Studies of the Formation and Absorption of the Cerebrospinal Fluid Using Radioactive Isotopes: A Critical Evaluation of Data and Conclusions

Author(s):  
B. Selverstone
2019 ◽  
Vol 16 (159) ◽  
pp. 20190572 ◽  
Author(s):  
John H. Thomas

The flow of cerebrospinal fluid along perivascular spaces (PVSs) is an important part of the brain’s system for delivering nutrients and eliminating metabolic waste products (such as amyloid-β); it also offers a pathway for the delivery of therapeutic drugs to the brain parenchyma. Recent experimental results have resolved several important questions about this flow, setting the stage for advances in our understanding of its fluid dynamics. This review summarizes the new experimental evidence and provides a critical evaluation of previous fluid-dynamic models of flows in PVSs. The review also discusses some basic fluid-dynamic concepts relevant to these flows, including the combined effects of diffusion and advection in clearing solutes from the brain.


1977 ◽  
Vol 35 ◽  
pp. 295-316
Author(s):  
G. A. Wilkins

SummaryThis report summarises the discussions on the topics of the five invited papers, and on other matters of general interest that were raised by the contributed papers. The principal headings are: standards for datafiles; the influence of acquisition and processing techniques; the critical evaluation of data; the designation of astronomical objects; the distribution of data; survey of facilities; the future role of data centres; and recommendations on IAU activities.


2012 ◽  
Vol 18 (2) ◽  
pp. 229-230
Author(s):  
P. Humaidan ◽  
S. Kol ◽  
C. Benadiva ◽  
L. Engmann ◽  
E.G. Papanikolaou

2021 ◽  
Vol 11 (10) ◽  
pp. 610
Author(s):  
Csaba Csapodi ◽  
Miklós Hoffmann

The new National Core Curriculum came into force in September 2020 in Hungarian schools. The COVID-19 pandemic has had a deep impact on the final stages of its development. In this paper we have selected two areas for analysis: the fundamental principles of mathematics curriculum and the matriculation exam in mathematics. We propose improvements in both fields, further emphasizing the importance of skills in displaying, understanding and processing information, including visual information obtained as a source or outcome of a problem. We argue that representation, interpretation, and critical evaluation of data and information must be essential parts of the mathematics curriculum. In this context, we also propose a new type of task for the matriculation exam: a complex essay task. The ultimate goal is the development of cross-cutting competencies to support students to become citizens who can make responsible decisions based on the data and knowledge available.


Author(s):  
Omatseye Alero Akuirene ◽  
Josiah O. Adjene ◽  
Nkemdilim I. Obi ◽  
Ezekiel Uba Nwose

<p class="abstract"><strong>Background:</strong> The impact of gas flaring in Ubeji metropolis, relative to other communities of Delta is of interest. This study assessed the environmental impact of gas flaring in Ubeji metropolis of Delta State. The objective of this study is to study the comparative assessment of the environmental impacts of gas flaring on five communities of unequal distance from gas flaring site.</p><p class="abstract"><strong>Methods:</strong> Questionnaire survey was used to evaluate three research questions that included the level of knowledge in the survey communities regarding health impact of gas flaring; prevalence level of assessed health conditions in Ubeji metropolis relative to communities farther from or nearer to Warri gas flaring site; and perceived impact of gas flaring on air quality indicated by health and environmental toxicity indices.  </p><p class="abstract"><strong>Results:</strong> Descriptive evaluation of data shows Ubeji appears to have the highest proportion of persons suffering respiratory problems, but the figure for family members is less than some other communities. The respondents nearer flaring site show more awareness compared to those farther away. Critical evaluation showed no directional change in prevalence of disease linked to gas flaring. There is linear relationship between ‘distance to gas flare site’ and ‘toxic impact on air quality’.</p><p class="abstract"><strong>Conclusions:</strong> This report submits further data to the discourse that, on the basis of nearness to gas flaring site, there is significant difference between communities experience of environmental and health impact.</p><p> </p>


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