Turn-On Fluorogenic Probes for the Selective and Quantitative Detection of the Cyanide Anion from Natural Sources

A Co(ii) complex based on an AIE-active tetraarylethylene ligand displays selective fluorescence enhancement in the presence of cyanide anion in aqueous solution.

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A facile graphene oxide-based fluorescent nanosensor for the in situ “turn-on” detection of telomerase activity

The Analyst ◽

10.1039/c8an00402a ◽

2018 ◽

Vol 143 (10) ◽

pp. 2334-2341 ◽

Cited By ~ 10

Author(s):

Li Zhang ◽

Jie Peng ◽

Ming-Fang Hong ◽

Jia-Qing Chen ◽

Ru-Ping Liang ◽

...

Keyword(s):

Graphene Oxide ◽

Telomerase Activity ◽

Quantitative Detection ◽

Turn On

A graphene oxide-based fluorescent nanosensor has been proposed for the quantitative detection of telomerase and in situ imaging of intracellular telomerase.

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A Red Emissive Fluorescent Turn-on Sensor for the Rapid Detection of Selenocysteine and Its Application in Living Cells Imaging

Sensors ◽

10.3390/s20174768 ◽

2020 ◽

Vol 20 (17) ◽

pp. 4768 ◽

Cited By ~ 1

Author(s):

Zongcheng Wang ◽

Huihuang Zheng ◽

Chengliang Zhang ◽

Dongfang Tang ◽

Qiyao Wu ◽

...

Keyword(s):

Fluorescent Sensor ◽

High Sensitivity ◽

Living Cells ◽

Fluorescent Sensors ◽

Quantitative Detection ◽

Fast Reaction ◽

Detection Range ◽

Long Wavelength ◽

Turn On

The content of selenocysteine in cells has an important effect on a variety of human diseases, and the detection of selenocysteine by fluorescent sensors in vivo has shown many advantages. In order to further develop fast-reaction-time, good-selectivity, and high-sensitivity long-wavelength selenocysteine fluorescent sensors, we designed and synthesized the compound YZ-A4 as a turn-on fluorescent sensor to detect the content of selenocysteine. The quantitative detection range of the sensor YZ-A4 to selenocysteine was from 0 to 32 μM, and the detection limit was as low as 11.2 nM. The sensor displayed a rapid turn-on response, good selectivity, and high sensitivity to selenocysteine. Finally, we have demonstrated that YZ-A4 could be used for fluorescence imaging of selenocysteine in living cells.

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Dual enzyme-responsive “turn-on” fluorescence sensing systems based on in situ formation of 7-hydroxy-2-iminocoumarin scaffolds

Organic & Biomolecular Chemistry ◽

10.1039/c5ob01624j ◽

2015 ◽

Vol 13 (41) ◽

pp. 10348-10361 ◽

Cited By ~ 26

Author(s):

Sylvain Debieu ◽

Anthony Romieu

Keyword(s):

Domino Reactions ◽

Fluorescence Sensing ◽

Turn On ◽

Sensing Systems ◽

Fluorogenic Probes ◽

In Situ Formation

We herein report a novel class of dual enzyme-responsive fluorogenic probes based on two orthogonal deprotection reactions via the “covalent assembly” principle. Sensing of two different enzymes (hydrolase and nitroreductase) through domino reactions, producing the push–pull backbone of a fluorescent 3-substituted 7-hydroxy-2-iminocoumarin dye, is reported.

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A 2-Hydroxy-1-Naphthaldehyde Schiff Base for Turn-on Fluorescence Detection of Zn2+ based on PET Mechanism

10.21203/rs.3.rs-285879/v1 ◽

2021 ◽

Author(s):

Xinyue Mu ◽

Liping Shi ◽

Liqiang Yan ◽

Ningli Tang

Keyword(s):

Schiff Base ◽

Detection Limit ◽

Human Body ◽

Rapid Detection ◽

Zinc Ion ◽

Living Cells ◽

Quantitative Detection ◽

Real Samples ◽

Turn On ◽

Low Cytotoxicity

Abstract Zinc ion is closely related to human health. Its content in human body is small, while the effect is large. However, it is not the more the better, must be in a scientific balance. Therefore, it is significant to the rapid detection of Zn2+ in the environment and organism. Herein, a fluorescent probe based on 2-hydroxy-1-naphthalene formaldehyde and furan-2-carbohydrazide was conveniently synthesized via Schiff base reaction. And this probe has been successfully applied to the accurate and quantitative detection of Zn2+ in real samples, showing turn on fluorescence, good selectivity, very low detection limit, real time response and reusability. In addition, this probe has the potential application to trace Zn2+ in living cells with low cytotoxicity.

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