Methodology for real-time, multianalyte monitoring of fermentations using an in-situ mid-infrared sensor

2003 ◽  
Vol 82 (6) ◽  
pp. 702-709 ◽  
Author(s):  
Henri Kornmann ◽  
Martin Rhiel ◽  
Christopher Cannizzaro ◽  
Ian Marison ◽  
Urs von Stockar
Keyword(s):  
Real Time ◽  
Infrared Sensor ◽  
Mid Infrared

A method for real time detection of reaction endpoints using a moving window t-test of in situ time course data

2020 ◽  
Vol 5 (9) ◽  
pp. 1642-1646
Author(s):  
Elyse N. T. DiMaso ◽  
Robert W. Bondi ◽  
John Guo ◽  
Alexander G. O'Brien
Keyword(s):  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Real Time ◽  
Time Course ◽  
Test Method ◽  
Moving Window ◽  
Mid Infrared ◽  
Mid Infrared Spectroscopy ◽  
Time Course Data

In-line Fourier transform mid-infrared spectroscopy (FTIR) in combination with a moving window t-test method was used to determine the endpoint of a reaction with a highly inconsistent rate.

Hollow Waveguide-Enhanced Mid-Infrared Sensor for Real-Time Exhaled Methane Detection

2016 ◽  
Vol 28 (15) ◽  
pp. 1613-1616 ◽  
Author(s):  
Lin Liu ◽  
Bo Xiong ◽  
Yue Yan ◽  
Jinyi Li ◽  
Zhenhui Du
Keyword(s):  
Real Time ◽  
Infrared Sensor ◽  
Hollow Waveguide ◽  
Mid Infrared ◽  
Methane Detection

Evaluation of a newly developed mid-infrared sensor for real-time monitoring of yeast fermentations

2017 ◽  
Vol 123 (5) ◽  
pp. 651-657 ◽  
Author(s):  
Robert Schalk ◽  
Daniel Geoerg ◽  
Jens Staubach ◽  
Matthias Raedle ◽  
Frank-Juergen Methner ◽  
...  
Keyword(s):  
Real Time ◽  
Infrared Sensor ◽  
Real Time Monitoring ◽  
Mid Infrared

scholarly journals Towards Real-Time In-Situ Mid-Infrared Spectroscopic Ellipsometry in Polymer Processing

2021 ◽  
Author(s):  
Alexander Ebner ◽  
Robert Zimmerleiter ◽  
Kurt Hingerl ◽  
Markus Brandstetter
Keyword(s):  
Real Time ◽  
Spectroscopic Ellipsometry ◽  
Quantum Cascade Lasers ◽  
Polymer Processing ◽  
In Situ Monitoring ◽  
Acquisition Time ◽  
Angle Of Incidence ◽  
Mid Infrared ◽  
Ethylene Vinyl Alcohol

Recent developments in mid-infrared (MIR) spectroscopic ellipsometry enabled by quantum cascade lasers (QCLs) resulted in a drastic improvement in signal-to-noise ratio compared to conventional thermal emitter based instrumentation. Thus, it was possible to reduce the acquisition time for high-resolution broadband ellipsometric spectra from multiple hours to less than 1 second. This opens up new possibilities for real-time in-situ ellipsometry in polymer processing. To highlight these evolving capabilities we demonstrate the benefits of a QCL based MIR ellipsometer by investigating single and multilayered polymer films. The molecular structure and reorientation of a 2.5m thin biaxially oriented polyethylene terephtalate film is monitored during a stretching process lasting 24.5 s to illustrate the perspective of ellipsometric measurements in dynamic processes. In addition, a polyethylene/ethylene vinyl alcohol/polyethylene multilayer film is investigated at continuously varying angle of incidence ( 0∘ – 50∘) in 17.2 s, highlighting an unprecedented sample throughput for the technique of varying angle spectroscopic ellipsometry in the MIR spectral range. The obtained results underline the superior spectral and temporal resolution of QCL ellipsometry and qualify this technique as suitable method for advanced in-situ monitoring in polymer processing.

Real-time in situ monitoring of freely suspended and immobilized cell cultures based on mid-infrared spectroscopic measurements

2001 ◽  
Vol 77 (2) ◽  
pp. 174-185 ◽  
Author(s):  
Martin Rhiel ◽  
Paul Ducommun ◽  
Ivan Bolzonella ◽  
Ian Marison ◽  
Urs von Stockar
Keyword(s):  
Real Time ◽  
Cell Cultures ◽  
In Situ Monitoring ◽  
Immobilized Cell ◽  
Mid Infrared ◽  
Spectroscopic Measurements ◽  
Infrared Spectroscopic ◽  
Freely Suspended

scholarly journals Towards Real-Time In-Situ Mid-Infrared Spectroscopic Ellipsometry in Polymer Processing

Polymers ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 7
Author(s):  
Alexander Ebner ◽  
Robert Zimmerleiter ◽  
Kurt Hingerl ◽  
Markus Brandstetter
Keyword(s):  
Real Time ◽  
Spectroscopic Ellipsometry ◽  
Quantum Cascade Lasers ◽  
Polymer Processing ◽  
In Situ Monitoring ◽  
Acquisition Time ◽  
Angle Of Incidence ◽  
Mid Infrared ◽  
Ethylene Vinyl Alcohol

Recent developments in mid-infrared (MIR) spectroscopic ellipsometry enabled by quantum cascade lasers (QCLs) have resulted in a drastic improvement in signal-to-noise ratio compared to conventional thermal emitter based instrumentation. Thus, it was possible to reduce the acquisition time for high-resolution broadband ellipsometric spectra from multiple hours to less than 1 s. This opens up new possibilities for real-time in-situ ellipsometry in polymer processing. To highlight these evolving capabilities, we demonstrate the benefits of a QCL based MIR ellipsometer by investigating single and multilayered polymer films. The molecular structure and reorientation of a 2.5 µm thin biaxially oriented polyethylene terephthalate film is monitored during a stretching process lasting 24.5 s to illustrate the perspective of ellipsometric measurements in dynamic processes. In addition, a polyethylene/ethylene vinyl alcohol/polyethylene multilayer film is investigated at a continuously varying angle of incidence (0∘– 50∘) in 17.2 s, highlighting an unprecedented sample throughput for the technique of varying angle spectroscopic ellipsometry in the MIR spectral range. The obtained results underline the superior spectral and temporal resolution of QCL ellipsometry and qualify this technique as a suitable method for advanced in-situ monitoring in polymer processing.

scholarly journals Real-Time In Situ Secondary Structure Analysis of Protein Monolayer with Mid-Infrared Plasmonic Nanoantennas

ACS Sensors ◽  
2018 ◽  
Vol 3 (6) ◽  
pp. 1109-1117 ◽  
Author(s):  
Dordaneh Etezadi ◽  
John B. Warner ◽  
Hilal A. Lashuel ◽  
Hatice Altug
Keyword(s):  
Secondary Structure ◽  
Real Time ◽  
Structure Analysis ◽  
Mid Infrared ◽  
Secondary Structure Analysis ◽  
Plasmonic Nanoantennas ◽  
Protein Monolayer

Real-time analyte monitoring of a fungal fermentation, at pilot scale, using in situ mid-infrared spectroscopy

2001 ◽  
Vol 24 (1) ◽  
pp. 13-24 ◽  
Author(s):  
Pollard D. ◽  
Buccino R. ◽  
Connors N. ◽  
Kirschner T. ◽  
Olewinski R. ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Real Time ◽  
Pilot Scale ◽  
Mid Infrared ◽  
Mid Infrared Spectroscopy ◽  
Fungal Fermentation
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