scholarly journals A structure‐activity investigation on modified analogues of an argininocalixarene based non‐viral gene vector

2021 ◽  
Author(s):  
Michela Lomazzi ◽  
Valentina Franceschi ◽  
Valentina Bagnacani ◽  
Carlo Alberto Vezzoni ◽  
Gaetano Donofrio ◽  
...  
Keyword(s):  
Viral Gene ◽  
Gene Vector ◽  
Structure Activity

Structure–activity relationship studies of symmetrical cationic bolasomes as non-viral gene vectors

2016 ◽  
Vol 4 (33) ◽  
pp. 5575-5584 ◽  
Author(s):  
Zheng Huang ◽  
Yi-Mei Zhang ◽  
Qian Cheng ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Viral Gene ◽  
Structure Activity ◽  
Gene Delivery Vectors ◽  
Gene Vectors

Bolalipids based on lysine or cyclen headgroups were synthesized and their structure–activity relationship as gene delivery vectors was studied.

scholarly journals Cationic lipids with a cyclen headgroup: synthesis and structure–activity relationship studies as non-viral gene vectors

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18681-18689 ◽  
Author(s):  
De-Chun Chang ◽  
Yi-Mei Zhang ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
Xiao-Qi Yu
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Cationic Lipids ◽  
Activity Relationship ◽  
Viral Gene ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Gene Delivery Vectors ◽  
Gene Vectors ◽  
Viral Gene Delivery

The structure–activity relationships of cyclen-based cationic lipids as non-viral gene delivery vectors were studied and clarified.

Novel Organic-Inorganic Hybrid Nanoparticles as Non-Viral Gene Vector

2008 ◽  
Vol 47-50 ◽  
pp. 1319-1322
Author(s):  
Yang Zhao ◽  
Pei Yin ◽  
Zu Yong Wang ◽  
Lei Ren ◽  
Qi Qing Zhang
Keyword(s):  
Gene Therapy ◽  
Encapsulation Efficiency ◽  
Sol Gel ◽  
Hybrid Nanoparticles ◽  
Viral Gene ◽  
Gene Vector ◽  
Inorganic Hybrid ◽  
Sol Gel Process ◽  
Gene Vectors

Novel hybrid biomaterial of gelatin-siloxane nanoparticles (GS NPs), with positive surface potential and lower cytotoxicity, was synthesized through a 2-step sol-gel process. The pDNA-GS NPs complex was formulated with high encapsulation efficiency, and exhibited and efficient transfection in vitro. We thus envision that the GS NPs material could serve as non-viral gene vectors for gene therapy.

A naphthalimide-based [12]aneN3 compound as an effective and real-time fluorescence tracking non-viral gene vector

2015 ◽  
Vol 51 (93) ◽  
pp. 16695-16698 ◽  
Author(s):  
Yong-Guang Gao ◽  
You-Di Shi ◽  
Ying Zhang ◽  
Jing Hu ◽  
Zhong-Lin Lu ◽  
...  
Keyword(s):  
Real Time ◽  
Organic Molecule ◽  
Gene Transfection ◽  
Viral Gene ◽  
Gene Vector ◽  
Macrocyclic Polyamine ◽  
Small Organic Molecule

A small organic molecule containing naphthalimide and macrocyclic polyamine 12[ane]N3 moieties showed effective and fluorescence tracking gene transfection properties.

Effects of heterocyclic-based head group modifications on the structure–activity relationship of tocopherol-based lipids for non-viral gene delivery

2016 ◽  
Vol 14 (28) ◽  
pp. 6857-6870 ◽  
Author(s):  
Mallikarjun Gosangi ◽  
Thasneem Yoosuf Mujahid ◽  
Vijaya Gopal ◽  
Srilakshmi V. Patri
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Nucleic Acids ◽  
Viral Gene ◽  
Head Group ◽  
P Gene ◽  
Promising Strategy ◽  
Structure Activity ◽  
Viral Gene Delivery ◽  
Relationship Of

Gene therapy, a promising strategy for the delivery of therapeutic nucleic acids, is greatly dependent on the development of efficient vectors.

A luminescent tetranuclear ruthenium(ii) complex as a tracking non-viral gene vector

2013 ◽  
Vol 49 (8) ◽  
pp. 810-812 ◽  
Author(s):  
Bole Yu ◽  
Yu Chen ◽  
Cheng Ouyang ◽  
Huaiyi Huang ◽  
Liangnian Ji ◽  
...  
Keyword(s):  
Viral Gene ◽  
Gene Vector

A novel non-viral gene vector for hepatocyte-targeting and in situ monitoring of DNA delivery in single cells

RSC Advances ◽  
2016 ◽  
Vol 6 (55) ◽  
pp. 50053-50060 ◽  
Author(s):  
Yong-Guang Gao ◽  
Quan Tang ◽  
You-Di Shi ◽  
Ying Zhang ◽  
Ruibing Wang ◽  
...  
Keyword(s):  
Single Cells ◽  
Dna Delivery ◽  
In Situ Monitoring ◽  
Viral Gene ◽  
Gene Vector
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