Intracranial pressure, conductance to cerebrospinal fluid outflow, and cerebral blood flow in patients with benign intracranial hypertension (pseudotumor cerebri)

1985 ◽  
Vol 17 (2) ◽  
pp. 158-162 ◽  
Author(s):  
F. Gjerris ◽  
P. Soelberg Sørensen ◽  
S. Vorstrup ◽  
O. B. Paulson
Keyword(s):  
Blood Flow ◽  
Cerebrospinal Fluid ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Benign Intracranial Hypertension

scholarly journals Cerebral Blood Flow in Low Intracranial Pressure Headaches—What Is Known?

2019 ◽  
Vol 10 (1) ◽  
pp. 2
Author(s):  
Magdalena Nowaczewska ◽  
Henryk Kaźmierczak
Keyword(s):  
Blood Flow ◽  
Cerebrospinal Fluid ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Intracranial Hypertension ◽  
Intracranial Hypotension ◽  
Csf Pressure ◽  
Cerebral Vasodilatation ◽  
The Relationship ◽  
The Brain

Headaches attributed to low cerebrospinal fluid (CSF) pressure are described as orthostatic headaches caused by spontaneous or secondary low CSF pressure or CSF leakages. Regardless of the cause, CFS leaks may lead to intracranial hypotension (IH) and influence cerebral blood flow (CBF). When CSF volume decreases, a compensative increase in intracranial blood volume and cerebral vasodilatation occurs. Sinking of the brain and traction on pain-sensitive structures are thought to be the causes of orthostatic headaches. Although there are many studies concerning CBF during intracranial hypertension, little is known about CBF characteristics during low intracranial pressure. The aim of this review is to examine the relationship between CBF, CSF, and intracranial pressure in headaches assigned to low CSF pressure.

scholarly journals Effects of Midazolam on Cerebral Hemodynamics and Cerebral Vasomotor Responsiveness to Carbon Dioxide

1983 ◽  
Vol 3 (2) ◽  
pp. 246-249 ◽  
Author(s):  
A. Forster ◽  
O. Juge ◽  
D. Morel
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Intracranial Hypertension ◽  
Cerebral Blood Volume ◽  
Water Soluble ◽  
Increased Intracranial Pressure ◽  
Beneficial Effects ◽  
The Mean

Although it is known that hypercarbia increases and benzodiazepines decrease cerebral blood flow (CBF), the effects of benzodiazepines on CBF responsiveness to CO2 are not well documented. The influence on CBF and CBF-C02 sensitivity of placebo or midazolam, which is a new water-soluble benzodiazepine, was measured in eight healthy volunteers using the noninvasive 133Xe inhalation method for CBF determination. Under normocarbia, midazolam decreased CBF from 40.6 ± 3.2 to 27.0 ± 5.0 ml 100 g−1 min−1 (x̄ ± SD). At a later session under hypercarbia, CBF was 58.8 ± 4.4 ml 100 g−1 min−1 after administration of placebo, and 49.1 ± 10.2 ml 100 g−1 min−1 after midazolam. The mean of the slopes correlating Paco2 and CBF was significantly steeper with midazolam (2.5 ± 1.2 ml 100 g−1 min−1 mm Hg−1) than with placebo (1.5 ± 0.4 ml 100 g−1 min−1 mm Hg−1). Our results suggest that midazolam may be a safe agent to use in patients with intracranial hypertension, since it decreases CBF and thus cerebral blood volume; however, it should be administered with caution in nonventilated patients with increased intracranial pressure, since its beneficial effects on cerebrovascular tone can be readily counteracted by the increase in arterial CO2 tension induced by this drug.

scholarly journals Cerebral Blood Flow During Plateau Waves in a Patient With Benign Intracranial Hypertension. Case Report.

2000 ◽  
Vol 40 (5) ◽  
pp. 287-292 ◽  
Author(s):  
Ryusuke KABEYA ◽  
Suguru INAO ◽  
Masanori TADOKORO ◽  
Masanari NISHINO ◽  
Jun YOSHIDA
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Case Report ◽  
Intracranial Hypertension ◽  
Benign Intracranial Hypertension ◽  
Plateau Waves

Benign intracranial hypertension: correlation of cerebral blood flow with disease severity

2001 ◽  
Vol 103 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Mordechai Lorberboym ◽  
Yair Lampl ◽  
Anat Kesler ◽  
Menahem Sadeh ◽  
Natan Gadot
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Hypertension ◽  
Disease Severity ◽  
Benign Intracranial Hypertension

scholarly journals Optic fenestration in benign intracranial hypertension: case report

2020 ◽  
Vol 6 (12) ◽  
pp. 2289
Author(s):  
Manish Munjal ◽  
Monika Singla ◽  
Sahil Goel ◽  
Porshia Rishi ◽  
Nitika Tuli ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Fluid Composition ◽  
Benign Intracranial Hypertension ◽  
Raised Intracranial Pressure ◽  
Visual Effects ◽  
Emergency Intervention ◽  
Diamond Burr

<p class="abstract"><span lang="EN-US">Condition of raised intracranial pressure without any mass lesion and normal cerebrospinal fluid composition is termed as idiopathic intracranial hypertension or pseudotumor cerebri. Raised intracranial tension with visual effects was treated by trans-sphenoidal optic fenestration as an emergency intervention to salvage the vision. The lamina papyracea on either side was lifted off the orbital periosteum and thick bone of the ethmoid sphenoidal junction was drilled with a diamond burr to thin it and elevate the bone covering the optic nerve.</span></p>

More than meets the eye: Papilledema from syphilis posing as idiopathic intracranial hypertension

2020 ◽  
Vol 31 (11) ◽  
pp. 1117-1119
Author(s):  
Sharon Chi ◽  
Amy Weintrob
Keyword(s):  
Cerebrospinal Fluid ◽  
Intracranial Pressure ◽  
Intracranial Hypertension ◽  
Idiopathic Intracranial Hypertension ◽  
Pseudotumor Cerebri ◽  
Elevated Intracranial Pressure ◽  
Fluid Production

Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, is a diagnosis of exclusion. Elevated intracranial pressure (ICP) can result from a variety of inflammatory and structural causes affecting cerebrospinal fluid production and absorption. First described in 1935, syphilis is a well-established cause of elevated ICP, referred to as syphilitic hydrocephalus. We report a case of a 49-year-old man presenting with vision changes and headache who was treated for IIH without resolution of symptoms, and eventually diagnosed with syphilitic hydrocephalus. Syphilis should be considered as a cause of elevated ICP prior to a diagnosis of IIH.

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