scholarly journals Erratum: Singh A, Rokes C, Gireud M, et al. Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCFβ-TRCP in neuroblastoma cells. Cancer. 2011;117:5189-5202.

Cancer ◽  
2018 ◽  
Vol 124 (11) ◽  
pp. 2458-2458
2012 ◽  
Vol 151 (6) ◽  
pp. 611-620 ◽  
Author(s):  
Kouji Tanaka ◽  
Keiko Tamiya-Koizumi ◽  
Kazumi Hagiwara ◽  
Hiromi Ito ◽  
Akira Takagi ◽  
...  

2009 ◽  
Vol 21 (6) ◽  
pp. 881-891 ◽  
Author(s):  
Pei-Yu Wu ◽  
Yu-Chia Lin ◽  
Chia-Ling Chang ◽  
Hsing-Tsen Lu ◽  
Chia-Hsuan Chin ◽  
...  

2005 ◽  
Vol 388 (3) ◽  
pp. 941-948 ◽  
Author(s):  
Anna M. BROWN ◽  
Fiona C. RIDDOCH ◽  
Andrew ROBSON ◽  
Christopher P. F. REDFERN ◽  
Timothy R. CHEEK

We have investigated effects of neuronal differentiation on hormone-induced Ca2+ entry. Fura-2 fluorescence measurements of undifferentiated SH-SY5Y neuroblastoma cells, stimulated with methacholine, revealed the presence of voltage-operated Ca2+-permeable, Mn2+-impermeable entry pathways, and at least two voltage-independent Ca2+- and Mn2+-permeable entry pathways, all of which apparently contribute to both peak and plateau phases of the Ca2+ signal. Similar experiments using 9-cis retinoic acid-differentiated cells, however, revealed voltage-operated Ca2+-permeable, Mn2+-impermeable channels, and, more significantly, the absence or down-regulation of the most predominant of the voltage-independent entry pathways. This down-regulated pathway is probably due to CCE (capacitative Ca2+ entry), since thapsigargin also stimulated Ca2+ and Mn2+ entry in undifferentiated but not differentiated cells. The Ca2+ entry components remaining in methacholine-stimulated differentiated cells contributed to only the plateau phase of the Ca2+ signal. We conclude that differentiation of SH-SY5Y cells results in a mechanistic and functional change in hormone-stimulated Ca2+ entry. In undifferentiated cells, voltage-operated Ca2+ channels, CCE and NCCE (non-CCE) pathways are present. Of the voltage-independent pathways, the predominant one appears to be CCE. These pathways contribute to both peak and plateau phases of the Ca2+ signal. In differentiated cells, CCE is either absent or down-regulated, whereas voltage-operated entry and NCCE remain active and contribute to only the plateau phase of the Ca2+ signal.


Cancer ◽  
2011 ◽  
Vol 117 (22) ◽  
pp. 5189-5202 ◽  
Author(s):  
Akanksha Singh ◽  
Christopher Rokes ◽  
Monica Gireud ◽  
Stephen Fletcher ◽  
James Baumgartner ◽  
...  

2013 ◽  
Vol 225 (03) ◽  
Author(s):  
F Sherkheli ◽  
S Ackermann ◽  
F Roels ◽  
H Kocak ◽  
R Volland ◽  
...  

2008 ◽  
Vol 16 (17) ◽  
pp. 8301-8313 ◽  
Author(s):  
Mohamed Sayed Gomaa ◽  
Jane L. Armstrong ◽  
Beatrice Bobillon ◽  
Gareth J. Veal ◽  
Andrea Brancale ◽  
...  

1988 ◽  
Vol 8 (4) ◽  
pp. 1677-1683 ◽  
Author(s):  
C J Thiele ◽  
P S Cohen ◽  
M A Israel

We detected expression of the c-myb proto-oncogene, which was initially thought to be expressed in a tissue-specific manner in cells of hematopoietic lineage, in human tissues of neuronal origin. Since the level of c-myb expression declined during fetal development, we studied the regulation of its expression in human neuroblastoma cell lines induced to differentiate by retinoic acid. The expression of c-myb declined during the maturation of neuroblastoma cells, and this change was mediated by a decrease in c-myb transcription.


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