Inappropriate prescribing of proton pump inhibitors in hospitalized patients

2011 ◽  
Vol 7 (5) ◽  
pp. 421-425 ◽  
Author(s):  
Mark Reid ◽  
Angela Keniston ◽  
J. Christie Heller ◽  
Marshall Miller ◽  
Sofia Medvedev ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Inappropriate Prescribing ◽  
Hospitalized Patients

scholarly journals Inappropriate Prescription of Proton Pump Inhibitors in a Community Setting

2018 ◽  
Vol 71 (4) ◽  
Author(s):  
Patrick Viet-Quoc Nguyen ◽  
Raja Tamaz
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Inappropriate Prescribing ◽  
Hospital Setting ◽  
Community Setting ◽  
Platelet Aggregation Inhibitors ◽  
Ambulatory Setting ◽  
Inappropriate Prescription ◽  
Patients Âgés ◽  
Service Des Urgences

<p>ABSTRACT</p><p><strong>Background</strong>: Proton pump inhibitors (PPIs) are widely prescribed for gastrointestinal conditions, such as gastroesophageal reflux disease and dyspepsia, and for prevention of gastric ulcer. Although previous reports<br />have described inappropriate prescription of PPIs in the hospital setting, data from the community are lacking.</p><p><strong>Objective</strong>: To assess PPI prescriptions in the ambulatory setting.</p><p><strong>Methods</strong>: Patients presenting to the emergency department of a teaching hospital between June 2016 and March 2017 were prospectively assessed for use of a PPI at home. The appropriateness of PPI prescription was<br />evaluated on the basis of an interview with the patient and review of the medical record. The indication for PPI therapy was verified against current guidelines for the province of Quebec.</p><p><strong>Results</strong>: Over the 9-month study period, 2417 patients were screened, of whom 871 were included in the study. In relation to the Quebec guidelines, PPI prescription was inappropriate for 267 (30.7%) of the patients. When prescription of PPI for ulcer prevention in certain groups of patients (age ≥ 65 years and using acetylsalicylic acid or platelet aggregation inhibitors; age ≥ 75 years and using celecoxib) was re-classified as appropriate, the proportion of inappropriate PPI prescriptions declined to 20.3% (177/871).</p><p><strong>Conclusions</strong>: These findings suggest that inappropriate prescribing of PPIs remains problematic in the community setting in the province of Quebec.</p><p>RÉSUMÉ</p><p><strong>Contexte</strong> : Les inhibiteurs de la pompe à protons (IPP) sont largement prescrits pour traiter les troubles gastro-intestinaux, comme le reflux gastro-oesophagien et la dyspepsie, et pour prévenir l’ulcère gastrique. Bien<br />que des rapports antérieurs aient parlé de la prescription inadéquate des IPP dans les établissements de santé, il n’y a pas de données provenant de la communauté.</p><p><strong>Objectif</strong> : Évaluer la pertinence des prescriptions d’IPP dans un milieu ambulatoire.</p><p><strong>Méthodes</strong> : Les patients se présentant au service des urgences d’un hôpital universitaire entre juin 2016 et mars 2017 ont été évalués de façon prospective relativement à l’utilisation d’un IPP à la maison. La pertinence de la prescription d’un IPP a été jugée d’après une entrevue avec le patient et l’analyse du dossier médical. On a vérifié si l’indication pour un traitement par IPP respectait les lignes directrices actuelles du Québec.</p><p><strong>Résultats</strong> : Sur une période de neuf mois, 2 417 patients ont été évalués et 871 d’entre eux ont été admis à l’étude. Par rapport aux lignes directrices du Québec, la prescription d’IPP était inadéquate pour 267 (30,7 %) des patients. Or, si la prescription d’IPP pour prévenir l’ ulcère gastrique chez certains groupes de patients (âgés de 65 ans ou plus et prenant de l’acide acétylsalicylique ou un antiagrégant plaquettaire; âgés de 75 ans ou plus et prenant du célécoxib) était reclassée comme adéquate, la proportion de prescriptions d’IPP inadéquates reculait à 20,3 % (177/871).</p><p><strong>Conclusions</strong> : Ces résultats laissent croire que les prescriptions inadéquates d’IPP demeurent un problème dans le contexte communautaire au Québec.<br /><br /></p>

Inappropriate Prescribing of Proton Pump Inhibitors in Older Patients

Drugs & Aging ◽  
2012 ◽  
Vol 29 (8) ◽  
pp. 681-690 ◽  
Author(s):  
Hanifat Hamzat ◽  
Hao Sun ◽  
Joanna C. Ford ◽  
Joan MacLeod ◽  
Roy L. Soiza ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Older Patients ◽  
Inappropriate Prescribing

scholarly journals Investigation on Intervention Effects of Applying Proton Pump Inhibitors in Inpatients

2019 ◽  
Author(s):  
Guotong Qing ◽  
Jian Wu ◽  
Runfong Wei ◽  
Di Wu ◽  
Yipping Gou ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Age Distribution ◽  
Information Management System ◽  
Hospitalized Patients ◽  
Utilization Rate ◽  
Coincidence Rate ◽  
Cross Sectional ◽  
Clinical Pharmacists ◽  
Before And After

Abstract Background. To investigate the intervention effect of clinical pharmacists on irrational use of proton pump inhibitors (PPIs) in clinicians. Methods. A cross-sectional study was used to through the hospital information management system survey, before intervention (July 15th, 2016, Aug 15th, 2016 and Sep 15th 2016) and dry prognosis (July 15th, 2017, Aug 15th, 2017 and Sep 15th, 2017) all the use of PPIs inpatients related information. According to the guidelines of "drug instructions" and "experts on stress ulcer prevention and treatment experts", the standard of drug use was formulated, and the use of PPIs before and after intervention was evaluated and analyzed in accordance with the standard, and the results of intervention were evaluated. Results. The total number of hospitalized patients surveyed before the intervention was 1,693, the average utilization rate of proton pump inhibitors was 27.05% and the coincidence rate was 52.40%. The total number of hospitalized patients investigated after the intervention was 2,095, the average utilization rate of proton pump inhibitors was 8.54%, and the coincidence rate was 68.16%. Before and after the intervention, there was no difference in gender ratio and age distribution, the decrease of the utilization rate and the improvements of the qualified rate after intervention were statistically significant.Conclusion. According to the standards of PPIs, clinical pharmacists strictly implement the special prescription review system and other intervention measures, which can significantly improve the level of PPIs rational clinical medication.

scholarly journals PTU-001 Overuse Of Proton Pump Inhibitors And Strategies To Reduce Inappropriate Prescribing

Gut ◽  
2014 ◽  
Vol 63 (Suppl 1) ◽  
pp. A37.2-A37 ◽  
Author(s):  
C Owen ◽  
DJB Marks ◽  
P Panesar
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Inappropriate Prescribing
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