Micro‐CT analysis of the Lisfranc complex reveals higher bone mineral density in dorsal compared to plantar regions

2021 ◽  
Author(s):  
Melissa R. Requist ◽  
Yantarat Sripanich ◽  
Tim Rolvien ◽  
Amy L. Lenz ◽  
Alexej Barg
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Ct ◽  
Mineral Density ◽  
Ct Analysis

Newly Formed Bone around Implanted New Titanium Alloy: Ti-15%Zr-4%Nb-4%Ta

2007 ◽  
Vol 361-363 ◽  
pp. 661-664
Author(s):  
Hiroshi Nakada ◽  
Yasuko Numata ◽  
Taketoshi Suwa ◽  
Y. Okazaki ◽  
Racquel Z. LeGeros ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Titanium Alloy ◽  
Surface Treatment ◽  
Bone Mineral ◽  
Ti Alloy ◽  
Micro Ct ◽  
Mineral Density ◽  
Biological Safety ◽  
Biological Performance

We have developed a new Ti alloy, Ti-15%Zr-4%Nb-4%Ta alloy (Ti-15-4-4) that showed higher biological safety and mechanical properties than the currently used Ti-6%Al-4%V alloy. The purpose of this study is to determine the biological performance of the new alloy. Ti-15-4-4 implants (machined or blasted) were placed in surgically created defects in rabbit femurs. The rabbits were sacrificed after 4, 8, 16, 24 and 48 weeks. Bone mineral density (BMD) and area of newly formed bone around the implants were measured using micro-CT. Results showed that the Ti-15-4-4 alloy is biocompatible and forms new bone around the Ti-15-4-4 implant, regardless of the surface treatment. The BMD and area of newly formed bone around the blasted implant surfaces were significantly greater than those around the machined surfaces. These results indicate that the new Ti-15-4-4 alloy has a potential for use as implants and has the advantage of improved mechanical properties described in earlier studies.

scholarly journals Analysis of Bone Mineral Density and Area of Newly Formed Bone Around Implants Using Micro-CT After Pull-Out Tests

2007 ◽  
Vol 5 (2) ◽  
pp. 97-106 ◽  
Author(s):  
Hiroshi Nakada ◽  
Taketoshi Suwa ◽  
Yasuko Numata ◽  
Yoshimitsu Okazaki ◽  
Toshiro Sakae ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Ct ◽  
Mineral Density ◽  
Pull Out

A New Osteoporosis Prevention Supplements-diet Improve Bone Mineral Density in Ovariectomized Rats on Micro-CT

2014 ◽  
Vol 23 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Hiroshi Nakada ◽  
Toshiro Sakae ◽  
Takehiro Watanabe ◽  
Takahiro Takahashi ◽  
Kanami Fujita ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Ovariectomized Rats ◽  
Micro Ct ◽  
Osteoporosis Prevention ◽  
Mineral Density

Bone mineral density measurements on cortical and trabecular specimens: Validation of a densitometric calibration protocol for in-vitro micro-CT

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S179
Author(s):  
L. Mecozzi ◽  
R. Stoico ◽  
S. Tassani ◽  
F. Particelli ◽  
F. Baruffaldi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Ct ◽  
Mineral Density ◽  
Density Measurements ◽  
Calibration Protocol

scholarly journals Failure strength of human vertebrae: Prediction using bone mineral density measured by DXA and bone volume by micro-CT

Bone ◽  
2012 ◽  
Vol 50 (6) ◽  
pp. 1416-1425 ◽  
Author(s):  
Egon Perilli ◽  
Andrew M. Briggs ◽  
Susan Kantor ◽  
John Codrington ◽  
John D. Wark ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Bone Volume ◽  
Failure Strength ◽  
Micro Ct ◽  
Mineral Density

scholarly journals Micro-CT and histological analysis of Ti6Al7Nb custom made implants with hydroxyapatite and SiO2-TiO2 coatings in a rabbit model

2015 ◽  
Vol 88 (3) ◽  
pp. 408-414 ◽  
Author(s):  
Gabriel Armencea ◽  
Cristian Berce ◽  
Horatiu Rotaru ◽  
Simion Bran ◽  
Dan Leordean ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Selective Laser Melting ◽  
Histological Examination ◽  
Bone Mineral ◽  
Rabbit Model ◽  
Micro Ct ◽  
Mineral Density ◽  
Laser Melting ◽  
Implant Surface ◽  
Custom Made

Background and aim. Bone defect reconstruction in the maxillofacial area comes as a necessity after traumatic, oncological or congenital pathology. Custom made implant manufacturing, such as selective laser melting (SLM), is very helpful when bone reconstruction is needed. In the present study we assessed the osseointegration of custom made implants made of Ti6Al7Nb with two different coatings: SiO2-TiO2 and hydroxyapatite, by comparing the bone mineral density (BMD) measured on micro-CT and the histological mineralized bone surrounding the implants.Methods. Custom made – cylindrical type – implants were produced by selective laser melting, coated with SiO2-TiO2 and hydroxyapatite and implanted in the rabbit femur. The animals (divided into 3 groups) were sacrificed at 1, 3 and 6 months and the implants were removed together with the surrounding bone. Bone mineral density and histological examination of the bone-implant surface was performed for each group. Results. BMD and histological examination of the samples determined the quantity of mineralized bone at the implant site, showing a good percentage of mineralized bone for the coated implants at 1, 3 and 6 months,  The measurements for the implants without coating showed a significant lower quantity of mineralized bone at 3 months compared with the implants with coating, and a good quantity of mineralized bone at 6 months, showing a process of demineralization followed by remineralization in the last month. The measurements of BMD showed similar results with the histological examination.Conclusions. The use of micro-CT and the measurement of BMD are a reliable, minimally invasive and a quick method of osseointegration assessment.

scholarly journals Bone microarchitectural parameters can detect oxytocin induced changes prior to bone density on mitigating bone deterioration in rabbit osteoporosis model using micro-CT

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Yuyou Qiu ◽  
Cuisong Tang ◽  
Mario Serrano-Sosa ◽  
Jian Hu ◽  
Jingqi Zhu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Volume Fraction ◽  
Rabbit Model ◽  
Vehicle Group ◽  
Control Group ◽  
Micro Ct ◽  
Mineral Density ◽  
Bone Volume Fraction ◽  
Trabecular Thickness

Abstract Background This study is aimed to determine the efficacy of X-Ray Microtomography (micro-CT) in predicting oxytocin (OT) treatment response in rabbit osteoporosis(OP) model. Methods Sixty-five rabbits were randomly divided into three groups: control group, ovariectomy (OVX) -vehicle and OVX-oxytocin group. The controls underwent sham surgery. OVX-vehicle and OVX-oxytocin groups were subjected to bilateral OVX. The rabbits in OVX-oxytocin group were injected with oxytocin. In the 0th, 4th, 8th, 10th and 12th weeks post OVX operation, bone mineral density (BMD) and bone micro-architectural parameters were measured in three groups. Results Bone mineral density (BMD), bone volume fraction (BV/TV), Trabecular Number (Tb.N), and Trabecular Thickness (Tb.Th) decreased, while Trabecular Spacing (Tb.Sp) and Structure Model Index (SMI) increased overtime in all the three groups. In OVX-oxytocin group, the bone deterioration tendency is slowing down compared with that of the OVX-vehicle group. The BMD of the OVX-oxytocin group was significantly lower than those in the OVX-vehicle group at 12th week (P = 0.017). BV/TV and Tb.Sp in OVX-oxytocin group changed significantly from 8th week (P = 0.043) and 12th week (P = 0.014), which is earlier than that of BMD and other bone micro-architectural parameters. Conclusion BV/TV and Tb.Sp changed prior to BMD and other bone micro-architectural parameters with oxytocin intervention, which indicate that they are more sensitive markers for predicting early osteoporosis and treatment monitoring when using micro-CT to evaluate osteoporosis rabbit model.

Sign in / Sign up

Export Citation Format

Share Document