Action of mustard gas and other poisons on yeast cells. VI. Study of the relationship between inhibition of carbohydrate metabolism and inhibition of growth by various poisons, and effects of other toxic agents on yeast

1947 ◽  
Vol 30 (1) ◽  
pp. 31-42 ◽  
Author(s):  
V. Everett Kinsey ◽  
W. Morton Grant
1924 ◽  
Vol 70 (2) ◽  
pp. 333-343 ◽  
Author(s):  
Frank N. Allan ◽  
B. R. Dickson ◽  
J. Markowitz

Author(s):  
Gholamreza Farnoosh ◽  
Mostafa Ghanei ◽  
Hossein Khorramdelazad ◽  
Gholamhossein Alishiri ◽  
Alireza Jalali Farahani ◽  
...  

ABSTRACT Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged as a health problem worldwide. It seems that COVID-19 is more lethal for Iranian veterans with a history of exposure to mustard gas. There are some similarities in the pathogenesis of SARS-CoV-2 and mustard gas in immune system disruption and pulmonary infection. SARS-CoV-2 and mustard gas inducing oxidative stress, immune system dysregulation, cytokine storm, and overexpression of angiotensin-converting enzyme II (ACE2) receptor in lungs that act as functional entry receptors for SARS-CoV-2. Moreover, Iranian survivors of mustard gas exposure are more susceptible and vulnerable to COVID-19. It is suggested that the principles of COVID-19 infection prevention and control be adhered to more stringently in Iranian survivors of mustard gas exposure than others who have not been exposed to mustard gas. Therefore, in this review, we discuss the different pathologic aspects of lung injury caused by mustard gas and also the relationship between this damage and the increased susceptibility of Iranian mustard gas exposed survivors to COVID-19.


1989 ◽  
Vol 5 (2) ◽  
pp. 247-260 ◽  
Author(s):  
Stata Norton

Association between functional damage and damage to the central nervous system from toxic agents can be used to determine the value of behavioral tests as predictors of damage to the nervous system. Variability in data from behavioral tests may be caused, in part, by varying levels of structural differences in the nervous system. Stepwise multiple regression is one method for analyzing the relationship between variability in data resulting from linkage between functional and morphological or other parameters of the structure of the nervous system. As an example, the predictive value of four behavioral tests is assessed in detecting thinning of the cerebral cortex following gestational exposure of rats to ionizing radiation. In this analysis, there were seven independent variables for predicting cortical thickness. The sequence of number of times each variable was used in prediction, from most frequent to least frequent, was: angle of stride > negative geotaxis > continuous corridor> body weight > width of stride > length of stride > reflex suspension. The data support the concept that there are varying degrees of predictive associations between these functional and cortical parameters.


Author(s):  
Axel Athané ◽  
Anthony Buisson ◽  
Marion Challier ◽  
Florian Beaumatin ◽  
Stéphen Manon ◽  
...  
Keyword(s):  

1962 ◽  
Vol 7 (4) ◽  
pp. 257-258
Author(s):  
L. KOVáč ◽  
Vlasta Kováčová
Keyword(s):  

1973 ◽  
Vol 80 (3) ◽  
pp. 503-509 ◽  
Author(s):  
H. J. Swatland ◽  
R. G. Cassens

SummaryEighteen foetal sheep were used to study the relationship between suboptimal growth and linear size of skeletal units, dry weights of representative muscles and muscle histology. Foetuses with suboptimal growth caused by inadequate maternal nutrition and competition with other foetuses showed a decrease in skeletomuscular growth although allometric growth was not affected. A slight correlation (r =0·14, P < 0·005) existed between dry weight of the longissimus dorsi and mean minimum myofibre diameter. On morphological evidence, myofibre hyperplasia was thought to be complete by approximately 80 days gestation in all foetuses. Increases in the number of myofibres crossing mid-length transverse sections of the sartorius occurred after this time but were thought to be due to intrafascicularly terminating myofibres growing in length. Suboptimal muscle growth of foetuses in the latter third of gestation was thought to be associated with an inhibition of growth in length of intrafascicularly terminating myofibres.


1933 ◽  
Vol 16 (4) ◽  
pp. 571-577 ◽  
Author(s):  
J. M. Nelson ◽  
B. G. Wilkes

1. The relationship of sucrose and water concentration to invertase activity in vivo and in vitro has been studied under the same environmental conditions. 2. The sucroclastic activity of S. cerevisiae cells and of invertase solutions prepared from them reacts to changes in sucrose and water concentration in an identical manner. 3. The invertase contained in living yeast cells is just as freely exposed to the conditions of sucrose and water concentrations of the suspending medium as it would be if it were contained in a cell-free solution. Weight is added to the previous suggestion (2) that yeast invertase exerts its physiological activity in a region quite close to the surface of the cell.


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