scholarly journals RREB1‐MKL2 fusion in a spindle cell sinonasal sarcoma: Biphenotypic sinonasal sarcoma or ectomesenchymal chondromyxoid tumor in unusual site?

Author(s):  
Gunhild Mechtersheimer ◽  
Mindaugas Andrulis ◽  
Klaus‐Wolfgang Delank ◽  
Anna‐Lena Volckmar ◽  
Lei Zhang ◽  
...  

2019 ◽  
Vol 6 (1) ◽  
pp. 32
Author(s):  
Ryan Yu ◽  
Brigitte Courteau ◽  
Ryan Rebello ◽  
Alice Lytwyn ◽  
Monalisa Sur ◽  
...  

Female adnexal tumor of probable wolffian origin (FATWO) is a tumor of low malignant potential that arises predominantly in the broad ligament, mesosalpinx, and ovarian hilus. The rarity of FATWO increases its susceptibility to misdiagnosis as other tumors, especially when it occurs at an unusual site. We report a 29-year-old woman with a 7.2 cm left paravaginal FATWO that invaded into the vaginal lumen. The initial biopsy demonstrated features suggestive of vaginal spindle cell epithelioma, but with increased Ki67 proliferation index. Pathologists should be aware that the common sieve-like architecture of FATWO may not be apparent on small biopsies, which by sampling error may demonstrate predominantly the less common spindle cell architecture. Awareness of FATWO in the differential diagnosis of paravaginal tumors may help to avoid misinterpretation as vaginal spindle cell epithelioma, a previously unappreciated pitfall in the diagnosis of FATWO.



2005 ◽  
Vol 84 (6) ◽  
pp. 362-365 ◽  
Author(s):  
Himani Lade ◽  
Neelima Gupta ◽  
P.P. Singh ◽  
Geeta Dev

Spindle-cell hemangioendothelioma is an uncommon vascular lesion that exhibits a predilection for the extremities. Very few reports have been published describing this lesion in the head and neck, and to the best of our knowledge, its occurrence in the oropharynx has not been previously reported. In addition to reporting an unusual site of this lesion, our rationale for publishing this case is to comment on the diagnostic dilemma that arose in view of an unclear clinicohistopathologic pattern and to discuss this lesion's similarity to other aggressive tumors.



Author(s):  
Anu Anna Jacob ◽  
Geethanjali N. ◽  
Usha Poothiode

Pleomorphic lipoma/ spindle cell lipoma accounts for 15 % of lipoma within extremities, confining to the superficial plain comprising lower dermis and subcutaneous tissue. Intramuscular presentation in extrimities is a rare presentation. Here is a case of deep seated pleomorphic lipoma, of forearm, both on fine needle aspiration, biopsy and IHC confirmation. 100% of benign cases of lipoma are positive for CD 34, as stated in many studies and was also positive in our case.



Author(s):  
Irving Dardick

With the extensive industrial use of asbestos in this century and the long latent period (20-50 years) between exposure and tumor presentation, the incidence of malignant mesothelioma is now increasing. Thus, surgical pathologists are more frequently faced with the dilemma of differentiating mesothelioma from metastatic adenocarcinoma and spindle-cell sarcoma involving serosal surfaces. Electron microscopy is amodality useful in clarifying this problem.In utilizing ultrastructural features in the diagnosis of mesothelioma, it is essential to appreciate that the classification of this tumor reflects a variety of morphologic forms of differing biologic behavior (Table 1). Furthermore, with the variable histology and degree of differentiation in mesotheliomas it might be expected that the ultrastructure of such tumors also reflects a range of cytological features. Such is the case.



2015 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Shahnoor Islam ◽  
AKM Amirul Morshed ◽  
Afiqul Islam

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)



2008 ◽  
Vol 59 (1) ◽  
pp. 45
Author(s):  
Jee Young Lee ◽  
Kyung Jin Suh ◽  
Sang Yoon Kim


Author(s):  
Carlos Marques Pontinha ◽  
Manuela Mafra ◽  
Luis Cerqueira ◽  
Amets Sagarribay ◽  
Fernando Fonseca ◽  
...  


2019 ◽  
Author(s):  
Lilla Krokker ◽  
Gabor Nyirő ◽  
Lilla Reininger ◽  
Otto Darvasi ◽  
Nikolette Szucs ◽  
...  


Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.



2004 ◽  
Vol 55 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Koji Kudo ◽  
Tatsuya Fujiyoshi ◽  
Tetsuro Wakasugi


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