Three‐dimensional turbo‐spin‐echo amide proton transfer‐weighted mri for cervical cancer: A preliminary study

2019 ◽  
Vol 50 (4) ◽  
pp. 1318-1325 ◽  
Author(s):  
Yong‐Lan He ◽  
Yuan Li ◽  
Cheng‐Yu Lin ◽  
Ya‐Fei Qi ◽  
Xiaoqi Wang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Proton Transfer ◽  
Spin Echo ◽  
Three Dimensional ◽  
Amide Proton ◽  
Turbo Spin Echo ◽  
Turbo Spin ◽  
Amide Proton Transfer ◽  
Preliminary Study

Amide proton transfer imaging for differentiation of tuberculomas from high-grade gliomas: Preliminary experience

2021 ◽  
pp. 197140092110027
Author(s):  
Karthik Kulanthaivelu ◽  
Shumyla Jabeen ◽  
Jitender Saini ◽  
Sanita Raju ◽  
Atchayaram Nalini ◽  
...  
Keyword(s):  
Proton Transfer ◽  
Chemical Exchange ◽  
Spin Echo ◽  
Chemical Exchange Saturation Transfer ◽  
Amide Proton ◽  
High Grade ◽  
Saturation Pulse ◽  
Amide Proton Transfer ◽  
High Grade Gliomas ◽  
Amide Protons

Purpose Tuberculomas can occasionally masquerade as high-grade gliomas (HGG). Evidence from magnetisation transfer (MT) imaging suggests that there is lower protein content in the tuberculoma microenvironment. Building on the principles of chemical exchange saturation transfer and MT, amide proton transfer (APT) imaging generates tissue contrast as a function of the mobile amide protons in tissue’s native peptides and intracellular proteins. This study aimed to further the understanding of tuberculomas using APT and to compare it with HGG. Method Twenty-two patients ( n = 8 tuberculoma; n = 14 HGG) were included in the study. APT was a 3D turbo spin-echo Dixon sequence with inbuilt B0 correction. A two-second, 2 μT saturation pulse alternating over transmit channels was applied at ±3.5 ppm around water resonance. The APT-weighted image (APTw) was computed as the MT ratio asymmetry (MTRasym) at 3.5 ppm. Mean MTRasym values in regions of interest (areas = 9 mm2; positioned in component with homogeneous enhancement/least apparent diffusion coefficient) were used for the analysis. Results MTRasym values of tuberculomas ( n = 14; 8 cases) ranged from 1.34% to 3.11% ( M = 2.32 ± 0.50). HGG ( n = 17;14 cases) showed MTRasym ranging from 2.40% to 5.70% ( M = 4.32 ± 0.84). The inter-group difference in MTRasym was statistically significant ( p < 0.001). APTw images in tuberculomas were notable for high MTRasym values in the perilesional oedematous-appearing parenchyma (compared to contralateral white matter; p < 0.001). Conclusion Tuberculomas demonstrate lower MTRasym ratios compared to HGG, reflective of a relative paucity of mobile amide protons in the ambient microenvironment. Elevated MTRasym values in perilesional parenchyma in tuberculomas are a unique observation that may be a clue to the inflammatory milieu.

scholarly journals Diagnostic performance of 3D TSE MRI versus 2D TSE MRI of the knee at 1.5 T, with prompt arthroscopic correlation, in the detection of meniscal and cruciate ligament tears

2016 ◽  
Vol 49 (2) ◽  
pp. 69-74 ◽  
Author(s):  
Francisco Abaeté Chagas-Neto ◽  
Marcello Henrique Nogueira-Barbosa ◽  
Mário Müller Lorenzato ◽  
Rodrigo Salim ◽  
Maurício Kfuri-Junior ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Diagnostic Performance ◽  
Spin Echo ◽  
Cruciate Ligament ◽  
Three Dimensional ◽  
Meniscal Tears ◽  
Turbo Spin Echo ◽  
Turbo Spin ◽  
Anterior Cruciate ◽  
Cruciate Ligament Tears

Abstract Objective: To compare the diagnostic performance of the three-dimensional turbo spin-echo (3D TSE) magnetic resonance imaging (MRI) technique with the performance of the standard two-dimensional turbo spin-echo (2D TSE) protocol at 1.5 T, in the detection of meniscal and ligament tears. Materials and Methods: Thirty-eight patients were imaged twice, first with a standard multiplanar 2D TSE MR technique, and then with a 3D TSE technique, both in the same 1.5 T MRI scanner. The patients underwent knee arthroscopy within the first three days after the MRI. Using arthroscopy as the reference standard, we determined the diagnostic performance and agreement. Results: For detecting anterior cruciate ligament tears, the 3D TSE and routine 2D TSE techniques showed similar values for sensitivity (93% and 93%, respectively) and specificity (80% and 85%, respectively). For detecting medial meniscal tears, the two techniques also had similar sensitivity (85% and 83%, respectively) and specificity (68% and 71%, respectively). In addition, for detecting lateral meniscal tears, the two techniques had similar sensitivity (58% and 54%, respectively) and specificity (82% and 92%, respectively). There was a substantial to almost perfect intraobserver and interobserver agreement when comparing the readings for both techniques. Conclusion: The 3D TSE technique has a diagnostic performance similar to that of the routine 2D TSE protocol for detecting meniscal and anterior cruciate ligament tears at 1.5 T, with the advantage of faster acquisition.

Preliminary Study of 1.5-T MR Arthrography of the Shoulder With 3D Isotropic Intermediate-Weighted Turbo Spin Echo

2012 ◽  
Vol 199 (1) ◽  
pp. W107-W113 ◽  
Author(s):  
Leon D. Rybak ◽  
Renata La Rocca Vieira ◽  
Michael Recht ◽  
Timothy Shepard ◽  
Graham Wiggins ◽  
...  
Keyword(s):  
Spin Echo ◽  
Mr Arthrography ◽  
Turbo Spin Echo ◽  
Turbo Spin ◽  
Preliminary Study
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