An LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma

2016 ◽  
Vol 31 (2) ◽  
pp. e3793 ◽  
Author(s):  
Ali S. Abdelhameed ◽  
Mohamed W. Attwa ◽  
Adnan A. Kadi
Keyword(s):  
Protein Kinase ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
High Throughput ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors

A robust and quantitative assay platform for multiplexed, high throughput screening of protein kinase inhibitors

2016 ◽  
Vol 52 (81) ◽  
pp. 12112-12115 ◽  
Author(s):  
Jieon Lee ◽  
Il-Soo Park ◽  
Ginam Park ◽  
Kyukwang Cho ◽  
Hee-Sung Park ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Protein Kinase ◽  
High Throughput ◽  
High Throughput Screening ◽  
Kinase Activity ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
Protein Kinase Activity ◽  
Activity Assay ◽  
Kinase Activity Assay

We present a new platform for multiplexed protein kinase activity assay using TiO2decorated graphene oxide (GO), which is applicable to high throughput inhibitor screening.

Development and clinical application of a LC-MS/MS method for simultaneous determination of various tyrosine kinase inhibitors in human plasma

2012 ◽  
Vol 413 (1-2) ◽  
pp. 143-149 ◽  
Author(s):  
Lutz Götze ◽  
Axel Hegele ◽  
Stephan Klaus Metzelder ◽  
Harald Renz ◽  
Wolfgang Andreas Nockher
Keyword(s):  
Tyrosine Kinase ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Tyrosine Kinase Inhibitors ◽  
Clinical Application ◽  
Kinase Inhibitors

High throughput LC–MS/MS method for simultaneous determination of zidovudine, lamivudine and nevirapine in human plasma

2013 ◽  
Vol 921-922 ◽  
pp. 9-14 ◽  
Author(s):  
Valluru Rajani Kumar ◽  
B. Phani Bhushana Reddy ◽  
B. Ravi Kumar ◽  
K. Sreekanth ◽  
Kilaru Naveen Babu
Keyword(s):  
Simultaneous Determination ◽  
Human Plasma ◽  
High Throughput

Development and validation of a sensitive and high-throughput LC-MS/MS method for the simultaneous determination of esomeprazole and naproxen in human plasma

2013 ◽  
Vol 27 (7) ◽  
pp. 894-899 ◽  
Author(s):  
Shanmugam Gopinath ◽  
Ramadass Satiesh Kumar ◽  
Madhira bhawani Shankar ◽  
Palanisamy Danabal
Keyword(s):  
Simultaneous Determination ◽  
Human Plasma ◽  
High Throughput ◽  
Development And Validation

Fluorescent biosensors for high throughput screening of protein kinase inhibitors

2013 ◽  
Vol 9 (2) ◽  
pp. 253-265 ◽  
Author(s):  
Camille Prével ◽  
Morgan Pellerano ◽  
Thi Nhu Ngoc Van ◽  
May C. Morris
Keyword(s):  
Protein Kinase ◽  
High Throughput ◽  
High Throughput Screening ◽  
Kinase Inhibitors ◽  
Protein Kinase Inhibitors ◽  
Fluorescent Biosensors
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