Preparative High-Performance Liquid Chromatography and Preparative Thin-Layer Chromatography Isolation of Tocainide Carbamoyl-Glucuronide: Structural Characterization by Gas Chromatography-Mass Spectrometry and Fast Atom Bombardment-Mass Spectrometry

1990 ◽  
Vol 79 (10) ◽  
pp. 857-861 ◽  
Author(s):  
David W.K. Kwok ◽  
Gopalakrishna Pillai ◽  
Radana Vaughan ◽  
James E. Axelson ◽  
Keith M. McErlane
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Thin Layer ◽  
High Performance ◽  
Fast Atom Bombardment ◽  
Preparative Thin Layer Chromatography ◽  
Gas Chromatography Mass Spectrometry ◽  
Layer Chromatography

scholarly journals A Tetrodotoxin-Producing Vibrio Strain, LM-1, from the Puffer Fish Fugu vermicularis radiatus

2000 ◽  
Vol 66 (4) ◽  
pp. 1698-1701 ◽  
Author(s):  
Myoung-Ja Lee ◽  
Dong-Youn Jeong ◽  
Woo-Seong Kim ◽  
Hyun-Dae Kim ◽  
Cheorl-Ho Kim ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Thin Layer ◽  
High Performance ◽  
Gas Chromatography Mass Spectrometry ◽  
Mouse Bioassay ◽  
Puffer Fish ◽  
Layer Chromatography

ABSTRACT Identification of tetrodotoxin (TTX) and its derivatives produced from a Vibrio strain in the intestine of the puffer fishFugu vermicularis radiatus was performed by thin-layer chromatography, electrophoresis, high-performance liquid chromatography, and gas chromatography-mass spectrometry, together with a mouse bioassay for toxicity. It was demonstrated that the isolated bacterium produced TTX, 4-epi-TTX, and anhTTX during cultivation, suggesting that Vibrio strains are responsible for the toxification of the puffer fish.

Separation and Identification of Phencyclidine and Some of Its Analogs

1983 ◽  
Vol 66 (5) ◽  
pp. 1186-1195
Author(s):  
K Gurudath Rao ◽  
Shiv K Soni
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Mass Spectra ◽  
Major Ions ◽  
Gas Chromatography Mass Spectrometry ◽  
Structural Variations ◽  
Layer Chromatography

Abstract l-(l-Phenylcyclohexyl)piperidine (PCP) and 9 of its analogs have been separated and identified by using thin layer chromatography, high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS), and infrared spectroscopy (IR). Spectral and chromatographic characteristics are discussed in terms of the structural variations observed in these compounds. Some compounds decomposed on the GC column; the HPLC procedure is a helpful substitute. A tentative scheme is proposed for the fragmentation of the major ions observed in the mass spectra. The effect of substitution on the IR spectra of the analogs was investigated.

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