Preparation, characterization, release kinetics, andin vitrocytotoxicity of calcium silicate cement as a risedronate delivery system

2013 ◽  
Vol 102 (7) ◽  
pp. 2295-2304 ◽  
Author(s):  
Tianxing Gong ◽  
Zhiqin Wang ◽  
Yubiao Zhang ◽  
Changshan Sun ◽  
Quanzu Yang ◽  
...  
2006 ◽  
Vol 3 (4) ◽  
pp. 367-372 ◽  
Author(s):  
Ashish Jain ◽  
Sunil Jain ◽  
Awesh Yadav ◽  
Govind Agrawal

Author(s):  
Mariano S. Pedano ◽  
Kumiko Yoshihara ◽  
Xin Li ◽  
Bernardo Camargo ◽  
Kirsten Van Landuyt ◽  
...  

2017 ◽  
Vol 116 (9) ◽  
pp. 679-688 ◽  
Author(s):  
Yuan-Chien Chen ◽  
Ming-You Shie ◽  
Yuan-Haw Andrew Wu ◽  
Kai-Xing Alvin Lee ◽  
Li-Ju Wei ◽  
...  

2001 ◽  
Vol 27 (10) ◽  
pp. 1073-1081 ◽  
Author(s):  
Lise Sylvest Nielsen ◽  
Lise Sylvest Helledi ◽  
Lene Schubert

2016 ◽  
Vol 23 (4) ◽  
pp. 375-380
Author(s):  
P. Manohar Reddy ◽  
Ravy Lakshmi ◽  
Febin Prabhu Dass ◽  
Swamiappan Sasikumar

AbstractSodium calcium silicate (Na2CaSiO4) is a bioactive silicate with Na2O, CaO and SiO2 as its basic components, which is similar to that of the composition of bioactive glasses. In the present study, pure sodium calcium silicate was synthesized by rapid combustion technique, and the synthesized sample was characterized by powder X-ray diffraction to check the phase purity. The scaffolds were prepared by varying the ratio of sodium calcium silicate and polyvinyl alcohol, and the apatite-formation ability of the scaffolds was examined by soaking them in a simulated body fluid. The results revealed the formation of hydroxyapatite on the surface of the scaffold after 5 days, which is found to be rapid when compared with the bioactivity of the calcium silicates and calcium magnesium silicates. The scaffolds were also loaded with ciprofloxacin as a model drug and analyzed for its drug release profile using UV spectrophotometer. The release profile did not vary with the change in bioceramic-to-biopolymer ratio, and 60% of the drug was released in 10 days, which is within the appreciable range for a targeted drug delivery system. Moreover, the experimental and simulated values of the release kinetics were compared by applying the existing mathematical model.


Biomatter ◽  
2011 ◽  
Vol 1 (1) ◽  
pp. 76-80 ◽  
Author(s):  
Cecilia Persson ◽  
Håkan Engqvist

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
S. Koubi ◽  
H. Elmerini ◽  
G. Koubi ◽  
H. Tassery ◽  
J. Camps

This study compared thein vitromarginal integrity of open-sandwich restorations based on aged calcium silicate cement versus resin-modified glass ionomer cement. Class II cavities were prepared on 30 extracted human third molars. These teeth were randomly assigned to two groups () to compare a new hydraulic calcium silicate cement designed for restorative dentistry (Biodentine, Septodont, Saint Maur des Fossés, France) with a resin-modified glass ionomer cement (Ionolux, Voco, Cuxhaven, Germany) in open-sandwich restorations covered with a light-cured composite. Positive () and negative () controls were included. The teeth simultaneously underwent thermocycling and mechanocycling using a fatigue cycling machine (1,440 cycles, 5–55°C; 86,400 cycles, 50 N/cm2). The specimens were then stored in phosphate-buffered saline to simulate aging. After 1 year, the teeth were submitted to glucose diffusion, and the resulting data were analyzed with a nonparametric Mann-Whitney test. The Biodentine group and the Ionolux group presented glucose concentrations of 0.074 ± 0.035 g/L and 0.080 ± 0.032 g/L, respectively. No statistically significant differences were detected between the two groups. Therefore, the calcium silicate-based material performs as well as the resin-modified glass ionomer cement in open-sandwich restorations.


2020 ◽  
Vol 117 ◽  
pp. 111297 ◽  
Author(s):  
I-Ting Wu ◽  
Pan-Fu Kao ◽  
Yun-Ru Huang ◽  
Shinn-Jyh Ding

2010 ◽  
Vol 150 ◽  
pp. 465-465
Author(s):  
Maria Giovanna Gandolfi ◽  
Andrea Colin ◽  
Giovanni Luca Acquaviva ◽  
Stefano Chersoni ◽  
Fabio Fava ◽  
...  

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