Daily energy expenditure, physical activity, and weight loss in Parkinson's disease patients

We examined the hypothesis that weight loss in heart failure patients is associated with elevated daily energy expenditure. Twelve cachectic patients [age = 73 +/- 6 yr; weight loss = 15 +/- 6 kg; body mass index (BMI) = 21 +/- 5 kg/m2], 13 noncachectic patients (age = 67 +/- 5 yr; BMI = 27 +/- 5 kg/m2), and 50 healthy elderly controls (age = 69 +/- 6 yr; BMI = 26 +/- 4 kg/m2) were studied. Daily energy expenditure and it components were measured using doubly labeled water and indirect calorimetry and body composition by dual-energy X-ray absorptiometry. Fat mass and fat-free mass were lower (P < 0.05) in cachectic patients compared with noncachectic patients and healthy controls. Daily energy expenditure was lower (P < 0.05) in cachectic patients (1,870 +/- 347 kcal/day) compared with noncachectic patients (2,349 +/- 545 kcal/day) and healthy controls (2,543 +/- 449 kcal/day). Differences in daily energy expenditure were primarily due to lower (P < 0.05) physical activity energy expenditure in cachectic (269 +/- 307 kcal/day) and noncachectic patients (416 +/- 361 kcal/day) compared with healthy controls (728 +/- 374 kcal/day). A lower (P < 0.05) resting energy expenditure was also noted in cachectic patients (1,414 +/- 210 kcal/day) compared with noncachectic patients (1,698 +/- 252 kcal/day) and healthy controls (1,561 +/- 223 kcal/day). These findings show that daily energy expenditure is not higher, but significantly lower, in cachectic heart failure patients due to lower physical activity and resting energy expenditure. These results argue against the hypothesis that an abnormally elevated daily energy expenditure is associated with weight loss in heart failure.

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Impacts of vigorous and non-vigorous activity on daily energy expenditure

Proceedings of The Nutrition Society ◽

10.1079/pns2003279 ◽

2003 ◽

Vol 62 (3) ◽

pp. 645-650 ◽

Cited By ~ 44

Author(s):

Klaas R. Westerterp

Keyword(s):

Physical Activity ◽

Body Size ◽

Energy Expenditure ◽

Exercise Training ◽

Physical Activity Level ◽

High Intensity ◽

Activity Level ◽

Daily Energy Expenditure ◽

Activity Intensity ◽

Daily Energy

Activity intensity is a potential determinant of activity-induced energy expenditure. Tri-axial accelerometery is the most objective measurement technique for the assessment of activity intensity, in combination with doubly-labelled water for the measurement of energy expenditure under free-living conditions. Data on the effects of subject characteristics, including body size and age, and exercise training on the relationship between activity intensity and daily energy expenditure are reviewed. Average daily metabolic rate and non-basal energy expenditure are positively related to body size. The duration and intensity of physical activities do not need to be equivalent to the energy spent on activity. Obese subjects spend more energy on physical activity but can perform fewer activities, especially high-intensity (weight-bearing) activities, because of their higher body weight. Physical activity generally declines gradually from about 60 years of age onwards. Most subjects >80 years have an activity level well below the level defined for sedentary middle-aged adults. Spending relatively more time on low-intensity activities has a negative effect on the mean physical activity level. To obtain a higher physical activity level does not necessarily imply high-intensity activities. In an average subject 25% of the activity-induced energy expenditure may be attributed to high-intensity activities. Exercise training, as a form of high-intensity activity, affects the physical activity level more in younger subjects than in elderly subjects.

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