Tumor-Targeting Anti-MicroRNA-155 Delivery Based on Biodegradable Poly(ester amine) and Hyaluronic Acid Shielding for Lung Cancer Therapy

ChemPhysChem ◽  
2018 ◽  
Vol 19 (16) ◽  
pp. 2058-2069 ◽  
Author(s):  
Yi Yang ◽  
Yanpeng Jia ◽  
Yao Xiao ◽  
Ying Hao ◽  
Lan Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Hyaluronic Acid ◽  
Cancer Therapy ◽  
Tumor Targeting ◽  
Biodegradable Poly ◽  
Lung Cancer Therapy

Hyaluronic acid-modified zirconium phosphate nanoparticles for potential lung cancer therapy

2017 ◽  
Vol 62 (1) ◽  
Author(s):  
Ranwei Li ◽  
Tiecheng Liu ◽  
Ke Wang
Keyword(s):  
Lung Cancer ◽  
Hyaluronic Acid ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Tumor Targeting ◽  
Zirconium Phosphate ◽  
Drug Loading ◽  
Lung Cancer Therapy ◽  
Targeting Ability ◽  
A549 Lung

AbstractNovel tumor-targeting zirconium phosphate (ZP) nanoparticles modified with hyaluronic acid (HA) were developed (HA-ZP), with the aim of combining the drug-loading property of ZP and the tumor-targeting ability of HA to construct a tumor-targeting paclitaxel (PTX) delivery system for potential lung cancer therapy. The experimental results indicated that PTX loading into the HA-ZP nanoparticles was as high as 20.36%±4.37%, which is favorable for cancer therapy. PTX-loaded HA-ZP nanoparticles increased the accumulation of PTX in A549 lung cancer cells via HA-mediated endocytosis and exhibited superior anticancer activity

Esterase-sensitive cleavable histone deacetylase inhibitor-coupled hyaluronic acid nanoparticles for boosting anticancer activities against lung adenocarcinoma

2019 ◽  
Vol 7 (11) ◽  
pp. 4624-4635 ◽  
Author(s):  
Song Yi Lee ◽  
Eun-Hye Hong ◽  
Jae Young Jeong ◽  
Jaewon Cho ◽  
Ji-Hye Seo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Hyaluronic Acid ◽  
Cancer Therapy ◽  
Lung Adenocarcinoma ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Anticancer Activities ◽  
Deacetylase Inhibitor ◽  
Lung Cancer Therapy ◽  
Phenylbutyric Acid

4-Phenylbutyric acid (PBA)-installed hyaluronic acid (HA)-based nanoparticles (NPs) were developed for amplifying the anticancer potential of curcumin (CUR) for lung cancer therapy.

Enhancement of gold-nanocluster-mediated chemotherapeutic efficiency of cisplatin in lung cancer

2021 ◽  
Author(s):  
Mei Jiang ◽  
Yuchen Lin ◽  
Xiaocui Fang ◽  
Mingpeng Liu ◽  
Lilusi Ma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Delivery System ◽  
Gold Nanoclusters ◽  
Cationic Peptide ◽  
Gold Nanocluster ◽  
Lung Cancer Therapy ◽  
Anti Tumor Activity

A novel delivery system for cisplatin based on electrostatics-mediated assemblies of gold nanoclusters and PEGylated cationic peptide was constructed. The constructed cisplatin@GC-pKs showed much enhanced anti-tumor activity for lung cancer therapy.

Nanomedicine as an emerging platform for metastatic lung cancer therapy

2015 ◽  
Vol 34 (2) ◽  
pp. 291-301 ◽  
Author(s):  
Dalit Landesman-Milo ◽  
Srinivas Ramishetti ◽  
Dan Peer
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung ◽  
Lung Cancer Therapy
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