scholarly journals Postnatal growth of cardiomyocytes in the left ventricle of the rat

2004 ◽  
Vol 277A (1) ◽  
pp. 236-247 ◽  
Author(s):  
D. Wulfsohn ◽  
J.R. Nyengaard ◽  
Y. Tang
2014 ◽  
Vol 25 (6) ◽  
pp. 1214-1217 ◽  
Author(s):  
Sharon Borik ◽  
Christopher K. Macgowan ◽  
Mike Seed

AbstractUsing phase-contrast MRI in a foetus with borderline left ventricular hypoplasia at 37 weeks’ gestation we showed an increase in pulmonary blood flow during maternal hyperoxygenation. The associated increase in venous return to the left atrium, however, resulted in reversal of the atrial shunt, with no improvement in left ventricular output. The child initially underwent single ventricle palliation with a neonatal hybrid procedure, but following postnatal growth of the left ventricle tolerated conversion to a biventricular circulation at 5 months of age. We conclude that when there is significant restriction of filling or outflow obstruction across the left heart, neither prenatal nor postnatal acute pulmonary vasodilation can augment left ventricular output enough to support a biventricular circulation. Chronic pulmonary vasodilation may stimulate the growth of the left-sided structures allowing biventricular repair, raising the intriguing question of whether chronic maternal oxygen therapy might obviate the need for neonatal single ventricle pallation in the setting of borderline left ventricular hypoplasia.


2018 ◽  
Vol 17 (4) ◽  
pp. 110-121
Author(s):  
E. N. Pavlyukova ◽  
M. V. Kolosova ◽  
A. I. Unasheva ◽  
R. S. Karpov

The aimof the study is to assess the left ventricle (LV) untwist in healthy children and adolescents born fullterm.Materials and methods.The analysis was carried out in 108 healthy children aged 2 months to 18 years, born full-term. LV untwist is assessed using Speckle Tracking Imaging at the basal and apical level.Results.Four types of LV untwist were identified in children and adolescents. We did not find relation between LV untwist and age, nor with LV index spherical in systole and diastole, LV myocardial mass. The relationship between LV untwisting and LV rotation in systole at basal and apical segments was revealed.Conclusion.The described features of LV loosening are apparently associated with processes of postnatal growth and maturation of heart tissues in children and adolescents.


1999 ◽  
Vol 1 ◽  
pp. S101-S101
Author(s):  
O FOKINA ◽  
N TVERDOKHLEBOV ◽  
V SANDRIKOV ◽  
L KOUZNETZOVA

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