scholarly journals Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles

2018 ◽  
Vol 30 (27) ◽  
pp. 1800512 ◽  
Author(s):  
Jinyoung Kang ◽  
Dokyoung Kim ◽  
Junxin Wang ◽  
Yunho Han ◽  
Jonathan M. Zuidema ◽  
...  
Keyword(s):  
Silicon Nanoparticles ◽  
Photoacoustic Imaging ◽  
Imaging Agent ◽  
Mesoporous Silicon

scholarly journals Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles

2019 ◽  
Vol 31 (41) ◽  
pp. 1905454
Author(s):  
Jinyoung Kang ◽  
Dokyoung Kim ◽  
Junxin Wang ◽  
Yunho Han ◽  
Jonathan M. Zuidema ◽  
...  
Keyword(s):  
Silicon Nanoparticles ◽  
Photoacoustic Imaging ◽  
Imaging Agent ◽  
Mesoporous Silicon

Photocatalytic hydrogen generation using mesoporous silicon nanoparticles: influence of magnesiothermic reduction conditions and nanoparticle aging on the catalytic activity

Nanoscale ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 2685-2692
Author(s):  
Isabel S. Curtis ◽  
Ryan J. Wills ◽  
Mita Dasog
Keyword(s):  
Catalytic Activity ◽  
Hydrogen Production ◽  
Silicon Nanoparticles ◽  
Hydrogen Generation ◽  
Oxide Content ◽  
Magnesiothermic Reduction ◽  
Mesoporous Silicon ◽  
High Crystallinity ◽  
Photocatalytic Hydrogen Generation

High crystallinity, low oxide content, and low sintering lead to optimally performing mesoporous Si photocatalysts for solar-driven hydrogen production.

Small highly mesoporous silicon nanoparticles for high performance lithium ion based energy storage

2020 ◽  
Vol 400 ◽  
pp. 125958
Author(s):  
Yen-Ju Wu ◽  
Yu-An Chen ◽  
Chun-Lung Huang ◽  
Jing-Ting Su ◽  
Cheng-Ting Hsieh ◽  
...  
Keyword(s):  
Energy Storage ◽  
High Performance ◽  
Silicon Nanoparticles ◽  
Lithium Ion ◽  
Mesoporous Silicon

scholarly journals Cavitation Induced by Janus-Like Mesoporous Silicon Nanoparticles Enhances Ultrasound Hyperthermia

2019 ◽  
Vol 7 ◽  
Author(s):  
Andrey Sviridov ◽  
Konstantin Tamarov ◽  
Ivan Fesenko ◽  
Wujun Xu ◽  
Valery Andreev ◽  
...  
Keyword(s):  
Silicon Nanoparticles ◽  
Mesoporous Silicon ◽  
Ultrasound Hyperthermia

scholarly journals Magnetically-Targeted Nanoparticle-Guided M2 Macrophage Polarization For Fracture Healing Promotion

2021 ◽  
Author(s):  
Wu Zhou ◽  
Ze Lin ◽  
Yuan Xiong ◽  
Hang Xue ◽  
Wen Song ◽  
...  
Keyword(s):  
Fracture Healing ◽  
Osteogenic Differentiation ◽  
Silicon Nanoparticles ◽  
Macrophage Polarization ◽  
Osteoblastic Differentiation ◽  
Fracture Site ◽  
M2 Macrophage ◽  
Mesoporous Silicon ◽  
M2 Macrophage Polarization ◽  
M2 Phenotype

Abstract Background: Macrophages are essential for fracture healing, acting mainly through remodeling of the extracellular matrix and promotion of angiogenesis. The role of macrophages in regulating osteogenic differentiation, particularly that of the M2 phenotype, is increasingly researched. Baicalein (BCL) had also been shown to have pro-fracture-healing effects.Results: In this study, we developed mesoporous silica and Fe3O4 composite-targeted nanoparticles loaded with BCL (BCL@MMSNPs-SS-CD-NW), that could be magnetically delivered to the fracture site. These induced macrophage recruitment in a targeted manner, polarizing them towards the M2 phenotype, and thereby inducing MSCs towards osteoblastic differentiation. The mesoporous silicon nanoparticles (MSNs) were prepared with surface sulfhydrylation and amination modification, and the mesoporous channels were blocked with β-cyclodextrin. The outer layer of the mesoporous silicon was added with an amantane-modified NW targeting peptide to obtain the targeted nano-system. After entering macrophages, BCL could be released from nanoparticles since the disulfide linker could be cleaved by intracellular glutathione (GSH) resulting in the removing of CD gatekeeper, which is a key element in the pro-bone-remodeling functions, such as anti-inflammation and induction of M2 macrophage polarization to facilitate osteogenic differentiation.Conclusions: This nano-system passively accumulated in the fracture site, promoting osteogenic differentiation activities, highlighting a potent therapeutic benefit with high biosafety.

Improved production efficiency of mesoporous silicon nanoparticles by pulsed electrochemical etching

2016 ◽  
Vol 288 ◽  
pp. 360-365 ◽  
Author(s):  
Tuomo Nissinen ◽  
Timo Ikonen ◽  
Mejor Lama ◽  
Joakim Riikonen ◽  
Vesa-Pekka Lehto
Keyword(s):  
Production Efficiency ◽  
Silicon Nanoparticles ◽  
Electrochemical Etching ◽  
Mesoporous Silicon

Small interfering RNA delivery by polyethylenimine-functionalised porous silicon nanoparticles

2015 ◽  
Vol 3 (12) ◽  
pp. 1555-1565 ◽  
Author(s):  
M. Hasanzadeh Kafshgari ◽  
M. Alnakhli ◽  
B. Delalat ◽  
S. Apostolou ◽  
F. J. Harding ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Protein Expression ◽  
Resistance Gene ◽  
Small Interfering Rna ◽  
Silicon Nanoparticles ◽  
Chemotherapy Resistance ◽  
Glioblastoma Cells ◽  
Mesoporous Silicon ◽  
Porous Silicon Nanoparticles ◽  
Interfering Rna

Polyethyleneimine-coated mesoporous silicon nanoparticles efficiently deliver siRNA in glioblastoma cells, subsequently reducing the protein expression of a chemotherapy resistance gene by 70% within 72 hours.

Amine Surface Modifications and Fluorescent Labeling of Thermally Stabilized Mesoporous Silicon Nanoparticles

2012 ◽  
Vol 116 (42) ◽  
pp. 22307-22314 ◽  
Author(s):  
Wujun Xu ◽  
Joakim Riikonen ◽  
Tuomo Nissinen ◽  
Mika Suvanto ◽  
Kirsi Rilla ◽  
...  
Keyword(s):  
Silicon Nanoparticles ◽  
Surface Modifications ◽  
Fluorescent Labeling ◽  
Mesoporous Silicon

scholarly journals Stabilization of porous silicon nanoparticles by PEGalization in water

2021 ◽  
Vol 2058 (1) ◽  
pp. 012013
Author(s):  
A S Eremina ◽  
A Yu Kharin ◽  
Yu V Kargina ◽  
V Yu Timoshenko
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Scanning Electron Microscopy ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Ball Mill ◽  
Silicon Nanoparticles ◽  
Mechanical Grinding ◽  
Mesoporous Silicon ◽  
Scanning Electron

Abstract Mesoporous silicon (mPSi) nanoparticles (NPs) are stabilized by polyethylene glycol (PEG) chains during mechanical grinding in a ball mill that is used to form mPSi-PEG-NPs. The structure, composition, and properties of the obtained samples are studied by means of the dynamic light scattering, scanning electron microscopy and Fourier-transform infrared spectroscopy. The proposed PEGalization procedure is an effective way of regulating the dissolution of mPSi-NPs in water and it is promising for potential application of mPSi-NPs in drug delivery.

A smart off–on copper sulfide photoacoustic imaging agent based on amorphous–crystalline transition for cancer imaging

2018 ◽  
Vol 54 (78) ◽  
pp. 10962-10965 ◽  
Author(s):  
Qunfeng Feng ◽  
Yanjun Xu ◽  
Bing Hu ◽  
Lu An ◽  
Jiaomin Lin ◽  
...  
Keyword(s):  
Copper Sulfide ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Cancer Imaging ◽  
Low Cost ◽  
Infrared Region ◽  
Imaging Agent ◽  
Agent Based ◽  
Near Infrared Region

By exploiting the amorphous–crystalline transition of CuS, which results in greatly increased absorption throughout the entire near-infrared region, a novel smart off–on CuS photoacoustic imaging agent with good photostability and low cost is developed.

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