Selection bias correction for species sensitivity distribution modeling and hazardous concentration estimation

2015 ◽  
Vol 34 (11) ◽  
pp. 2555-2563 ◽  
Author(s):  
David R. Fox
Keyword(s):  
Selection Bias ◽  
Bias Correction ◽  
Species Sensitivity Distribution ◽  
Species Sensitivity ◽  
Distribution Modeling ◽  
Sensitivity Distribution ◽  
Concentration Estimation ◽  
Hazardous Concentration

scholarly journals Comparative Aquatic Toxicity of Gold Nanoparticles and Ionic Gold Using a Species Sensitivity Distribution Approach

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Tarryn L. Botha ◽  
Tanyn E. James ◽  
Victor Wepener
Keyword(s):  
Gold Nanoparticles ◽  
Aquatic Toxicity ◽  
Single Species ◽  
Species Sensitivity Distribution ◽  
Toxicity Tests ◽  
Species Sensitivity ◽  
Sensitivity Distribution ◽  
Hazardous Concentration ◽  
Toxic Potential ◽  
Ionic Gold

Gold nanoparticles (nAu) are used in drug delivery systems allowing for targeted cellular distribution. The effects of increased use and release of nanoparticles into the environment are not well known. A species sensitivity distribution (SSD) allows for the ecotoxicological hazard assessment of a chemical based on single species toxicity tests. Aquatic toxicity needs to be related to particle characterization in order to understand the effects. The behaviour of nAu in the medium changed as the concentration increased. The toxic potential of ionic gold and nAu was expressed as a hazardous concentration where 5% of species will be harmed (HC5). The HC5 for nAu was much higher (42.78 mg/L) compared to the ionic gold (2.44 mg/L). The differences between the hazard potentials of nAu and ionic gold were attributed to the nAu not releasing any Au ions into solution during the exposures and following an aggregation theory response. Exposures to ionic gold on the other hand followed a clear dose dependent response based on the concentration of the ionic metal. Although SSDs present an indication of the relative hazard potential of nanoparticles, the true worth can only be achieved once other nanoparticle characteristics and their behavior in the environment are also considered.

scholarly journals Use of the Species Sensitivity Distribution Approach to Derive Ecological Threshold of Toxicological Concern (eco-TTC) for Pesticides

2021 ◽  
Vol 18 (22) ◽  
pp. 12078
Author(s):  
Cristiana Rizzi ◽  
Sara Villa ◽  
Alessandro Cuzzeri ◽  
Antonio Finizio
Keyword(s):  
Species Sensitivity Distribution ◽  
Toxicity Tests ◽  
Species Sensitivity ◽  
Aquatic Communities ◽  
Ecological Thresholds ◽  
Sensitivity Distribution ◽  
Ecological Threshold ◽  
Hazardous Concentration ◽  
Acute Toxicity Tests ◽  
Experimental Values

The species sensitivity distribution (SSD) calculates the hazardous concentration at which 5% of species (HC5) will be potentially affected. For many compounds, HC5 values are unavailable impeding the derivation of SSD curves. Through a detailed bibliographic survey, we selected HC5 values (from acute toxicity tests) for freshwater aquatic species and 129 pesticides. The statistical distribution and variability of the HC5 values within the chemical classes were evaluated. Insecticides are the most toxic compounds in the aquatic communities (HC5 = 1.4x10−03 µmol L−1), followed by herbicides (HC5 = 3.3 x10−2 µmol L−1) and fungicides (HC5 = 7.8 µmol L−1). Subsequently, the specificity of the mode of action (MoA) of pesticides on freshwater aquatic communities was investigated by calculating the ratio between the estimated baseline toxicity for aquatic communities and the HC5 experimental values gathered from the literature. Moreover, we proposed and validated a scheme to derive the ecological thresholds of toxicological concern (eco-TTC) of pesticides for which data on their effects on aquatic communities are not available. We proposed eco-TTCs for different classes of insecticides, herbicides, and fungicides with a specific MoA, and three eco-TTCs for those chemicals with unavailable MoA. We consider the proposed approach and eco-TTC values useful for risk management purposes.

Estimation of hazardous concentration of toluene in the terrestrial ecosystem through the species sensitivity distribution approach

2021 ◽  
pp. 117836
Author(s):  
Yooeun Chae ◽  
Lia Kim ◽  
Jieun Lee ◽  
Dokyung Kim ◽  
Rongxue Cui ◽  
...  
Keyword(s):  
Terrestrial Ecosystem ◽  
Species Sensitivity Distribution ◽  
Species Sensitivity ◽  
Sensitivity Distribution ◽  
Hazardous Concentration

Multispecies toxicity test for silver nanoparticles to derive hazardous concentration based on species sensitivity distribution for the protection of aquatic ecosystems

2015 ◽  
Vol 10 (5) ◽  
pp. 521-530 ◽  
Author(s):  
Jin Il Kwak ◽  
Rongxue Cui ◽  
Sun-Hwa Nam ◽  
Shin Woong Kim ◽  
Yooeun Chae ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Toxicity Test ◽  
Aquatic Ecosystems ◽  
Species Sensitivity Distribution ◽  
Species Sensitivity ◽  
Sensitivity Distribution ◽  
Hazardous Concentration

Multispecies bioassay of propylparaben to derive protective concentrations for soil ecosystems using a species sensitivity distribution approach

2020 ◽  
Vol 265 ◽  
pp. 114891
Author(s):  
Dokyung Kim ◽  
Lia Kim ◽  
Dasom Kim ◽  
Shin Woong Kim ◽  
Jin Il Kwak ◽  
...  
Keyword(s):  
Species Sensitivity Distribution ◽  
Species Sensitivity ◽  
Sensitivity Distribution ◽  
Soil Ecosystems

scholarly journals Prescribing sea water quality criteria for arsenic, cadmium and lead through species sensitivity distribution

2021 ◽  
Vol 208 ◽  
pp. 111612
Author(s):  
Panneerselvam Karthikeyan ◽  
Shambanagouda. R. Marigoudar ◽  
Dhandapani Mohan ◽  
Krishna Venkatarama Sharma ◽  
M.V. Ramana Murthy
Keyword(s):  
Water Quality ◽  
Sea Water ◽  
Quality Criteria ◽  
Species Sensitivity Distribution ◽  
Water Quality Criteria ◽  
Species Sensitivity ◽  
Sensitivity Distribution ◽  
Cadmium And Lead

scholarly journals QSAR‐Based Estimation of Species Sensitivity Distribution Parameters: An Exploratory Investigation

2019 ◽  
Vol 38 (12) ◽  
pp. 2764-2770 ◽  
Author(s):  
Renske P.J. Hoondert ◽  
Rik Oldenkamp ◽  
Dick Zwart ◽  
Dik Meent ◽  
Leo Posthuma
Keyword(s):  
Species Sensitivity Distribution ◽  
Species Sensitivity ◽  
Sensitivity Distribution ◽  
Exploratory Investigation ◽  
Distribution Parameters
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