scholarly journals Adaptive silver films for surface-enhanced Raman spectroscopy of biomolecules

2005 ◽  
Vol 36 (6-7) ◽  
pp. 648-656 ◽  
Author(s):  
Vladimir P. Drachev ◽  
Mark D. Thoreson ◽  
Vishal Nashine ◽  
Eldar N. Khaliullin ◽  
Dor Ben-Amotz ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Silver Films ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Revisiting semicontinuous silver films as surface-enhanced Raman spectroscopy substrates

2019 ◽  
Vol 10 ◽  
pp. 1048-1055 ◽  
Author(s):  
Malwina Liszewska ◽  
Bogusław Budner ◽  
Małgorzata Norek ◽  
Bartłomiej J Jankiewicz ◽  
Piotr Nyga
Keyword(s):  
Raman Spectroscopy ◽  
Percolation Threshold ◽  
Physical Vapor Deposition ◽  
Surface Enhanced Raman Spectroscopy ◽  
Silver Films ◽  
Analytical Technique ◽  
Detection And Identification ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
The Many

Surface-enhanced Raman spectroscopy (SERS) is a very promising analytical technique for the detection and identification of trace amounts of analytes. Among the many substrates used in SERS of great interest are nanostructures fabricated using physical methods, such as semicontinuous metal films obtained via electron beam physical vapor deposition. In these studies, we investigate the influence of morphology of semicontinuous silver films on their SERS properties. The morphologies studied ranged from isolated particles through percolated films to almost continuous films. We found that films below the percolation threshold (transition from dielectric-like to metal-like) made of isolated silver structures provided the largest SERS enhancement of 4-aminothiophenol (4-ATP) analyte signals. The substrate closest to the percolation threshold has the SERS signal about four times lower than the highest signal sample.

Uniform Near-Spherical Nanoscale Silver Films for Surface-Enhanced Raman Spectroscopy Sensing

2020 ◽  
Vol 3 (2) ◽  
pp. 2008-2015
Author(s):  
Zhifeng Dou ◽  
Zhendong Zhao ◽  
Mingnan Zhang ◽  
Yanli Xie ◽  
Wenhui Yu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Silver Films ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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