Tailoring assistive smart glasses according to pathologies of visually impaired individuals: an exploratory investigation on social needs and difficulties experienced by visually impaired individuals

Recent advances in the field of assistive devices technology represent a great opportunity for improving the quality of life of people with moderate to severe visual impairment. However, it is still unclear what are the precise daily difficulties, needs and expectations of the smart glasses technology for visually impaired individuals. To this aim, we conducted a survey based on three questionnaires to provide qualitative and quantitative insights on those questions across five groups suffering from various visual pathologies ($$N=50$$ N = 50 ). The results clearly showed the importance of developing tailored solutions to fulfill the heterogeneous daily difficulties and needs identified across pathologies. Overall, groups shared similar expectations regarding the assistive smart glasses functionalities in order to improve social interactions.

Reframing Recycling Behaviour through Consumers’ Perceptions: An Exploratory Investigation

Despite the increasing awareness of the consequences of waste, there is no consensus on how and why consumers engage in recycling, making it challenging to design behavioural interventions that might promote recycling, especially in organisational settings. This study is designed to explain consumers’ recycling behaviour and how it differs across contexts, particularly between home and work settings. Using personal accounts of 367 employees from different organisations in the UK, this study explores recycling behaviour at home and work including its motivations and barriers. The findings show that recycling behaviour is different across contexts due to many disparate factors underlying people’s waste generation and recycling behaviours from one context to another. According to the findings, buying and consumption behaviour and waste generation patterns influence the way consumers engage in recycling. The study further demonstrates that contextual factors and individual circumstances are important contributors to consumption behaviour, waste production, and recycling behaviour. While recycling behaviour has been investigated extensively, the findings of this study indicate the need for consumption and waste production patterns to be taken into consideration when designing recycling interventions, enhancing the prospect of a circular economy. This study contributes to theory and practice by associating recycling behaviour with buying and consumption behaviour, including waste generation patterns.

Genomic Epidemiology and Evolution of Scallion Mosaic Potyvirus From Asymptomatic Wild Japanese Garlic

Scallion mosaic virus (ScaMV) belongs to the turnip mosaic virus phylogenetic group of potyvirus and is known to infect domestic scallion plants (Allium chinense) in China and wild Japanese garlic (Allium macrostemon Bunge) in Japan. Wild Japanese garlic plants showing asymptomatic leaves were collected from different sites in Japan during 2012–2015. We found that 73 wild Japanese garlic plants out of 277 collected plants were infected with ScaMV, identified by partial genomic nucleotide sequences of the amplified RT-PCR products using potyvirus-specific primer pairs. Sixty-three ScaMV isolates were then chosen, and those full genomic sequences were determined. We carried out evolutionary analyses of the complete polyprotein-coding sequences and four non-recombinogenic regions of partial genomic sequences. We found that 80% of ScaMV samples have recombination-like genome structure and identified 12 recombination-type patterns in the genomes of the Japanese ScaMV isolates. Furthermore, we found two non-recombinant-type patterns in the Japanese population. Because the wild plants and weeds may often serve as reservoirs of viruses, it is important to study providing the exploratory investigation before emergence in the domestic plants. This is possibly the first epidemiological and evolutionary study of a virus from asymptomatic wild plants.

Serum Metabolomic and Lipidomic Profiling Reveals Novel Biomarkers of Efficacy for Benfotiamine in Alzheimer’s Disease

Serum metabolomics and lipidomics are powerful approaches for discovering unique biomarkers in various diseases and associated therapeutics and for revealing metabolic mechanisms of both. Treatment with Benfotiamine (BFT), a thiamine prodrug, for one year produced encouraging results for patients with mild cognitive impairment and mild Alzheimer’s disease (AD). In this study, a parallel metabolomics and lipidomics approach was applied for the first exploratory investigation on the serum metabolome and lipidome of patients treated with BFT. A total of 315 unique metabolites and 417 lipids species were confidently identified and relatively quantified. Rigorous statistical analyses revealed significant differences between the placebo and BFT treatment groups in 25 metabolites, including thiamine, tyrosine, tryptophan, lysine, and 22 lipid species, mostly belonging to phosphatidylcholines. Additionally, 10 of 11 metabolites and 14 of 15 lipid species reported in previous literature to follow AD progression changed in the opposite direction to those reported to reflect AD progression. Enrichment and pathway analyses show that significantly altered metabolites by BFT are involved in glucose metabolism and biosynthesis of aromatic amino acids. Our study discovered that multiple novel biomarkers and multiple mechanisms that may underlie the benefit of BFT are potential therapeutic targets in AD and should be validated in studies with larger sample sizes.

In Quest of a New AR Technology Application to Enhance the Sustainability of Cultural Tourism: The Olive Heritage in Madeira Through the Looking Glass of a ‘Sandbox’ Approach

This article presents the results of an exploratory investigation looking for new applications of augmented reality (AR) technology to enhance the sustainability of cultural tourism. The ‘sandbox’ approach was initially developed by programmers to experiment innovative solutions in safe conditions, being adopted later in other research areas for the same reason. In this case, the olive heritage at Madeira had been chosen as a background not because it is harmless, but on the contrary, for offering some challenging characteristics. The purpose is to stimulate creativity, forcing thought outside the box. This methodological path will lead to a new concept—the hyperplace of augmented visit (HAV)—conciliating several kinds of attractions in a sustainable way. The general idea is to create a hybrid tour. The user will have the possibility of interacting with a mixture of real objects and digital avatars, virtually reachable by the mediation of AR. The former will be found at the location where the user stands, and the others will be distributed in different areas of the same destination. The study leads to the conclusion that this concept will encourage travellers to spend more time in each spot and to include new points of interest, less popular or even unexplored, in their itinerary, and is also resilient in a context of public health crisis. At the close, HAV's potential will be evaluated and relevant issues mapped to design a suitable working plan to implement a pilot experience.

National Standards: A secondary analysis of the NZCER 2010 Primary and Intermediate Schools National Survey

<p>This thesis describes a secondary analysis of the NZCER 2010 Primary and Intermediate Schools National Survey. The aim of this project was to conduct an exploratory investigation into the attitudes of education stakeholders toward National Standards. Open response data from the NZCER 2010 Primary and Intermediate Schools National Survey principal, teacher, trustee, and parent questionnaires was coded in two different ways. First, a thematic framework was developed and the open responses were coded against the themes. The open responses were then recoded as a binary attitude variable, according to whether they were considered to convey a negative or positive attitude toward the standards. Logistic regression and Fisher’s exact tests were used to determine statistically significant relationships between the binary attitude variable and other elements of the survey data, in the interests of finding predictors for attitude to the National Standards. These analyses were carried out with a selection of items from each of the principal, teacher, and trustee questionnaires; and with all of the items from the parent questionnaire. For teachers and principals (and to a lesser extent, trustees), findings from the thematic analysis of open responses largely reflected concerns about the standards being voiced by sector groups and academics around the time the survey was undertaken. Results from the statistical analysis of the binary attitude variable indicated that principal and teacher attitudes were associated with teaching experience and career plans. General findings from the analysis of parent responses included a suggestion that parents may lack knowledge and understanding of the National Standards, and may be expecting the standards to deliver something they are not designed for. Patterns in parent responses also indicated that attitudes to the National Standards might be related to wider perceptions of the purpose of education, and the various roles of education stakeholders. A similar pattern emerged in analysis of trustee responses. More specific findings related to parent attitude included associations with student year level, and with school reporting practice.</p>