Novel Fluoride-doped Calcium-silicate cement for dental applications. The effect of Bi2O3 and BaSO4 radiopacifier agents on setting time

The objective of the paper is to investigate the mechanical and the handling properties of a novel injectable bone void filler based on calcium silicate. The orthopaedic cement based on calcium silicate was compared to a calcium phosphate cement, Norian SRS from Syntes Stratec, with regard to the working (ejection through 14 G needle) and setting time (Gillmore needles), Young’s modulus and the flexural (ASTM F-394) and compressive (ISO 9917) strength after storage in phosphate buffer saline at body temperature for time points from 1h up to 16 weeks. The calcium silicate cement is composed of a calcium silicate powder (grain size below 20 µm) that is mixed with a liquid (water and CaCl2) into a paste using a spatula and a mixing cup. The water to cement ratio used was about 0.5. The calcium silicate had a working time of 15 minutes and a setting time of 17 minutes compared to 5 and 10 minutes respectively for the calcium phosphate cement. The compressive strength was considerably higher for the calcium silicate cement (>100 MPa) compared to the calcium phosphate cement (>40 MPa). Regarding the flexural strength the calcium silicate cement had high values for up to 1 week (> 40 MPa) but it decreased to 25 MPa after 16 weeks. The phosphate cement had a constant flexural strength of about 25 MPa. The results show that calcium silicate cement has the mechanical and handling potential to be used as high strength bone void filler.

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Physicochemical and Biological Properties of Mg-Doped Calcium Silicate Endodontic Cement

Materials ◽

10.3390/ma14081843 ◽

2021 ◽

Vol 14 (8) ◽

pp. 1843

Author(s):

Kyung-Hyeon Yoo ◽

Yong-Il Kim ◽

Seog-Young Yoon

Keyword(s):

Mechanical Properties ◽

Calcium Silicate ◽

Setting Time ◽

Sol Gel ◽

Biological Properties ◽

Hydration Properties ◽

Calcium Silicate Cement ◽

Fourier Transformed Infrared Spectroscopy ◽

Physicochemical And Biological Properties ◽

Mg Doped

Calcium silicate-based cement has been widely used for endodontic repair. However, it has a long setting time and needs to shorten setting time. This study investigated the effects of magnesium (Mg) ion on the setting reaction, mechanical properties, and biological properties of calcium silicate cement (CSC). Sol-gel route was used to synthesize Mg ion-doped calcium silicate cement. Synthesized cement was formulated with the addition of different contents of Mg ion, according to 0, 1, 3, 5 mol% of Mg ion-doped calcium silicate. The synthesized cements were characterized with X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FT-IR), and scanning electron microscopy (SEM). We also evaluated the physicochemical and biological properties of cement, such as the setting time, compressive strength, micro-hardness, simulated body fluid (SBF) immersion, cytotoxicity, and cell differentiation tests. As a result, the Mg ion improves the hydration properties of calcium silicate cement, and the setting time is reduced by increasing the amounts of Mg ion. However, the mechanical properties deteriorated with increasing Mg ion, and 1 and 3 mol% Mg-doped calcium silicate had appropriate mechanical properties. Also, the results of biological properties such as cytotoxicity, ALP activity, and ARS staining improved with Mg ion. Consequently, the optimal condition is 3 mol% of Mg ion-doped calcium silicate (3%Mg-CSC).

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A novel sol-gel-derived calcium silicate cement with short setting time for application in endodontic repair of perforations

International Journal of Nanomedicine ◽

10.2147/ijn.s150198 ◽

2018 ◽

Vol Volume 13 ◽

pp. 261-271 ◽

Cited By ~ 15

Author(s):

Bor-Shiunn Lee ◽

Hong-Ping Lin ◽

Jerry Chun Chung Chan ◽

Wei-Chuan Wang ◽

Ping-Hsuan Hung ◽

...

Keyword(s):

Calcium Silicate ◽

Setting Time ◽

Sol Gel ◽

Calcium Silicate Cement ◽

Short Setting Time

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Physico-Chemical Investigation of Endodontic Sealers Exposed to Simulated Intracanal Heat Application: Hydraulic Calcium Silicate-Based Sealers

Materials ◽

10.3390/ma14040728 ◽

2021 ◽

Vol 14 (4) ◽

pp. 728

Author(s):

David Donnermeyer ◽

Magdalena Ibing ◽

Sebastian Bürklein ◽

Iris Weber ◽

Maximilian P. Reitze ◽

...

Keyword(s):

Heat Treatment ◽

Thermal Treatment ◽

Film Thickness ◽

Physical Properties ◽

Calcium Silicate ◽

Setting Time ◽

Chemical Properties ◽

Chemical Changes ◽

Time Flow ◽

Heat Application

The aim of this study was to gain information about the effect of thermal treatment of calcium silicate-based sealers. BioRoot RCS (BR), Total Fill BC Sealer (TFBC), and Total Fill BC Sealer HiFlow (TFHF) were exposed to thermal treatment at 37 °C, 47 °C, 57 °C, 67 °C, 77 °C, 87 °C and 97 °C for 30 s. Heat treatment at 97 °C was performed for 60 and 180 s to simulate inappropriate application of warm obturation techniques. Thereafter, specimens were cooled to 37 °C and physical properties (setting time/flow/film thickness according to ISO 6876) were evaluated. Chemical properties (Fourier-transform infrared spectroscopy) were assessed after incubation of the specimens in an incubator at 37 °C and 100% humidity for 8 weeks. Statistical analysis of physical properties was performed using the Kruskal-Wallis-Test (P = 0.05). The setting time, flow, and film thickness of TFBC and TFHF were not relevantly influenced by thermal treatment. Setting time of BR decreased slightly when temperature of heat application increased from 37 °C to 77 °C (P < 0.05). Further heat treatment of BR above 77 °C led to an immediate setting. FT-IR spectroscopy did not reveal any chemical changes for either sealers. Thermal treatment did not lead to any substantial chemical changes at all temperature levels, while physical properties of BR were compromised by heating. TFBC and TFHF can be considered suitable for warm obturation techniques.

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Experimental resin-modified calcium-silicate cement containing N-(2-hydroxyethyl) acrylamide monomer for pulp tissue engineering

Materials Science and Engineering C ◽

10.1016/j.msec.2021.112105 ◽

2021 ◽

pp. 112105

Author(s):

Mariano S. Pedano ◽

Kumiko Yoshihara ◽

Xin Li ◽

Bernardo Camargo ◽

Kirsten Van Landuyt ◽

...

Keyword(s):

Tissue Engineering ◽

Calcium Silicate ◽

Pulp Tissue ◽

Calcium Silicate Cement ◽

Acrylamide Monomer

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Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement

Journal of the Formosan Medical Association ◽

10.1016/j.jfma.2017.06.005 ◽

2017 ◽

Vol 116 (9) ◽

pp. 679-688 ◽

Cited By ~ 15

Author(s):

Yuan-Chien Chen ◽

Ming-You Shie ◽

Yuan-Haw Andrew Wu ◽

Kai-Xing Alvin Lee ◽

Li-Ju Wei ◽

...

Keyword(s):

Calcium Silicate ◽

Calcium Silicate Cement ◽

Anti Inflammation

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Influence of Powder-to-Gel Ratio on Physicochemical Properties of a Calcium Silicate Sealer

Odovtos - International Journal of Dental Sciences ◽

10.15517/ijds.2020.42998 ◽

2020 ◽

pp. 337-345

Author(s):

Fernanda F. E. Torres ◽

Patricia Perinoto ◽

Roberta Bosso-Martelo ◽

Gisselle M. Chávez-Andrade ◽

Juliane M. Guerreiro-Tanomaru ◽

...

Keyword(s):

Physicochemical Properties ◽

Calcium Silicate ◽

Setting Time ◽

Repair Material ◽

Alkaline Ph ◽

Root Canal Sealer ◽

Work Time ◽

Lower Solubility ◽

Low Solubility ◽

One Way Anova

Differences in liquid-to-powder ratio can affect the properties of calcium silicate-based materials. This study assessed the influence of powder-to-gel ratio on physicochemical properties of NeoMTA Plus. Setting time (minutes), flow (mm and mm²), pH (at different periods), radiopacity (mm Al) and solubility (% mass loss) were evaluated using the consistencies for root repair material (NMTAP-RP; 3 scoops of powder to 2 drops of gel) and root canal sealer (NMTAP-SE; 3 scoops of powder to 3 drops of gel), in comparison to Biodentine cement (BIO) and TotalFill BC sealer (TFBC). Statistical analysis was performed using one-way ANOVA and Tukey tests (α=0.05). BIO had the shortest setting time, followed by NMTAP-RP and NMTAP-SE. TFBC showed the highest setting time and radiopacity. BIO, NMTAP-RP, and NMTAP-SE had similar radiopacity. All materials promoted an alkaline pH. NMTAP-RP/SE presented lower solubility than BIO and TFBC. Regarding the flow, TFBC had the highest values, followed by NMTAP-SE, and NMTAP-RP. BIO had the lowest flow. In conclusion, NMTAP in both powder-to-gel ratios showed high pH and low solubility. The increase in the powder ratio decreased the setting time and flow. These findings are important regarding the proper consistency and work time to clinical application.

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Premixed calcium silicate cement for endodontic applications

Biomatter ◽

10.4161/biom.1.1.16735 ◽

2011 ◽

Vol 1 (1) ◽

pp. 76-80 ◽

Cited By ~ 9

Author(s):

Cecilia Persson ◽

Håkan Engqvist

Keyword(s):

Calcium Silicate ◽

Calcium Silicate Cement

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Comparative Assessment of Effectiveness of Calcium Silicate Dispersions Produced Using Sucrose and Lactose as Components of Composite Cement Binder

Materials Science Forum ◽

10.4028/www.scientific.net/msf.1017.11 ◽

2021 ◽

Vol 1017 ◽

pp. 11-20

Author(s):

Evgeny A. Shoshin ◽

Valeria V. Strokova ◽

Zheng Mao Ye

Keyword(s):

Specific Surface ◽

Surface Area ◽

Specific Surface Area ◽

Calcium Silicate ◽

Setting Time ◽

Inhibitory Effect ◽

Main Element ◽

Residual Content ◽

Nucleation Effect ◽

Wide Range

Silicate micro- and nano-additives are multifunctional in relation to cement systems. Their application can solve a wide range of technological problems while maintaining the economic efficiency of technical solutions. The effect of silicate additives and fillers is determined by their level of dispersion, due to which the technologies for producing nano- and submicro-sized dispersed materials are being developed. The combination of mechanochemical synthesis of modified calcium hydrosilicates with subsequent thermolysis makes it possible to produce calcium silicate dispersions (SCD), which differ in polymodality of the fractional composition including submicro (10–7–10–6 m) and microdimensional (≥10–6 m) modes. The main element of the technology is the use of modifying carbohydrate, which acts as a stabilizer of hydrated phases of silicates. A comparative study of SCD produced using sucrose (sSCD) and lactose (lSCD) revealed the effect of these carbohydrates on the properties of sSCD and lSCD, as well as their effectiveness as a component of cementitious composite binder. It was found that the level of adsorption of modifying carbohydrate determines the physical properties of SCD (granulometry, specific surface area). The relatively high residual content of free sucrose (0.24%) in the composition of sSCD prevents the consolidation of silicates nanoparticles formed during the thermolysis, causes a high content of submicro sized fractions and a high specific surface area with sSCD (26.3 ± 0.7 m2/g). Lactose is absorbed by the silicate phase; the residual content of free lactose does not exceed 0.028% of lSCD. The low content of stabilizing carbohydrate contributes to the development of nanoparticle consolidation, a decrease in the specific surface area of lSCD to 13.0 ± 0.2 m2/g and content of submicrosized fractions. The residual content of free carbohydrates and particle size characteristics of sSCD and lSCD determine the nature of their influence on Cement-SCD-based concrete setting and hardening. The presence of residual sucrose in the composition of sSCD and fine fractions determines the competitive nature of the processes of retardation of hardening and acceleration of hardening of the cement system due to the nucleation effect, as a result of which the curve of the setting time is extreme. In addition, the inhibitory effect of sucrose reduces the strength of concrete on the 7th day. By the 28th day, the inhibitory effect of sucrose has been overcome, and concrete samples demonstrate an 18% increase in compressive strength with a sSCD content of 30%. The low content of residual free lactose in the composition of lSCD causes the nucleation effect. As a result, there is a monotonous reduction in the setting time of concrete mix with an increase in the content of lSCD in the composition of HF, as well as a significant increase in concrete strength (up to 127%) on the 7th day. At the same time, on the 28th day the strength of concrete increases slightly

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Quantitative Evaluation by Glucose Diffusion of Microleakage in Aged Calcium Silicate-Based Open-Sandwich Restorations

International Journal of Dentistry ◽

10.1155/2012/105863 ◽

2012 ◽

Vol 2012 ◽

pp. 1-6 ◽

Cited By ~ 29

Author(s):

S. Koubi ◽

H. Elmerini ◽

G. Koubi ◽

H. Tassery ◽

J. Camps

Keyword(s):

Calcium Silicate ◽

Glass Ionomer Cement ◽

Glass Ionomer ◽

Calcium Silicate Cement ◽

Resin Modified Glass Ionomer ◽

Glucose Diffusion ◽

Negative Controls ◽

Phosphate Buffered Saline ◽

Ionomer Cement

This study compared thein vitromarginal integrity of open-sandwich restorations based on aged calcium silicate cement versus resin-modified glass ionomer cement. Class II cavities were prepared on 30 extracted human third molars. These teeth were randomly assigned to two groups () to compare a new hydraulic calcium silicate cement designed for restorative dentistry (Biodentine, Septodont, Saint Maur des Fossés, France) with a resin-modified glass ionomer cement (Ionolux, Voco, Cuxhaven, Germany) in open-sandwich restorations covered with a light-cured composite. Positive () and negative () controls were included. The teeth simultaneously underwent thermocycling and mechanocycling using a fatigue cycling machine (1,440 cycles, 5–55°C; 86,400 cycles, 50 N/cm2). The specimens were then stored in phosphate-buffered saline to simulate aging. After 1 year, the teeth were submitted to glucose diffusion, and the resulting data were analyzed with a nonparametric Mann-Whitney test. The Biodentine group and the Ionolux group presented glucose concentrations of 0.074 ± 0.035 g/L and 0.080 ± 0.032 g/L, respectively. No statistically significant differences were detected between the two groups. Therefore, the calcium silicate-based material performs as well as the resin-modified glass ionomer cement in open-sandwich restorations.

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