Acute toxicity of Corexit EC9500A and assessment of dioctyl sulfosuccinate as an indicator for monitoring four oil dispersants applied to diluted bitumen

2018 ◽  
Vol 37 (5) ◽  
pp. 1309-1319 ◽  
Author(s):  
Ceara Y. MacInnis ◽  
Pamela Brunswick ◽  
Grace H. Park ◽  
Craig Buday ◽  
Grant Schroeder ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Oil Dispersants ◽  
Dioctyl Sulfosuccinate ◽  
Corexit Ec9500a

Acute toxicity of oil dispersants to marine fish larvae

1977 ◽  
Vol 40 (1) ◽  
pp. 65-74 ◽  
Author(s):  
K. W. Wilson
Keyword(s):  
Acute Toxicity ◽  
Marine Fish ◽  
Fish Larvae ◽  
Oil Dispersants ◽  
Marine Fish Larvae

The acute toxicity of three oil dispersants

1986 ◽  
Vol 41 (1) ◽  
pp. 23-31 ◽  
Author(s):  
E.O. Oyewo
Keyword(s):  
Acute Toxicity ◽  
Oil Dispersants

Acute toxicity of several oil dispersants towards the green algae Chlamydomonas and Dunaliella

Chemosphere ◽  
1978 ◽  
Vol 7 (3) ◽  
pp. 247-255 ◽  
Author(s):  
Mikal Heldal ◽  
Svein Norland ◽  
Torleiv Lien ◽  
Gjert Knutsen
Keyword(s):  
Acute Toxicity ◽  
Green Algae ◽  
Oil Dispersants

Comparative Study to Determine the Biodegradability of Dispersants at Environmentally Relevant Concentrations

2017 ◽  
Vol 2017 (1) ◽  
pp. 331-346
Author(s):  
Yu Zhang ◽  
Mobing Zhuang ◽  
Pablo Campo ◽  
Ruta Suresh Deshpande ◽  
Devi Sundaravadivelu ◽  
...  
Keyword(s):  
Bacterial Community Composition ◽  
Volume Ratio ◽  
Pcr Analysis ◽  
Oil Dispersants ◽  
Corexit 9500 ◽  
Dispersed Oil ◽  
Oil Concentration ◽  
The Media ◽  
Dioctyl Sulfosuccinate ◽  
Alaskan North Slope

ABSTRACT Chemical dispersant agents reduce the interfacial tension between oil and water, and increase the surface area to volume ratio of oil droplets thus facilitating the biodegradation of spilled oil. Dispersants are composed of surface active molecules known as surfactants and various commercial products contain Dioctyl Sulfosuccinate (DOSS) as the active surfactant ingredient. Since previous laboratory studies were conducted at oil and dispersant concentrations significantly higher (~0.7 g/L oil with Dispersant to Oil Ratio (DOR) of 1:25) than those typically found in field conditions, experiments were conducted at low levels of oil and dispersant (28 μg/L oil with DOR of 1:25) in order to determine the degradation trends at environmentally relevant concentrations. Experiments were conducted using two crude oils (Alaskan North Slope (ANS) and Endicott) and two dispersant products (Corexit 9500 and Finasol OSR 52) to study the biodegradation of dispersants and dispersed oil and oil alone samples were used as controls. Two oil degrading cultures, isolated from the surface (meso) and deep sea (cryo) of the Gulf of Mexico, were enriched on crude oil at 25 and 5 °C and were used as the inocula. The biodegradation experiments were performed at 5 °C for 56 days and at 25 °C for 48 days using sterile GP2 artificial seawater as the media. The time series concentration of DOSS, the primary surfactant in the dispersants was monitored using LC-MS/MS in addition to the oil concentration which was measured using GC-MS/MS. Although the initial concentration of DOSS in Finasol OSR 52 was 20% higher than in Corexit 9500, over 95% of the anionic surfactant fraction was metabolized for both types of dispersant products by the end of the experiment at 25 °C while it persisted at 5 °C. The effect of dispersant and oil type on microbial community structure was also analyzed using PCR analysis. Results indicated that the abundance of Thalassospira correlated well with hydrocarbon degradation trends. The results from this study significantly expands on our understanding of biodegradation of DOSS, dispersed, and non-dispersed oil and also provides information regarding bacterial community composition.

The Toxicity Profile of a Single Dose of Paroxetine: An Alternative Approach to Acute Toxicity Testing in the Rat

2001 ◽  
Vol 88 (2) ◽  
pp. 59-66 ◽  
Author(s):  
Pauline M. Ryan ◽  
John P. Kelly1Note ◽  
Philip L. Chambers ◽  
Brian E. Leonard
Keyword(s):  
Single Dose ◽  
Acute Toxicity ◽  
Toxicity Testing ◽  
Toxicity Profile ◽  
Alternative Approach ◽  
Acute Toxicity Testing

Acute and sub-acute toxicity methanolic extract from Brickellia cavanillesii in mice

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
GM Avila-Villarreal ◽  
DE Giles-Rivas ◽  
B Aguilar-Guadarrama ◽  
P Castillo-España ◽  
S Estrada-Soto
Keyword(s):  
Acute Toxicity ◽  
Methanolic Extract

Initial Studies of a Potent Antiheparin Agent (Ubiquin®)

1968 ◽  
Vol 20 (03/04) ◽  
pp. 588-595 ◽  
Author(s):  
E. B Goodsell ◽  
R. A Krause ◽  
E. T Kimura
Keyword(s):  
Side Effects ◽  
Acute Toxicity ◽  
Propylene Oxide ◽  
Toluidine Blue ◽  
Water Soluble ◽  
Per Se

SummaryUbiquin (oligo-3-(N-methylmorpholinium)-l,2-propylene oxide chloride) is a stable, water soluble, active heparin antagonist producing prompt neutralization when administered in a 1:1 ratio to rats and dogs. Initial studies indicate that it is devoid of any effect on coagulation per se; nor are there any obvious side effects manifested during the process of neutralization. The acute toxicity is less than that of other compounds in use: toluidine blue, protamine and hexadimethrine.

Determination of acute toxicity of Tiacyclin solution for injection in laboratory animals

2019 ◽  
Vol 331 (8) ◽  
pp. 25-27
Author(s):  
N.Y. Morozov ◽  
◽  
S.I. Tchukina ◽  
E.I. Koveshnikova ◽  
◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Laboratory Animals
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