Fluoride release and remineralizing potential of varnishes in early caries lesions in primary teeth

2020 ◽  
Author(s):  
Aline Laignier Soares‐Yoshikawa ◽  
Thais Varanda ◽  
Alexsandra Shizue Iwamoto ◽  
Kamila Rosamilia Kantovitz ◽  
Regina Maria Puppin‐Rontani ◽  
...  
Keyword(s):  
Primary Teeth ◽  
Fluoride Release ◽  
Early Caries ◽  
Caries Lesions

scholarly journals An In Vitro Investigation of Anticaries Efficacy of Fluoride Varnishes

2019 ◽  
Vol 44 (5) ◽  
pp. E234-E243 ◽  
Author(s):  
L Al Dehailan ◽  
EA Martinez-Mier ◽  
GJ Eckert ◽  
F Lippert
Keyword(s):  
Artificial Saliva ◽  
Acid Resistance ◽  
Fluoride Release ◽  
In Vitro Investigation ◽  
Ph Cycling ◽  
Baseline Values ◽  
Bovine Enamel ◽  
Early Caries ◽  
Caries Lesions

SUMMARY Most currently marketed fluoride varnishes (FVs) have not been evaluated for their effectiveness in preventing dental caries. The objective of this study was to investigate the anticaries efficacy, measured as fluoride release into artificial saliva (AS); change in surface microhardness of early enamel caries lesions; and enamel fluoride uptake (EFU) of 14 commercially available FVs and two control groups. Bovine enamel specimens (5×5 mm) were prepared and assigned to 18 groups (n=12). Early caries lesions were created in the specimens and characterized using Vickers microhardness (VHNlesion). FV was applied to each group of specimens. Immediately afterward, specimens were incubated in 4 mL of AS for 18 hours, which were collected and renewed every hour for the first six hours. AS samples were analyzed for fluoride using an ion-specific electrode. Specimens were then brushed for 20 seconds with toothpaste slurry and subjected to pH cycling consisting of a four-hour/day acid challenge and one-minute treatments with 1100 ppm F dentifrice for five days. Microhardness was measured following pH cycling (VHNpost). EFU was determined using microbiopsy. Acid resistance (eight-hour demin challenge) was performed after pH cycling, and microhardness was measured (VHNart) and compared with baseline values to test the FV impact after pH cycling. One-way analysis of variance was used for data analysis (α=0.05). FVs differed in their release characteristics (mean ± SD ranged from 14.97 ± 2.38 μg/mL to 0.50 ± 0.15 μg/mL), rehardening capability (mean ± SD ranged from 24.3 ± 15.1 to 11.7 ± 12.7), and ability to deliver fluoride to demineralized lesions (mean ± SD ranged from 3303 ± 789 μg/cm3 to 707 ± 238 μg/cm3). Statistically significant but weak linear associations were found between ΔVHN(post – lesion), EFU, and fluoride release (correlations 0.21-0.36). The results of this study demonstrated that differences in FV composition can affect their efficacy in in vitro conditions.

scholarly journals Evaluation of the Maternal Perception of the Oral Health of the Inpatient Infant

2017 ◽  
Vol 15 (3) ◽  
pp. 205
Author(s):  
Ana de Lourdes Sá de Lira ◽  
Joyce de Moura Crisóstomo ◽  
Sylvana Thereza de Castro Pires Rebelo
Keyword(s):  
Health Care ◽  
Oral Health ◽  
Oral Hygiene ◽  
Public Hospital ◽  
Primary Teeth ◽  
Baby Bottle ◽  
Dental Practitioners ◽  
Early Caries ◽  
Caries Lesions ◽  
Over Time

Aim: To evaluate the mother’s perception of the oral health of their inpatient infants in maternity or infirmary units of a public hospital. Methods: Questionnaire applications were scheduled and educational lectures were carried out on how to sanitize the infant's mouth after breastfeeding, even in the absence of primary teeth, emphasizing the importance of breastfeeding. Results: A significant number of mothers reported that they received no guidance regarding the oral health care of their infants. They had never attended lectures by dental practitioners, as well as they did not know that the use of pacifier, baby bottle and digital sucking habit could interfere with their infant’s oral heath over time. Conclusions: The majority declared that they had no care with the oral health of their infants. Only five mothers of newborns reported that they performed the oral hygiene of them once a day after the first breastfeeding. The mothers showed lack of knowledge on the diseases which can affect their children during early infancy as they had no information on how to prevent them. They did not know that early caries lesions could affect the infant and that harmful oral habits can predispose to the development of malocclusions.

scholarly journals How combining different caries lesions characteristics may be helpful in short-term caries progression prediction: model development on occlusal surfaces of primary teeth

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Isabela Floriano ◽  
Elizabeth Souza Rocha ◽  
Ronilza Matos ◽  
Juliana Mattos-Silveira ◽  
Kim Rud Ekstrand ◽  
...  
Keyword(s):  
Goodness Of Fit ◽  
Primary Teeth ◽  
Clinical Parameters ◽  
Short Term ◽  
Caries Lesion ◽  
Occlusal Surfaces ◽  
Caries Progression ◽  
One Year ◽  
Caries Lesions ◽  
Cavitated Lesions

Abstract Background Few studies have addressed the clinical parameters' predictive power related to caries lesion associated with their progression. This study assessed the predictive validity and proposed simplified models to predict short-term caries progression using clinical parameters related to caries lesion activity status. Methods The occlusal surfaces of primary molars, presenting no frank cavitation, were examined according to the following clinical predictors: colour, luster, cavitation, texture, and clinical depth. After one year, children were re-evaluated using the International Caries Detection and Assessment System to assess caries lesion progression. Progression was set as the outcome to be predicted. Univariate multilevel Poisson models were fitted to test each of the independent variables (clinical features) as predictors of short-term caries progression. The multimodel inference was made based on the Akaike Information Criteria and C statistic. Afterwards, plausible interactions among some of the variables were tested in the models to evaluate the benefit of combining these variables when assessing caries lesions. Results 205 children (750 surfaces) presented no frank cavitations at the baseline. After one year, 147 children were reassessed (70%). Finally, 128 children (733 surfaces) presented complete baseline data and had included primary teeth to be reassessed. Approximately 9% of the reassessed surfaces showed caries progression. Among the univariate models created with each one of these variables, the model containing the surface integrity as a predictor had the lowest AIC (364.5). Univariate predictive models tended to present better goodness-of-fit (AICs < 388) and discrimination (C:0.959–0.966) than those combining parameters (AIC:365–393, C:0.958–0.961). When only non-cavitated surfaces were considered, roughness compounded the model that better predicted the lesions' progression (AIC = 217.7, C:0.91). Conclusions Univariate model fitted considering the presence of cavitation show the best predictive goodness-of-fit and discrimination. For non-cavitated lesions, the simplest way to predict those lesions that tend to progress is by assessing enamel roughness. In general, the evaluation of other conjoint parameters seems unnecessary for all non-frankly cavitated lesions.

scholarly journals Remineralization of natural early caries lesions in vitro by P11-4 monitored with photothermal radiometry and luminescence

2017 ◽  
Vol 8 (4) ◽  
pp. e12257 ◽  
Author(s):  
Joshua D. Silvertown ◽  
Bonny P. Y. Wong ◽  
Koneswaran S. Sivagurunathan ◽  
Stephen H. Abrams ◽  
Jennifer Kirkham ◽  
...  
Keyword(s):  
Photothermal Radiometry ◽  
Early Caries ◽  
Caries Lesions

Optical Methods for the Detection and Quantification of Caries

1987 ◽  
Vol 1 (1) ◽  
pp. 14-20 ◽  
Author(s):  
B. Angmar-Månsson ◽  
J.J. Ten Bosch
Keyword(s):  
Light Source ◽  
Bright Light ◽  
Optical Signal ◽  
Diagnostic Methods ◽  
Optical Methods ◽  
Prophylactic Measures ◽  
Reliable Diagnosis ◽  
Early Caries ◽  
Caries Lesions ◽  
Detection And Quantification

The commonly used clinical methods are inadequate for reliable diagnosis of caries lesions until demineralization is established. By the time a reliable diagnosis can be made, the damage is often irreversible, and restorative methods may be necessary to prevent further progress of the lesions. Early detection of the caries lesion would enable the dentist, by using effective prophylactic measures, to provide remineralization and conservation of the tooth substance rather than restoration of the dentition. Attempts to improve traditional methods or to develop new methods of detecting caries lesions have been numerous. Most of the presently used diagnostic methods require visual observation of an optical signal. Reflected light is used tc detect changes in color, texture, and translucency of the tooth substance. The tools required are a bright light source and a mouth mirror. With special methods utilizing drying, magnification, and photography, the sensitivity of the method can be increased. Various optical methods for the detection and quantification of caries will be discussed - for example, fiber optic transillumination, ultraviolet illumination, the use of various dyes, and fluorescent or non-fluorescent substances to enhance the contrast between the carious and the sound enamel. This presentation will focus on the following two methods: (1) a method that uses visible laser light within the blue-green region as the light source to improve signal-to-noise ratio and increase sensitivity for detection of early caries lesions, and (2) a recently developed quantitative method based on the scattering of light by enamel crystals in relation to their surrounding environment. The possibilities and limitations of the different methods will be critically evaluated. In the near future, optical methods for the detection and quantification of early caries lesions will provide efficient tools for reliable evaluation of caries-preventive measures.

scholarly journals Dye-enhanced laser fluorescence detection on natural caries lesions in primary teeth

2015 ◽  
Vol 21 (3) ◽  
pp. 145
Author(s):  
Fausto Medeiros Mendes ◽  
Victor Moreira Leamari ◽  
Márcia Turolla Wanderley ◽  
Mariana Minatel Braga ◽  
Juliana Mattos-Silveira ◽  
...  
Keyword(s):  
Primary Teeth ◽  
Fluorescent Dyes ◽  
Protoporphyrin Ix ◽  
Polarized Light ◽  
Laser Fluorescence ◽  
Primary Molars ◽  
Smooth Surfaces ◽  
Occlusal Caries ◽  
Occlusal Surfaces ◽  
Caries Lesions

Objective: This study aimed to investigate the association of two fluorescent dyes and Laser Fluorescence (LF) device in detecting smooth and occlusal natural caries in primary teeth in vitro.Methods: Measurements were performed with the LF and with LF associated with tetrakis (N-methylpyridyl)porphyrin (LF TMPyP) and protoporphyrin IX (LF PPIX) in 72 smooth (63 primary molars) and 134 occlusal sites (81 primary molars). For validation, surfaces were sectioned and sections obtained were evaluated under stereomicroscope. Smooth surfaces were also evaluated using polarized light microscopy and Knoop microhardness. For both smooth and occlusal surfaces, ROC analyses were performed, and sensitivities, specificities and accuracies were assessed. In smooth surfaces, Pearson’s correlation coefficients between LF values and lesions hardness or lesions depth were calculated.Results: LF TMPyP presented higher correlation with hardness and lesion depth than other methods in smooth surfaces. No differences were observed in other parameters among the methods, in both smooth and occlusal surfaces.Relevance: The LF TMPyP might improve performance in quantifying smooth-surface caries lesions in primary teeth. However, the sensitivity is improved at D2 (caries extending into inner half of the enamel but not to amelodentinal junction) threshold when using PPIX in smooth caries lesions. The association of LF with fluorescent dyes does not improve the performance on occlusal caries.

Sign in / Sign up

Export Citation Format

Share Document