Novel Anti-Microbial Host-Guest Complexes Based on Cationic β-Cyclodextrin Polymers and Triclosan/Butylparaben

2007 ◽  
Vol 28 (23) ◽  
pp. 2244-2248 ◽  
Author(s):  
Yong Guan ◽  
Liying Qian ◽  
Huining Xiao
Keyword(s):  
Cyclodextrin Polymers ◽  
Microbial Host

β-Cyclodextrin Polymers on Microcrystalline Cellulose as a Granular Media for Organic Micropollutant Removal from Water

2018 ◽  
Author(s):  
Diego Alzate-Sanchez ◽  
Yuhan Ling ◽  
Chenjun Li ◽  
Benjamin Frank ◽  
Reiner Bleher ◽  
...  
Keyword(s):  
Microcrystalline Cellulose ◽  
Continuous Flow ◽  
Granular Media ◽  
Anaerobic Biodegradation ◽  
Thin Coating ◽  
Micropollutant Removal ◽  
Cyclodextrin Polymers ◽  
Flow Experiments ◽  
Aerobic And Anaerobic ◽  
Cellulose Composite

This manuscript describes cyclodextrin polymers formed as a thin coating on microcrystalline cellulose. The resulting polymer/cellulose composite shows promising performance for removing organic pollutants from water and can be packed into columns for continuous-flow experiments. The polymer/cellulose composite also shows excellent resistance to aerobic and anaerobic biodegradation.

Crosslinker Chemistry Determines the Uptake Potential of Perfluorinated Alkyl Substances by β-Cyclodextrin Polymers

2018 ◽  
Author(s):  
Leilei Xiao ◽  
Casey Ching ◽  
Yuhan Ling ◽  
Mohammadreza Nasiri ◽  
Max Justin Klemes ◽  
...  
Keyword(s):  
Binding Affinity ◽  
Polymer Networks ◽  
Cyclodextrin Polymer ◽  
Perfluorinated Alkyl Substances ◽  
Cyclodextrin Polymers

This work describes several crosslinked β-cyclodextrin polymer networks and correlates the crosslinker chemistry with binding affinity for per- and polyfluorinated alkyl substances (PFASs), including PFOA and PFOS.

Preparation, Characterization, Toxicity and Pharmacodynamics of the Inclusion Complex of Brucea javanica Oil with β-cyclodextrin Polymers

2018 ◽  
Vol 18 (10) ◽  
pp. 855-861
Author(s):  
Rong-Rong Xu ◽  
Rong Hu ◽  
Lin Chen ◽  
Bo Pan ◽  
Xing-Chen Wang ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Brucea Javanica ◽  
Cyclodextrin Polymers ◽  
Brucea Javanica Oil

Phosphorus-containing cyclodextrin polymers: metal cations and hydroxyapatite affinities

2014 ◽  
Vol 80 (1-2) ◽  
pp. 101-106 ◽  
Author(s):  
Véronique Wintgens ◽  
Pierre Dubot ◽  
Gisèle Volet ◽  
Bernard Sébille ◽  
Catherine Amiel
Keyword(s):  
Metal Cations ◽  
Phosphorus Containing ◽  
Cyclodextrin Polymers

Extraction of phenols from aqueous solutions by β-cyclodextrin polymers. Comparison of sorptive capacities with other sorbents

2008 ◽  
Vol 68 (1) ◽  
pp. 406-413 ◽  
Author(s):  
Ana Romo ◽  
Francisco Javier Peñas ◽  
José Ramón Isasi ◽  
Iñigo X. García-Zubiri ◽  
Gustavo González-Gaitano
Keyword(s):  
Aqueous Solutions ◽  
Cyclodextrin Polymers

Cyclodextrin polymers decorated with RGD peptide as delivery systems for targeted anti-cancer chemotherapy

2018 ◽  
Vol 37 (4) ◽  
pp. 771-778 ◽  
Author(s):  
Maurizio Viale ◽  
Rita Tosto ◽  
Valentina Giglio ◽  
Giuseppe Pappalardo ◽  
Valentina Oliveri ◽  
...  
Keyword(s):  
Cancer Chemotherapy ◽  
Delivery Systems ◽  
Rgd Peptide ◽  
Anti Cancer ◽  
Cyclodextrin Polymers

scholarly journals Microbially guided discovery and biosynthesis of biologically active natural products

2021 ◽  
Author(s):  
Ankur Sarkar ◽  
Edward Kim ◽  
Taehwan Jang ◽  
Akarawin Hongdusit ◽  
Hyungjun Kim ◽  
...  
Keyword(s):  
Natural Products ◽  
Tyrosine Phosphatase ◽  
Biologically Active ◽  
Allosteric Site ◽  
Terpene Synthases ◽  
Guided Discovery ◽  
Detection Systems ◽  
Treatment Of Diabetes ◽  
Active Natural ◽  
Microbial Host

Abstract The design of small molecules that inhibit disease-relevant proteins represents a longstanding challenge of medicinal chemistry. Here, we describe an approach for encoding this challenge—the inhibition of a human drug target—into a microbial host and using it to guide the discovery and biosynthesis of targeted, biologically active natural products. This approach identified two previously unknown terpenoid inhibitors of protein tyrosine phosphatase 1B (PTP1B), an elusive therapeutic target for the treatment of diabetes and cancer. Both inhibitors appear to target an allosteric site, which confers selectivity, and can inhibit PTP1B in living cells. A screen of 24 uncharacterized terpene synthases from a pool of 4,464 genes uncovered additional hits, demonstrating a scalable discovery approach, and the incorporation of different PTPs into the microbial host yielded alternative PTP-specific detection systems. Findings illustrate the potential for using microbes to discover and build natural products that exhibit precisely defined biochemical activities yet possess unanticipated structures and/or binding sites.

scholarly journals Geosmin Sorption on Cyclodextrin Polymers

2013 ◽  
Vol 04 (05) ◽  
pp. 24-29
Author(s):  
Redel Gutierrez ◽  
Niwooti Whangchai ◽  
Nakao Nomura
Keyword(s):  
Cyclodextrin Polymers
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