Systemic antibiotics as adjunctive treatment for chronic periodontitis

2005 ◽  
Author(s):  
Arianna Cazzaniga ◽  
Carlo Galli ◽  
Alessandro Fiorini ◽  
Eleonora Cantini ◽  
Giovanni Lodi
Keyword(s):  
Chronic Periodontitis ◽  
Adjunctive Treatment ◽  
Systemic Antibiotics

Optimization of the terms of supportive periodontal therapy using photoactivated disinfection

2019 ◽  
Vol 24 (2) ◽  
pp. 121-126 ◽  
Author(s):  
V. G. Atrushkevich ◽  
L. Yu. Orekhova ◽  
O. O. Yanushevich ◽  
E. Yu. Sokolova ◽  
E. S. Loboda
Keyword(s):  
Chronic Periodontitis ◽  
Adjunctive Treatment ◽  
Control Group ◽  
Clinical Parameters ◽  
Ozone Therapy ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Supportive Periodontal Therapy ◽  
Tannerella Forsythensis ◽  
Observation Period

Relevance: to indentify if periodontal treatment which is presented by photoactivated disinfection (PAD) adjunctively to scaling and root planing (SRP) yield better outcomes than ozone therapy as an adjunct to SRP in periodontitis.Materials and methods: we examined 57 (mean age 49,3 ± 1,02) patients with chronic periodontitis, divided into groups, SRP + PAD, SRP + ozone therapy and SRP alone. Subgingival plaque samples were subjected to DNA extraction and real time PCR amplifcation for detection Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi), Tannerella forsythensis (Tf), Treponema denticola (Td), Aggregatibacter actinomycetemcomitans (Aa). The amount of periodontopathogens and clinical parameters including plaque index, clinical attachment loss, pocket depth, bleeding on probing were measured at baseline, after 40, 90 and 180 days.Results: the results in groups of PAD+SRP and ozone therapy+SRP showed an improvement in all clinical parameters PI, BOP, PD, CAL and the quantity of Pg, Td and Tf compared to the control group during an observation period.Conclusion: the results showed additional benefts from PAD and ozone therapy as an adjunctive treatment to SRP for patients of chronic periodontitis.

scholarly journals In vivo investigation of diode laser application on red complex bacteria in non-surgical periodontal therapy: a split-mouth randomised control trial

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Suné Mulder-van Staden ◽  
Haly Holmes ◽  
Jos Hille
Keyword(s):  
Diode Laser ◽  
Chronic Periodontitis ◽  
Continuous Wave ◽  
Periodontal Therapy ◽  
Adjunctive Treatment ◽  
Randomised Control Trial ◽  
Clinical Parameters ◽  
Laser Application ◽  
Bleeding On Probing ◽  
Test Side

AbstractAssessment of the efficacy of a single 810 nm diode laser application as an adjunctive treatment modality during the first intervention of non-surgical periodontal therapy (NPT). 25 patients diagnosed with chronic periodontitis underwent a split-mouth randomised control trial. The periodontal pockets of the test quadrants were treated with an 810 nm diode laser as an adjunct to NPT (Picasso GaAlAs; AMD Lasers). The laser was set at 1.0 W continuous wave, 400 µm tip, 796 W/cm2 peak power density and a 32 J/cm2 energy density. Therapeutic outcomes were evaluated based on the clinical parameters, which included probing pocket depth, recession, clinical attachment level, full mouth plaque score, full mouth bleeding on probing and tooth mobility. The baseline bacterial collection was completed from the periodontal pockets and then re-evaluated at 6 weeks. Clinical parameters demonstrated no statistical difference, with the exception of a statistically significant (P < 0.05) reduction in bleeding on probing for the test side. The test side resulted in a statistical increase of Capnocytophagaspecies and Treponemadenticola. The single application of the diode laser did not significantly improve the bacterial nor the clinical parameters in patients with chronic periodontitis.Trial registration number: PACTR201909915338276.

scholarly journals Role of sea buckthorn oil in management of chronic periodontitis: follow-up study

2016 ◽  
Vol 4 (2) ◽  
pp. 33 ◽  
Author(s):  
Anamika Sharma ◽  
Shatakshi Sharma ◽  
Shivi Khattri ◽  
Harshita Garg
Keyword(s):  
Chronic Periodontitis ◽  
Periodontal Ligament ◽  
Alveolar Bone ◽  
Sea Buckthorn ◽  
Long Term Results ◽  
Treatment Modalities ◽  
Adjunctive Treatment ◽  
Scaling And Root Planing ◽  
Root Planing ◽  
Sea Buckthorn Oil

Periodontitis is an inflammatory condition resulting in loss of periodontal ligament and alveolar bone. Nonsurgical therapy remains the cornerstone of periodontal treatment. For sustained plaque control it plays an important role in achieving successful long-term results for the care of Chronic Periodontitis subjects. Proper maintenance and patient hygiene plays a vital role in suppression of re-colonization of micro-organism. Many adjunctive treatment modalities along with mechanical debridement have been clinically used and investigated for their efficacy. Systemic antioxidants in conjunction with scaling and root planing can offer additional effects and can be used as an adjunctive treatment. Patients with periodontal disease display increased PMN number and activity, resulting in high degree of free radical release culminating in heightened oxidative damage to gingival tissues, periodontal ligament and alveolar bone. Damage mediated by free radicals can be mitigated by "antioxidant defense system ".Sea buckthorn oil is an omega-7 fatty acid antioxidant which has unique botanical and nutritional properties thereby benefiting mucous membrane by reducing inflammation, improving wound healing and showing excellent antibacterial property. In this research patients were prescribed systemic antioxidant after the phase 1 therapy ie scaling and root planing to observe its effects on the various clinical parameters.

Unusual Findings in Trials Evaluating Adjuncts to Scaling and Root Planing: Meta-analysis (Part 1)

2021 ◽  
pp. 238008442110397
Author(s):  
J.C. Gunsolley ◽  
K. Al-Abedalla ◽  
M. Shaqman ◽  
E. Ioannidou
Keyword(s):  
Effect Size ◽  
Research Group ◽  
Meta Analysis ◽  
Adjunctive Treatment ◽  
Clear Explanation ◽  
The Government ◽  
Mo Effect ◽  
Systemic Antibiotics ◽  
Root Planning ◽  
Scaling And Root Planning

Background: A number of studies in patients with periodontitis have compared scaling and root planning (SRP) combined with an adjunctive treatment to SRP alone. Within that literature, an array of studies with overlapping investigators has consistently yielded substantially greater effects of adjunctive treatments than had been previously noted. This report investigates discrepancies between that cluster of research and the most recent American Dental Association (ADA) systematic review. Methods: This review was preregistered at https://osf.io/4meyd/ . A search using the Scopus platform identified 32 articles published from 2010 to 2017 by investigators affiliated with the Government Dental College and Research Institute (GDCRI) in Bangalore, India. The primary outcome used in this meta-analysis was the change in clinical attachment level (CAL) after 6 mo. Effect sizes were estimated using Comprehensive Meta-Analysis software after categorizing agents into groups based on pharmacologic similarity. Results: The search identified 32 studies encompassing 5 sets of adjunctive agents. Across the GDCRI studies, the CAL averaged 1.67 mm (95% confidence interval [CI]: 1.43–1.91 mm), substantially exceeding values reported in the ADA review (mean: 0.39 mm, 95% CI: 0.27–0.51 mm). For categories of studies in which comparable subgroup estimates were available, the evaluations yielded overlapping estimates of SRP alone, but CAL estimates were discrepant for both locally delivered antimicrobials (GDCRI studies: mean: 1.45 mm, 95% CI: 0.63–2.27 mm; ADA review: mean: 0.38 mm, 95% CI: 0.16 –0.60 mm) and systemic antibiotics (GDCRI studies: mean: 1.35 mm, 95% CI: 0.97–1.73 mm; ADA review: mean: 0.39 mm, 95% CI: 0.21–0.57 mm). Conclusion: In the literature on adjunctive agents supplementing SRP, findings from investigators linked to GDCRI stand out as having significantly more favorable estimated effects. Meanwhile, some agents studied by GDCRI-linked investigators have not been investigated by other researchers. In the absence of a clear explanation for discrepant results, it is recommended that unusually favorable reported effects of adjunctive agents be viewed with caution. Knowledge Transfer Statement: The present meta-analysis observed an unusually large effect size of adjunctive agents to scaling and root planning in studies conducted by the same research group. These results were not consistent with trials on adjunctive agents and previous reports. As this research group has exclusively tested most of the agents, their results must be viewed with caution until other independent groups replicate the studies and reproduce the effect size.

Sign in / Sign up

Export Citation Format

Share Document