Inc, Chicago, IL, USA), using two-way ANOVA, and subgroup analysis was performed using one-way ANOVA, Tukey's test, and t-test. Results: Two-way ANOVA showed that treatment and time affected the bond strength. Carbodiimide and PA did not affect the immediate bond strength (P = 0.51). After 6 months, the bond strength of the EDC group was significantly lower than that of the control and PA groups. Bond strength of the control and PA groups increased after 6 months (P ≤ 0.002). Conclusion: PA did not interfere with maturation of RMGIC unlike carbodiimide. Therefore, it can be suggested as an matrix metalloproteinase inhibitor before bonding of resin-modified glass ionomer to dentin.

scholarly journals STUDY OF EDC/NHS IMMOBILIZATION FOR PLUMBOUS DETECTION USING SURFACE PLASMON RESONANCE

2016 ◽  
Vol 78 (3) ◽  
Author(s):  
Ali Abdulkhaleq Alwahib ◽  
A. R. Sadrolhosseini ◽  
H. N. Lim ◽  
M. H. Yaacob ◽  
M. H. Abu Bakar ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
The United States ◽  
Environment Protection ◽  
Protection Agency ◽  
Resonance Technique ◽  
Heavy Metal Detection ◽  
Carbodiimide Hydrochloride

The presence of plumbous (Pb2+) in Irrigation water is harmful for the environment as well as human health. Herein, a simple yet effective sensor for Pb2+ detection is presented utilizing a surface plasmon resonance technique. The proposed sensor consists of a combination of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) were attached to a gold layer offers a new option for heavy metal detection. The EDC/NHS works as a sensing layer that able to detect Pb2+ down to 15 ppm that matches with the United States Environment Protection Agency. 

Δ9-Tetrahydrocannabinol–Protein Conjugates

1974 ◽  
Vol 52 (3) ◽  
pp. 252-258 ◽  
Author(s):  
P. T. Tsui ◽  
K. A. Kelly ◽  
M. M. Ponpipom ◽  
M. Strahilevitz ◽  
A. H. Sehon
Keyword(s):  
Water Soluble ◽  
Protein Conjugates ◽  
Carbodiimide Hydrochloride ◽  
Derivatives Of

The syntheses of four distinct derivatives of Δ9-tetrahydrocannabinol (Δ9-THC), intended for subsequent coupling to proteins and for use as hapten–protein conjugates for the production of anti-THC antibodies, are described. Three of these THC derivatives were coupled to proteins with the aid of the water-soluble carbodiimide, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride, and the fourth in the form of THC-isocyanate was conjugated directly to proteins.

Development of Biocompatible Glues for Minimum Invasive Therapy

2007 ◽  
Vol 330-332 ◽  
pp. 1339-1342 ◽  
Author(s):  
Tetsushi Taguchi ◽  
H. Saito ◽  
Masashi Iwasashi ◽  
Masataka Sakane ◽  
S. Kakinoki ◽  
...  
Keyword(s):  
Citric Acid ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fibrin Glue ◽  
Acid Derivative ◽  
Bonding Strength ◽  
Wound Closure ◽  
Mouse Skin ◽  
Carbodiimide Hydrochloride

A biocompatible glue consisting of human serum albumin (HSA) and citric acid derivative (CAD), named CAD-A glue was developed. CAD was successfully synthesized by the reaction between citric acid and N-hydroxysuccinimide in the presence of 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hydrochloride. When the CAD-A glue was applied to the collagenbased casings, it took 7 min to obtain half of maximum bonding strength (760 g/cm2). The bonding strength of this glue to collagen-based casings increased with increasing of HSA concentration.The bonding strength of CAD-A glue increased with increasing CAD concentration up to 200 mM, and then decreased with increasing CAD concentration under the fixed HSA concentration (50 w/w%). The CAD-A glue showed excellent wound closure ability rather than fibrin glue when applied to the mouse skin. These results suggested that this developed glue had both tissue compatibility and bonding strength for use in clinical field.

Investigation of Synthesis Parameters for Modification of Chitosan with Enrofloxacin

2015 ◽  
Vol 659 ◽  
pp. 436-440
Author(s):  
Saniwan Srithongkham ◽  
Piyawadee Sutcharee ◽  
Amornrat Lertworasirikul
Keyword(s):  
Reaction Times ◽  
Coupling Agents ◽  
Amino Group ◽  
Synthesis Conditions ◽  
E Coli ◽  
Chemical Structures ◽  
Optimum Synthesis ◽  
Carbodiimide Hydrochloride ◽  
Synthesis Parameters ◽  
Ft Ir

This research aims to investigate synthesis parameters for modification of chitosan with enrofloxacin. Most modifications of chitosan are focused on amino group. There are many methods for modification of chitosan, for example, conjugation of amino group with carboxylic group by coupling agents. 1-Ethyl-3-(3-(dimethylamino) propyl) carbodiimide hydrochloride (WSC) andN-hydroxysuccinimide (NHS) are widely used coupling agents for amide formation under mild conditions. Those two coupling agents were applied in this study. Optimum amount and ratio of coupling agents, amount of enrofloxacin and reaction times were investigated. The chemical structures were characterized by Fourier transform infrared spectroscopy (FT-IR). The optimum synthesis conditions were determined from the absorbance ratios. Chitosan-enrofloxacin has antibacterial activity against bothS. aureusandE. coli.

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