Human laryngeal sensory receptor mapping illuminates the mechanisms of laryngeal adductor reflex control

99mTc-HMPAO-SPECT and SPECT with the 123I-labelled benzodiazepine (Bz) receptor ligand Ro 16-0154 were performed in 10 patients suffering from partial epilepsy, without cerebral lesion in MRT or CT. 2 h p.i. of Ro 16-0154 the distribution of activity correlated with the known distribution of Bz- receptors in the human brain. Perfusion and receptor-binding were found decreased in 7 patients of each study in the suspicious brain-area. 123l-labelled Ro 16-0154 is suitable for Bz-receptor mapping by SPECT. The decrease of Bz-receptor binding in epileptic foci, as described in PET-studies, was also detected by SPECT in 7 of 10 patients.

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Faculty Opinions recommendation of Broca's region: novel organizational principles and multiple receptor mapping.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5793962.5776063 ◽

2010 ◽

Author(s):

Lutz Jäncke ◽

Martin Meyer

Keyword(s):

Receptor Mapping ◽

Broca’S Region ◽

Organizational Principles ◽

Multiple Receptor

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Nano-Mechanics and Membrane Receptor Mapping of CD8 + T Cells (Supplementry Material)

Current Nanoscience ◽

10.2174/157341309789378096 ◽

2009 ◽

Vol 5 (4) ◽

pp. 465-469

Author(s):

Yangzhe Wu ◽

Yi Hu ◽

Hongsong Lu ◽

Jiye Cai ◽

Xianhui He ◽

...

Keyword(s):

T Cells ◽

Cd8 T Cells ◽

Membrane Receptor ◽

Receptor Mapping

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Sensory Transduction

10.1093/oso/9780198835028.001.0001 ◽

2019 ◽

Cited By ~ 2

Author(s):

Gordon L. Fain

Keyword(s):

Ion Channels ◽

Receptor Cell ◽

Electrical Response ◽

Second Messengers ◽

Sensory Transduction ◽

Sensory Receptor ◽

Signal Pathways ◽

Sense Organs ◽

Sensory Physiology ◽

Effector Molecules

Sensory Transduction provides a thorough and easily accessible introduction to the mechanisms that each of the different kinds of sensory receptor cell uses to convert a sensory stimulus into an electrical response. Beginning with an introduction to methods of experimentation, sensory specializations, ion channels, and G-protein cascades, it provides up-to-date reviews of all of the major senses, including touch, hearing, olfaction, taste, photoreception, and the “extra” senses of thermoreception, electroreception, and magnetoreception. By bringing mechanisms of all of the senses together into a coherent treatment, it facilitates comparison of ion channels, metabotropic effector molecules, second messengers, and other components of signal pathways that are common themes in the physiology of the different sense organs. With its many clear illustrations and easily assimilated exposition, it provides an ideal introduction to current research for the professional in neuroscience, as well as a text for an advanced undergraduate or graduate-level course on sensory physiology.

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Evidence Against the Central Nervous System Involved in Altered Reflex Control of Sympathetic Nerve Activity by Atrial Natriuretic Peptide

Clinical and Experimental Hypertension Part A Theory and Practice ◽

10.3109/10641968809075978 ◽

1988 ◽

Vol 10 (sup1) ◽

pp. 263-268 ◽

Cited By ~ 1

Author(s):

S. Suzuki ◽

A. Takeshita ◽

T. Imaizumi ◽

Y. Hirooka ◽

M. Yoshida ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Atrial Natriuretic Peptide ◽

Natriuretic Peptide ◽

Sympathetic Nerve ◽

Sympathetic Nerve Activity ◽

Nerve Activity ◽

The Central Nervous System ◽

Reflex Control ◽

Atrial Natriuretic

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The reciprocal jaw-muscle reflexes elicited by anterior- and back-tooth-contacts—a perspective to explain the control of the masticatory muscles

BDJ Open ◽

10.1038/s41405-020-00056-z ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Lauri Vaahtoniemi

Keyword(s):

Masticatory Muscles ◽

Food Bolus ◽

Dental Patients ◽

Adductor Muscles ◽

Jaw Muscle ◽

Class 1 ◽

Reflex Control ◽

Control Hypothesis ◽

Muscle Reflexes ◽

Inhibitory Reflex

Abstract Aims Tooth-contact sensations are considered essential to boost jaw adductor muscles during mastication. However, no previous studies have explained the importance of the inhibitory reflex of human anterior-tooth (ANT)-contacts in mastication. Here I present the “reciprocal reflex-control-hypothesis” of mammalian mastication. Subjects and setting of the study I demonstrate the hypothesis with the live kinematics of free jaw-closures as inferred from T-Scan recordings of dental patients. Results The jaw-closures started with negligible force, predominantly with ANT-contacts (the AF-bites). The first ANT-contact inhibited the first kinematic tilt of the mandible, whereas the bites starting from a back-tooth (BAT)-contact (the BF-bites) accelerated the first tilt. The second tilt established a low-force static tripod of the ANT- and bilateral BAT-contacts for a fixed mandible-maxilla relation. Thereafter, semi-static bite force increased rapidly, relatively more in the BAT-area. Discussion and Conclusions In the vertical-closure phase of chewing, the primate joint-fulcrum (class 3 lever) conflicts with the food-bolus-fulcrum in the BAT-area (class 1 lever). The resilient class 3 and 1 lever systems are superseded by an almost static mechanically more advantageous class 2 lever with a more rigid fulcrum at the most anterior ANT-contact. For humans, the class 2 levered delivery of force also enables forceful horizontal food grinding to be extended widely to the BAT-area.

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