scholarly journals Plate Design for and Cherry Picking of Bacterial RNAi Clones for Systematic Error Detection in High-Throughput Caenorhabditis elegans RNAi Screens

2018 ◽  
Vol 124 (1) ◽  
pp. e70
Author(s):  
Sakthimala Jagadeesan ◽  
Abdul Hakkim
Keyword(s):  
Caenorhabditis Elegans ◽  
Systematic Error ◽  
High Throughput ◽  
Error Detection ◽  
Plate Design ◽  
Cherry Picking

scholarly journals Systematic error detection in experimental high-throughput screening

2011 ◽  
Vol 12 (1) ◽  
pp. 25 ◽  
Author(s):  
Plamen Dragiev ◽  
Robert Nadon ◽  
Vladimir Makarenkov
Keyword(s):  
Systematic Error ◽  
High Throughput ◽  
Error Detection ◽  
High Throughput Screening

Systematic error detection for RFID reliability

2006 ◽  
Author(s):  
S. Inoue ◽  
D. Hagiwara ◽  
H. Yasuura
Keyword(s):  
Systematic Error ◽  
Error Detection

High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins

2003 ◽  
Vol 307 (4) ◽  
pp. 928-934 ◽  
Author(s):  
Raymond Y Huang ◽  
Simon J Boulton ◽  
Marc Vidal ◽  
Steve C Almo ◽  
Anne R Bresnick ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
High Throughput ◽  
Purification And Characterization

scholarly journals High-Throughput Profiling of Caenorhabditis elegans Starvation-Responsive microRNAs

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142262 ◽  
Author(s):  
Laura Garcia-Segura ◽  
Cei Abreu-Goodger ◽  
Armando Hernandez-Mendoza ◽  
Tzvetanka D. Dimitrova Dinkova ◽  
Luis Padilla-Noriega ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
High Throughput

A novel high-throughput nematicidal assay using embryo cells and larvae of Caenorhabditis elegans

2014 ◽  
Vol 139 ◽  
pp. 33-41 ◽  
Author(s):  
Yiling Lai ◽  
Meichun Xiang ◽  
Shuchun Liu ◽  
Erwei Li ◽  
Yongsheng Che ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
High Throughput ◽  
Embryo Cells

scholarly journals CAENORHABDITIS ELEGANS AS A MODEL OF AIR POLLUTION TOXICITY DURING DEVELOPMENT AND LIFESPAN

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S97-S97
Author(s):  
Amin Haghani ◽  
Hans M Dalton ◽  
Nikoo Safi ◽  
Farimah Shirmohammadi ◽  
Constantinos Sioutas ◽  
...  
Keyword(s):  
Air Pollution ◽  
Caenorhabditis Elegans ◽  
Mouse Models ◽  
High Throughput ◽  
Molecular Mechanisms ◽  
Cultured Cells ◽  
Exposure Model ◽  
C Elegans ◽  
Biological Responses ◽  
Short Term Exposure

Abstract Air pollution (AirPoll) is among the leading human mortality risk factors and yet little is known about the molecular mechanisms of this global environmental toxin. Our recent studies using mouse models even showed genetic variation and sex can alter biological responses to air pollution. To expand genetic studies of AirPoll toxicity throughout the lifespan, we introduced Caenorhabditis elegans as a new AirPoll exposure model which has a short lifespan, high throughput capabilities and shared longevity pathways with mammals. Acute exposure of C. elegans to airborne nanosized AirPoll matter (nPM) caused similar gene expression changes to our prior findings in cell culture and mouse models. Initial C. elegans responses to nPM included antioxidant, inflammatory and Alzheimer homolog genes. The magnitude of changes was dependent on the developmental stage of the worms. Even short term exposure of C. elegans to nPM altered developmental and lifespan hormetic effects, with pathways that included skn-1/Nrf family antioxidant responses. We propose C. elegans as a new and complementary model for mouse and cultured cells to study AirPoll across the lifespan. Future chronic nPM exposure and high throughput genetic screening of C. elegans can identify other major regulators of the developmental and lifespan effects of air pollution. This work was supported by grants R01AG051521 (CEF); R21AG05020 (CEF); Cure Alzheimer’s Fund (CEF); R01GM109028 (SPC), F31AG051382 (HMD) and T32AG000037 (HMD), T32AG052374 (AH).

A Tool for the Design and Evaluation of Alternative Quality-Control Procedures

1992 ◽  
Vol 38 (2) ◽  
pp. 204-210 ◽  
Author(s):  
Aristides T Hatjimihail
Keyword(s):  
Quality Control ◽  
Systematic Error ◽  
Power Function ◽  
Error Detection ◽  
Simulation Program ◽  
Analytical Process ◽  
Defect Rate ◽  
Control Procedures ◽  
Definition Of ◽  
Design Comparison

Abstract I have developed an interactive microcomputer simulation program for the design, comparison, and evaluation of alternative quality-control (QC) procedures. The program estimates the probabilities for rejection under different conditions of random and systematic error when these procedures are used and plots their power function graphs. It also estimates the probabilities for detection of critical errors, the defect rate, and the test yield. To allow a flexible definition of the QC procedures, it includes an interpreter. Various characteristics of the analytical process and the QC procedure can be user-defined. The program extends the concepts of the probability for error detection and of the power function to describe the results of the introduction of error between runs and within a run. The usefulness of this approach is illustrated with some examples.

scholarly journals A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay

2010 ◽  
Vol 245 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Windy A. Boyd ◽  
Sandra J. McBride ◽  
Julie R. Rice ◽  
Daniel W. Snyder ◽  
Jonathan H. Freedman
Keyword(s):  
Caenorhabditis Elegans ◽  
High Throughput ◽  
Chemical Toxicity ◽  
High Throughput Method
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