Combining network pharmacology with chromatographic fingerprinting and multi‐component quantitative analysis for the quality evaluation of Astragali Radix

2022 ◽  
Author(s):  
Xiaohuan Li ◽  
Xinhua Guo ◽  
Miao Sha ◽  
Wenyuan Gao ◽  
Xia Li
Keyword(s):  
Quantitative Analysis ◽  
Quality Evaluation ◽  
Network Pharmacology ◽  
Astragali Radix ◽  
Chromatographic Fingerprinting

scholarly journals Chromatographic fingerprinting and quantitative analysis for the quality evaluation of Xinkeshu tablet

2012 ◽  
Vol 2 (6) ◽  
pp. 422-430 ◽  
Author(s):  
Pei Wang ◽  
Lian Li ◽  
Hailong Yang ◽  
Shijuan Cheng ◽  
Yingzi Zeng ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Quality Evaluation ◽  
Chromatographic Fingerprinting

Quality Evaluation of Astragali Radix Products by Quantitative Analysis of Multi-components by Single Marker

2013 ◽  
Vol 5 (4) ◽  
pp. 272-279 ◽  
Author(s):  
Jie SUN ◽  
Zhen-zuo JIANG ◽  
Rui-qing YAN ◽  
Olajide OLALEYE ◽  
Xiao-long ZHANG ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Quality Evaluation ◽  
Astragali Radix ◽  
Single Marker

scholarly journals Quality Evaluation of Fritillaria thunbergii by High-Performance Liquid Chromatography Fingerprinting Coupled with Multicomponent Quantitative Analysis

2021 ◽  
Vol 25 (01) ◽  
pp. 131-138
Author(s):  
Ruoxu He
Keyword(s):  
Quantitative Analysis ◽  
High Performance ◽  
Quality Evaluation ◽  
Light Scattering Detection ◽  
Mobile Phases ◽  
Evaporative Light Scattering ◽  
Significant Difference ◽  
The Family ◽  
Main Production ◽  
Main Components

Medicinal Zhebeimu refers to the dried bulb of the plant Fritillaria thunbergii, which belongs to the family Liliaceae. Their main production sites are in Zhejiang, Jiangsu, and Anhui Provinces, with alkaloids as the main components. In this study, according to Chinese Pharmacopoeia, different mobile phases were investigated. Because most alkaloids in Fritillaria do not have UV absorption, evaporative light scattering detection (ELSD) was used instead of UV to produce the HPLC-ELSD spectra for five F. thunbergii samples and other samples, e.g. F. chuanxiensis, F. anhuiensis, and F. ussuriensis. Comparison showed significant differences exist among these species. There was no significant difference between the F. thunbergii samples produced in Zhejiang, which clustered together in both the cluster analyses. However, the F. thunbergii samples produced in Nantong, Jiangsu and the F. thunbergii samples produced in Zhejiang were separated in the clustering chart, which may be caused by different cultivation environments. The obtained results showed that the combination of quantitative analysis and chromatographic fingerprint analysis can be readily utilized for quality control purposes, offering a comprehensive strategy for quality evaluation of F. thunbergii and related products. © 2021 Friends Science Publishers

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