scholarly journals Hybrid liposomes inhibit tumor growth and lung metastasis of murine osteosarcoma cells

2013 ◽  
Vol 2 (3) ◽  
pp. 267-276 ◽  
Author(s):  
Hideki Kitajima ◽  
Yuji Komizu ◽  
Hideaki Ichihara ◽  
Koichi Goto ◽  
Ryuichi Ueoka
Keyword(s):  
Tumor Growth ◽  
Lung Metastasis ◽  
Osteosarcoma Cells ◽  
Inhibit Tumor Growth ◽  
Murine Osteosarcoma

scholarly journals Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo

2007 ◽  
Author(s):  
Taka-aki Matsui ◽  
Hiroaki Murata ◽  
Tomoya Sakabe ◽  
Yoshihiro Sowa ◽  
Naoyuki Horie ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Tumor Growth ◽  
Cell Cycle Arrest ◽  
Osteosarcoma Cells ◽  
Cycle Arrest ◽  
Murine Osteosarcoma

scholarly journals RGD Peptide and PAD4 Inhibitor-Loaded Gold Nanorods for Chemo-Photothermal Combined Therapy to Inhibit Tumor Growth, Prevent Lung Metastasis and Improve Biosafety

2021 ◽  
Vol Volume 16 ◽  
pp. 5565-5580
Author(s):  
Yu Lu ◽  
Zidong Peng ◽  
Di Zhu ◽  
Yijiang Jia ◽  
Ayijiang Taledaohan ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Lung Metastasis ◽  
Gold Nanorods ◽  
Combined Therapy ◽  
Rgd Peptide ◽  
Inhibit Tumor Growth

scholarly journals A Dual-Targeting Ruthenium Nanodrug that Inhibits Primary Tumor Growth and Lung Metastasis by the PARP/ATM Pathway

2020 ◽  
Author(s):  
Yu Lu ◽  
Di Zhu ◽  
Lin Gui ◽  
Yuanming Li ◽  
Wenjing Wang ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Lung Metastasis ◽  
Dna Cleavage ◽  
Tumor Tissue ◽  
Chloride Ions ◽  
Inhibit Tumor Growth ◽  
Dual Targeting ◽  
Cd31 Expression

Abstract Many studies have found that ruthenium complexes have unique biochemical characteristics and thus inhibit tumor growth or metastasis. Our aim was to report a novel dual-targeting ruthenium candidate 2b with both antitumor and antimetastatic functions that could target tumor sites using both EPR effects and TF/TFR. It was composed of ruthenium-complexed carboline acid and four chloride ions. In vitro, 2b could trigger DNA cleavage and thus block the cell cycle and cause apoptosis by the PARP/ATM pathway. In vivo, 2b could inhibit not only LLC tumor growth but also lung metastasis. We found apoptosis and decrease in CD31 expression in tumor tissue. In addition, we also found that 2b could collect in tumor tissue. Thus, we concluded that 2b could target tumors, inhibit tumor growth and prevent lung metastasis.

Nerve Growth Factor overexpression in Clara cells suppresses metastasis and tumor growth in a mouse model of experimental lung metastasis

Pneumologie ◽  
2012 ◽  
Vol 66 (06) ◽  
Author(s):  
K Seidler ◽  
A Sydykov ◽  
S Müller-Brüsselbach ◽  
R Müller ◽  
N Weißmann ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Mouse Model ◽  
Tumor Growth ◽  
Lung Metastasis ◽  
Clara Cells ◽  
Nerve Growth

Indirubin-3′-Oxime (IDR3O) Inhibits Proliferation of Osteosarcoma Cells in vitro and Tumor Growth in vivo Through AMPK-Activation and PGC-1α/TFAM Up-Regulation

2020 ◽  
Vol 495 (1) ◽  
pp. 354-360
Author(s):  
Bing Fu ◽  
Guorui Yin ◽  
Ke Song ◽  
Xiurui Mu ◽  
Bo Xu ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Ampk Activation ◽  
Osteosarcoma Cells

Mutations That Increase the Life Span of C. elegans Inhibit Tumor Growth

Science ◽  
2006 ◽  
Vol 313 (5789) ◽  
pp. 971-975 ◽  
Author(s):  
J. M. Pinkston
Keyword(s):  
Tumor Growth ◽  
Life Span ◽  
Inhibit Tumor Growth ◽  
C Elegans

scholarly journals G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

2020 ◽  
Vol 180 (3) ◽  
pp. 635-646 ◽  
Author(s):  
Kaitlyn J. Andreano ◽  
Suzanne E. Wardell ◽  
Jennifer G. Baker ◽  
Taylor K. Desautels ◽  
Robert Baldi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Animal Models ◽  
Tumor Growth ◽  
Inhibit Tumor Growth
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