The role of selective transport in neuronal polarization

2011 ◽  
Vol 71 (6) ◽  
pp. 445-457 ◽  
Author(s):  
Takashi Namba ◽  
Shinichi Nakamuta ◽  
Yasuhiro Funahashi ◽  
Kozo Kaibuchi
2010 ◽  
Vol 14 (05) ◽  
pp. 389-396
Author(s):  
Carl A. Barker ◽  
Alan Massey ◽  
Aidan Rhodes ◽  
Martin R. Bryce ◽  
Ritu Kataky

Judiciously designed phthalocyanines (Pcs), such as silicon-Pc bis(3,5-diphenyl)benzoate (1c), with axial substituents which prevent aggregation, can self-assemble to form ordered nanoporous films on electrode surfaces. In this paper, complementary techniques such as Scanning Kelvin Nanoprobe (SKN) microscopy, Atom Force Microscopy (AFM) and electrochemical measurements are used to demonstrate that films formed by silicon-Pc bis(3,5-diphenyl)benzoate allow size- and charge- selective transport of probe molecules through well-defined intermolecular cavities. In contrast, the analogs silicon-Pc bis(4-tert-butylbenzoate) (1a) and silicon-Pc bis(3-thienyl)acetate (1b) have different film morphologies when solvent-cast in the same manner and block the electrode surface. The role of the different axial substituents in orienting the molecules on the substrate is discussed.


2008 ◽  
Vol 319 (2) ◽  
pp. 502
Author(s):  
Shailesh K. Gupta ◽  
Rashmi Mishra ◽  
David Juncker ◽  
Karina F. Meiri ◽  
Shyamala Mani

2022 ◽  
Vol 1 (6) ◽  
pp. 149-162
Author(s):  
Rara Inggarsih ◽  
Ella Amalia ◽  
Septi Purnamasari

The cell membrane plays an important role in cell traffic because it functions to secrete various molecules. The selective transport system allows the movement of molecules into or out of the cell compartment. By controlling the movement of substances from one compartment to another, membranes exert a strong influence on metabolic pathways. Cell membranes are composed of proteins and lipids with a very important function in maintaining the rhythm of circulation and cell transport. In addition, the cell membrane also plays a role in maintaining the integrity and relationship, and communication of cells.


Author(s):  
Nariko Arimura ◽  
Takeshi oshimura ◽  
Kozo Kaibuchi

1971 ◽  
Vol 54 (12) ◽  
pp. 1886-1894 ◽  
Author(s):  
K.L. Smith ◽  
L.A. Muir ◽  
L.C. Ferguson ◽  
H.R. Conrad

2020 ◽  
Author(s):  
Manu Goyal ◽  
Xiyan Zhao ◽  
Mariya Bozhinova ◽  
Karla Lisette Andrade López ◽  
Cecilia de Heus ◽  
...  

ABSTRACTCoat protein complex I (COPI)-coated vesicles mediate membrane trafficking between Golgi cisternae as well as retrieval of proteins from the Golgi to the endoplasmic reticulum. There are several flavors of the COPI coat defined by paralogous subunits of the protein complex coatomer. However, whether paralogous COPI proteins have specific functions is currently unknown. Here we show that the paralogous coatomer subunits γ1-COP and γ2-COP are differentially expressed during the neuronal differentiation of mouse pluripotent cells. Moreover, through a combination of genome editing experiments, we demonstrate that whereas γ-COP paralogs are largely functionally redundant, γ1-COP specifically promotes neurite outgrowth. Our work stresses a role of the COPI pathway in neuronal polarization and provides evidence for distinct functions for coatomer paralogous subunits in this process.


2019 ◽  
Vol 223 (2) ◽  
pp. 514-516 ◽  
Author(s):  
Devrim Coskun ◽  
Rupesh Deshmukh ◽  
Humira Sonah ◽  
James G. Menzies ◽  
Olivia Reynolds ◽  
...  
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