Editorial for “Quality Control of MR Elastography Using Percent Measurable Liver Volume Estimation”

Author(s):  
Andrew T. Trout ◽  
Jean A. Tkach
Author(s):  
David H. Ballard ◽  
Daniel R. Ludwig ◽  
Tyler J. Fraum ◽  
Amber Salter ◽  
Vamsi R. Narra ◽  
...  

2021 ◽  
Vol 15 (11) ◽  
pp. 3030-3033
Author(s):  
Amer Latif ◽  
M Akif Dilshad ◽  
Sumbul Naz ◽  
Sadia Jabbar ◽  
Faisal Naseer ◽  
...  

Aims & Objectives: Corner stone in performing living donor liver transplant is to assess and predict the adequacy of the donated liver for recipient and remaining liver. Previously the conversion of liver volume to estimated weight is done by using unit to unit conversion with a factor of 1. We analyzed data of our institute to research the methodology and local applicability of the same. Place and duration of study: Shaikh Zayed Hospital, Lahore. January 2011 to June 2017 Material & Methods: Retrospective data was collected for the first 115 recipients and donors. Their preoperative liver volumes calculated by C.T scan and post-operative graft harvested with weights were compared. Results: The parameter of actual volume of right lobe averaged to 769.77 ± 12.73 gm varying with a quantum of 17.73% (426 – 1123 gm). Estimated volume of right lobe of liver varied 358 to 1218 ml (CV = 17.84%) with an average value of 798.96 ± 13.29 ml. Results of linear regression between estimated volume of right lobe and actual weight of the right lobe in gm was significantly linear (r = 0.830, r2 = 0.690, adj. r2 = 0.689 and F = 250.98, p < 0.0001), showing that volumetric assessment overestimated graft weight/volume. Following is equation generated from our data for graft weight estimation. Actual right lobe (g) = 134.004 + 0.796 (estimated right lobe volume (ml) ± 76.42. Conclusion: Using one to one principle for volume estimation of healthy liver can be misleading and therefore we propose an equation to reach more accurate estimation of graft weight. Keywords: living donor liver transplant, CT volumetry, graft to body weight ratio


2016 ◽  
Vol 51 (4) ◽  
pp. 422-426 ◽  
Author(s):  
Olga M Will ◽  
Timo Damm ◽  
Graeme M Campbell ◽  
Witigo von Schönfells ◽  
Yahya Açil ◽  
...  

The partial hepatectomy (PH) model is widely used to study liver regeneration. Currently, the extent of regeneration is analyzed by measuring the weight of the liver post-mortem or by magnetic resonance imaging. In this study we aimed to determine whether liver volume gain can be accurately measured using micro-computed tomography (microCT). Approximately 42% of the liver was removed by ligation in C57BL/6 N mice. Mice were divided into two study groups. In group 1 conventional characterization of liver hyperplasia was performed by weighing the liver post-mortem. In group 2, liver volume gain was determined by microCT volume estimation. MicroCT results showed equivalent regeneration rates compared with the conventional method without the need to mathematically determine initial liver weights before PH. This parameter is strongly influenced by the age, strain and sex of the mice. In addition non-invasive microCT determination of volume gain over multiple time-points using the same animal reduces the number of animals needing to be used (in line with the 3R principle of replacement, reduction and refinement).


2012 ◽  
Vol 6 (1) ◽  
pp. 180-186 ◽  
Author(s):  
Masahito Aoyama ◽  
Yoshiharu Nakayama ◽  
Kazuo Awai ◽  
Yukihiro Inomata ◽  
Yasuyuki Yamashita

Author(s):  
Partha Sarathi Ain ◽  
Uttam Kumar Roy ◽  
Krishna Sen ◽  
Debes Ray ◽  
Jayanta Pal

Introduction: Liver volume estimation is an essential component prior to major hepatic surgery and liver transplantation. Liver volume is evaluated with different formulae, gold standard Computed Tomography (CT) volumetry and Magnetic Resonance Imaging (MRI). As per literature review, studies comparing ultrasonography with formula based liver volume estimation are very few. Ultrasonography is non-invasive in nature and inexpensive. It is gaining popularity among clinicians as it helps in rapid evaluation of liver volumes. Aim: To compare variability of liver volume using 2D ultrasound with a standard well-established method based on formula derived by Johnson et al. Materials and Methods: This was a cross-sectional study done between August-October 2020 and patients were selected by the physician from general Outpatient Department (OPD) pool and clinically screened for further biochemical studies. Participants aged 20-60 years with normal liver function test were recruited in the study. Images were taken on a Siemens Ultrasound System. Study variables included were liver volumes estimated by two methods, age, weight, height and Body Surface Area (BSA). F test was used to compare variability between liver volumes estimated by two different methods. Bivariate correlation between ultrasonography-based liver volume and different body indices was also tested. Results: Variability comparison using F test shows no significant difference (F=1.095, df1=149, df2=149, p=0.29). Liver volumes estimated by two methods showed good correlation with each other and is significant at the 0.01 level, r=0.574. The mean difference (125 cc) in volumes between two methods were statistically significant (t=10.92, degree of freedom=149, p<0.001) and were not in agreement with each other. Body parameters were correlated with liver volume estimated by 2D ultrasound. Conclusion: Ultrasonography is a useful tool in estimating liver volume prior to major hepatic resection. Formula based calculation of Standard Liver Volume (SLV) does not agree with USG based volume and underestimates the mean liver volume obtained by USG method.


Radiology ◽  
2021 ◽  
Author(s):  
Alberto A. Perez ◽  
Victoria Noe-Kim ◽  
Meghan G. Lubner ◽  
Peter M. Graffy ◽  
John W. Garrett ◽  
...  

Author(s):  
Shimaa Farghaly ◽  
Marwa Makboul ◽  
Mahmoud Refaat Shehata

Abstract Background Liver volume estimation is considered as an integral part in preoperative evaluation in patients undergoing liver transplantation; computed tomography and magnetic resonance imaging are considered the gold standard methods for liver volume estimation, and both are reliable and valid in determination of liver volume via manual and semi-automated methods. Reliable and accurate set of three simple measurement planes using two-dimensional ultrasound for volumetric assessment of liver was determined, and predictive equation using these three simple measurements was performed, which is simple to perform and easy to calculate, in order to evaluate liver volume and validate these measurements against CT images. Our aim in this study was to evaluate the efficacy and validity of two-dimensional ultrasound in liver volume estimation compared to CT volumetry as a gold standard. Results A strong linear positive correlation with no statistical significant difference was found between 2D US and semi-automated CT volumetric, and result was r = 0.7402 and p > 0.05, with an average liver volume of 1572.10 (± 326.43) cm3 and 1559.30 (± 381.02) cm3 respectively. No statistically significant difference was found also between the two modalities in different age groups and different sexes. Conclusion Simple linear two-dimensional ultrasound could be considered an efficient, accurate, and trustable tool for liver volume measurement in clinical practice.


1982 ◽  
Vol 57 (4) ◽  
pp. 283-286 ◽  
Author(s):  
G. W Rylance ◽  
T. A Moreland ◽  
M. D Cowan ◽  
D. C Clark

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